Antibiotic Stewardship

Penicillin Allergy Linked to MRSA, <i>C. Difficile</i> Risk

Penicillin Allergy Linked to MRSA, C. Difficile Risk

There is a correlation for documented penicillin allergy with increased risk of MRSA and C diff, which is mediated by increased use of β-lactam alternative antibiotics.

48-Hour Automatic Stop Order Effectively Decreased NICU Antibiotic Doses

48-Hour Automatic Stop Order Effectively Decreased NICU Antibiotic Doses

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A 48-hour automatic stop order for antibiotics embedded within a NICU admission order set effectively reduced antibiotic use.

Resistant <i>A Baumannii</i> Rose in Children From 1999 to 2012

Resistant A Baumannii Rose in Children From 1999 to 2012

Between 1999 and 2012, Acinetobacter baumannii antibiotic resistance increased in children.

Increased Need for Antibiotic Stewardship in Outpatient Settings

Increased Need for Antibiotic Stewardship in Outpatient Settings

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A review summarizes outpatient prescription practices and identifies factors that may influence physician prescribing behaviors.

Improvements Needed in Antibiotic Stewardship in the Neonatal Setting

Improvements Needed in Antibiotic Stewardship in the Neonatal Setting

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Early antibiotic use was examined among very low birth weight infants across hospitals in the United States.

Rapid Diagnostics Reduce Time to Optimal Antimicrobial Therapy in Children

Rapid Diagnostics Reduce Time to Optimal Antimicrobial Therapy in Children

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Time to optimal antimicrobial therapy for positive blood cultures was assessed in a pediatric population.

Empirical Use of Antibiotics for Resistant Infections Not Associated With Survival

Empirical Use of Antibiotics for Resistant Infections Not Associated With Survival

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Researchers found no association between starting colistin before final culture results and survival at 14 and 28 days.

Macrolides for Asthma Management: An Updated Review

Macrolides for Asthma Management: An Updated Review

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While macrolides had no direct effect on lung function, their use significantly improved asthma control and quality of life in patients with asthma.

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

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Researchers examined the association of timing, frequency, and class of antibiotic use during pregnancy on the development of childhood asthma.

Pharmacists Play Role in Cutting Hospital-Acquired Infections

Pharmacists Play Role in Cutting Hospital-Acquired Infections

Pharmacists are increasingly becoming involved in antibiotic surveillance, including e-surveillance methods; formulation of antibiotic-use policies; and day-to-day control of problematic antibiotic use.

Combating Medically Important Antibiotic Use in Food-Producing Animals

Combating Medically Important Antibiotic Use in Food-Producing Animals

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The new WHO guidelines restricts antibiotic use in animals for purposes of growth promotion as well as avoidance of use for disease prevention.

No Benefit From Prophylactic Antimicrobials in Aspiration Pneumonitis

No Benefit From Prophylactic Antimicrobials in Aspiration Pneumonitis

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Use of prophylactic antimicrobial therapy was not associated with a reduction in mortality or transfer to critical care compared with patients managed with supportive care only.

Antibiotic Rotation in ICU Does Not Reduce Prevalence of Antibiotic-Resistant Bacteria

Antibiotic Rotation in ICU Does Not Reduce Prevalence of Antibiotic-Resistant Bacteria

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Findings from the study did not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods reduced the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.

Antibiotic Stewardship: Role of MRSA Nasal Screening

Antibiotic Stewardship: Role of MRSA Nasal Screening

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MRSA nares screening can be a stewardship tool to streamline empiric antibiotic therapy among those not nares colonized with MRSA.

Characteristics Associated With Inappropriate Antibiotic Prescribing

Characteristics Associated With Inappropriate Antibiotic Prescribing

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Investigators identified patient, provider, and practice characteristics associated with antibiotic prescribing in an attempt to determine factors contributing to inappropriate antimicrobial use.

How Often Do Patients Select Antibiotics Over Surgery for Acute Appendicitis?

How Often Do Patients Select Antibiotics Over Surgery for Acute Appendicitis?

Although most patients would choose surgical intervention for treatment of acute uncomplicated appendicitis, some would opt for antibiotics alone.

