Antibiotics, Antimicrobial Resistance

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Role of Vaccines in the Fight Against Antimicrobial Resistance

Role of Vaccines in the Fight Against Antimicrobial Resistance

The potential role of vaccinations in combatting antimicrobial resistance (AMR) is currently undervalued. The distribution and development of new vaccines should be priorities in efforts to address the AMR crisis.

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FDA Warns Against Long-Term Azithromycin Use for Some

FDA Warns Against Long-Term Azithromycin Use for Some

The FDA is warning patients with cancers of the blood or lymph nodes who undergo a donor stem cell transplant not to take azithromycin,

High Dose Pivmecillinam Effective for UTIs Caused by Resistant Escherichia coli

High Dose Pivmecillinam Effective for UTIs Caused by Resistant Escherichia coli

Pivmecillinam treatment for community-acquired urinary tract infections (UTIs) caused by ESBL-producing Escherichia coli is a reasonable option.

Antibiotics Often Unnecessary for Sacral Pressure Ulcers Complicated by Osteomyelitis

Antibiotics Often Unnecessary for Sacral Pressure Ulcers Complicated by Osteomyelitis

A systematic literature review, published in Clinical Infectious Diseases, found no evidence supporting a benefit to antibacterial therapy for osteomyelitis in patients with stage IV sacral pressure ulcers.

FDA Approves Omadacycline for Skin Infections, Pneumonia

FDA Approves Omadacycline for Skin Infections, Pneumonia

The Committee's recommendation was based on data from the omadacycline global development program that included nearly 2000 adults in three Phase 3 studies.

Resistance to Antibiotic Treatments for H pylori Infection

Resistance to Antibiotic Treatments for H pylori Infection

The resistance of Helicobacter pylori to antibiotics is increasing worldwide, with primary and secondary resistance to clarithromycin, metronidazole, and levofloxacin reaching levels higher than 15%.

Some Bacteria Now More Tolerant of Alcohol-Based Sanitizers

Some Bacteria Now More Tolerant of Alcohol-Based Sanitizers

Some types of bacteria are developing tolerance of alcohol-based hand sanitizers used in hospitals.

Ciprofloxacin May Increase Likelihood of Aortic Dissection, Rupture

Ciprofloxacin May Increase Likelihood of Aortic Dissection, Rupture

In a mouse model of moderate, sporadic aortic aneurysm and dissection (AAD), ciprofloxacin increases susceptibility to aortic dissection and rupture.

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

Inappropriate antibiotic prescriptions were highest among urgent care facilities (45.7%), with emergency departments (24.6%), medical offices (17.0%), and retail clinics (14.4%) following.

Ampicillin Plus Ceftriaxone: An Effective Alternative for E faecalis Infective Endocarditis

Ampicillin Plus Ceftriaxone: An Effective Alternative for E faecalis Infective Endocarditis

Ampicillin plus ceftriaxone was an effective treatment for penicillin-susceptible Enterococcus faecalis infective endocarditis compared with ampicillin plus gentamicin.

Prevalence of Resistant Urinary Tract Infections Outpacing Antimicrobial Treatment

Prevalence of Resistant Urinary Tract Infections Outpacing Antimicrobial Treatment

Approximately 6% of all patients presenting at an emergency department during a one year period with a UTI were diagnosed with an ESBL-producing Enterobacteriaceae infection.

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