Prolonged Antibiotic Prophylaxis May Increase CDI Risk After Cardiac Surgery

Prolonged Antibiotic Prophylaxis May Increase CDI Risk After Cardiac Surgery

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Readmissions for CDI occurred close to hospital discharge, consistent with the CDC's surveillance study findings.

Antibiotics, Mechanical Bowel Preparation Associated With Reduced SSIs

Antibiotics, Mechanical Bowel Preparation Associated With Reduced SSIs

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Oral antibiotics combined with mechanical bowel preparation should be considered for all patients undergoing left-sided colorectal cancer resections.

Inappropriate Antibiotic Use for Acute Bronchitis Highest in Younger Adults

Inappropriate Antibiotic Use for Acute Bronchitis Highest in Younger Adults

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The adult population is a key target of antibiotic stewardship efforts for acute bronchitis, since over half of unnecessary prescribing for bronchitis occurs in adult patients.

Factors Associated With Lower Risk for Early-Onset Sepsis in Premature Infants

Factors Associated With Lower Risk for Early-Onset Sepsis in Premature Infants

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Identification of premature infants at low risk of early onset sepsis may help guide decisions for initiating and/or discontinuing empirical antibiotic treatments in the first days of life.

Are Antibiotic Stewardship Programs the Antidote to Antibiotic Overuse?

Are Antibiotic Stewardship Programs the Antidote to Antibiotic Overuse?

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Optimizing outcomes with an antibiotic stewardship programs requires a team approach that involves point-of-care providers.

Long-Term Behavioral Interventions on Inappropriate Antibiotic Prescribing

Long-Term Behavioral Interventions on Inappropriate Antibiotic Prescribing

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Inappropriate prescribing of antibiotics is a contributing factor in antibiotic resistance.

Pediatric Outpatient Antimicrobial Stewardship: Minimizing Antibiotic Duration

Pediatric Outpatient Antimicrobial Stewardship: Minimizing Antibiotic Duration

Hear from experts on when to prescribe short course antibiotic therapy in pediatric populations for a variety of common infections.

Efficacy of Procalcitonin-Guided Antimicrobial Stewardship Initiative for Diagnosing Pneumonia

Efficacy of Procalcitonin-Guided Antimicrobial Stewardship Initiative for Diagnosing Pneumonia

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Implementation of a procalcitonin diagnostic algorithm improves diagnostic yield and reduces hospital length of stay in bacterial pneumonia.

Combating Irrational and Inappropriate Antibiotic Prescribing Practices

Combating Irrational and Inappropriate Antibiotic Prescribing Practices

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A substantial portion of cases of antibiotic overprescription are linked to overdiagnosis of conditions such as sinusitis and otitis media without meeting diagnostic criteria and with high variability in diagnosis by race and by clinician.

"Hard Stop" Alert May Reduce <i>C difficile</i> Orders for Laxative-Taking Patients

"Hard Stop" Alert May Reduce C difficile Orders for Laxative-Taking Patients

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A "hard stop" requiring providers to think critically about C difficile testing in the presence of laxative use or absence of documented diarrhea strengthened CDI testing stewardship.

Dexamethasone Reduces Need for Antibiotics in Adults With Sore Throat

Dexamethasone Reduces Need for Antibiotics in Adults With Sore Throat

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Looking for a way to reduce inappropriate antibiotic use for adults with acute sore throats, researchers evaluated whether as single dose of oral corticosteriod can effectively reduce likelihood of symptom resolution.

Advances in Point-of-Care Testing and Tips for Clinicians

Advances in Point-of-Care Testing and Tips for Clinicians

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An expert interview on recent developments in molecular point-of-care and near-patient testing for infectious diseases.

Antibiotic Prescribing Habits Vary Widely Across Practices in Children With CAP

Antibiotic Prescribing Habits Vary Widely Across Practices in Children With CAP

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Although published guidelines recommend amoxicillin in most children with community-acquired pneumonia, due to nonclinical factors, macrolides and broad-spectrum antibiotics continue to be prescribed.

Reducing Antibiotic Use in Infants With Use of Sepsis Risk Calculator

Reducing Antibiotic Use in Infants With Use of Sepsis Risk Calculator

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A study finds the use of early-onset sepsis calculator can decrease the number of infants receiving a sepsis work-up and prophylactic antibiotics.

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