antibiotics

Daptomycin Effective in Treating Serious Skin Infections in Children

Daptomycin Effective in Treating Serious Skin Infections in Children

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Intravenous daptomycin may be effective and well-tolerated in children, possibly providing an alternative treatment against methicillin-resistant Staphylococcus aureus (MRSA) skin infections in this patient population.

Treatment of Appendicitis With Antibiotics Alone a Viable Option

Treatment of Appendicitis With Antibiotics Alone a Viable Option

Avoiding surgery and treating appendicitis with antibiotics alone may be a safe approach for many children.

High Rate of Metronidazole Resistance Seen in <i>C difficile</i> Infection

High Rate of Metronidazole Resistance Seen in C difficile Infection

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Antibiotic resistance to therapies for Clostridium difficile infection are common, and their patterns should be considered in algorithms designed to select therapies.

Restricting Fluoroquinolone Use Helped With CDI Decline in England

Restricting Fluoroquinolone Use Helped With CDI Decline in England

The outbreak of Clostridium difficile in England that began in 2006 was curbed by reducing the use of fluoroquinolones, according to a study.

Efficacy of Antibiotic Prescribing Interventions in Hospitals Assessed

Efficacy of Antibiotic Prescribing Interventions in Hospitals Assessed

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Interventions used to help physicians prescribe antibiotics properly were effective at raising compliance with antibiotic policy and decreasing the duration of treatment, according to a Cochrane review.

Increase Otitis Media Risk in Children With Antibiotic Use During Pregnancy

Increase Otitis Media Risk in Children With Antibiotic Use During Pregnancy

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Maternal antibiotic use during pregnancy increases the risk of otitis media and treatment with ventilation tubes in offspring.

Intrapartum Azithromycin Decreases Maternal, Neonatal Infections

Intrapartum Azithromycin Decreases Maternal, Neonatal Infections

Azithromycin given to women in labor decreases infections in both women and newborns during the puerperal period.

Avycaz Update: New Data on Difficult to Treat Pathogens

Avycaz Update: New Data on Difficult to Treat Pathogens

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FDA has approved an update to the Avycaz (ceftazidime and avibactam) label to include Phase 3 clinical data supporting the treatment of patients with complicated urinary tract infections (cUTI).

Optimizing Treatments in Obese Patients With SSTIs

Optimizing Treatments in Obese Patients With SSTIs

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When treating skin and soft tissue infections (SSTIs) in obese patients, the pharmacokinetic/pharmacodynamic approach offers important data and decision-making tools for optimizing regimens.

Injectable Antibiotic Drug Recalled

Injectable Antibiotic Drug Recalled

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Hospira announced a voluntary recall of one lot of Vancomycin HCl for Injection, USP, after a confirmed report of particulate matter discovered in a single vial.

Novel Antibiotic Shows Promise in Treating Complicated UTI

Novel Antibiotic Shows Promise in Treating Complicated UTI

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Novel antibiotic, cefiderocol (S-649266) shows promise for the treatment of patients with complicated UTI by Gram-negative bacteria.

Superbug Resistant to All Available Antimicrobials

Superbug Resistant to All Available Antimicrobials

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A Nevada woman was found to be infected with a pan-resistant superbug.

Oral Antibiotics as Effective as Fecal Transplant for <i>C difficile</i>

Oral Antibiotics as Effective as Fecal Transplant for C difficile

Results showed no real difference in outcomes when comparing fecal transplant and antibiotic treatment.

Antimicrobial Options Assessed for Community-Acquired Pneumonia

Antimicrobial Options Assessed for Community-Acquired Pneumonia

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More effective antimicrobial treatments are needed to reduce adverse events burden for patients with community-acquired pneumonia (CAP).

Infection in Infancy Not Antibiotic Use Linked to Childhood Obesity

Infection in Infancy Not Antibiotic Use Linked to Childhood Obesity

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Infection, rather than antibiotic use, is associated with increased risk of childhood obesity.

Duration of Antibiotic Use in Acute Otitis Media

Duration of Antibiotic Use in Acute Otitis Media

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Children on 5-day regimen had more treatment failures, less reduction in symptoms.

Microbiology Labs Play an Important Role in Antimicrobial Stewardship

Microbiology Labs Play an Important Role in Antimicrobial Stewardship

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Microbiology labs play an important role in antimicrobial stewardship and resistance monitoring, but are underused.

Systemwide Hospital Stewardship Reduces Misuse, Cost of Antibiotics

Systemwide Hospital Stewardship Reduces Misuse, Cost of Antibiotics

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Systemwide implementation of hospital stewardship programs reduced inappropriate use and cost of antibiotics.

Bacteria Linked to Periodontal Disease May Trigger RA

Bacteria Linked to Periodontal Disease May Trigger RA

Aggregatibacter actinomycetemcomitans may be trigger of autoimmunity in rheumatoid arthritis.

Frequency of Nontyphoidal <i>Salmonella</i> Infections Estimated

Frequency of Nontyphoidal Salmonella Infections Estimated

There are about 6,200 resistant culture-confirmed nontyphoidal Salmonella infections annually.

Interventions to Reduce Antibiotic Overuse in NICUs

Interventions to Reduce Antibiotic Overuse in NICUs

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Appropriate interventions to reduce automatic overuse of antibiotics in one level 3 NICU successfully identified areas of stewardship without reducing safety.

Generic Tygacil Antibacterial Injection Available

Generic Tygacil Antibacterial Injection Available

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Fresenius Kabi's genetic tigecycline injections will be available beginning in 2017.

Promising Results for Pulmaquin in Treating Lung Infections in Non-CF Bronchiectasis

Promising Results for Pulmaquin in Treating Lung Infections in Non-CF Bronchiectasis

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Two phase 3 trials (ORBIT-3 and ORBIT-4) yielded promising results for Pulmaquin (inhaled ciprofloxacin) in treating patients with non-CF bronchiectasis who have chronic lung infections with P aeruginosa.

Clinical Practice Guideline on UTI in Young Children Reaffirmed

Clinical Practice Guideline on UTI in Young Children Reaffirmed

After review of literature, the 2011 clinical practice guideline on urinary tract infection in infants and young children reaffirmed.

Does International Travel Spread Antimicrobial-Resistant Bacteria?

Does International Travel Spread Antimicrobial-Resistant Bacteria?

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Researchers swabbed over 400 airport door handles in 59 countries, then conducted cultures to determine the most commonly found bacterial species.

Study to Evaluate Shorter Course Antibiotics Use in Children

Study to Evaluate Shorter Course Antibiotics Use in Children

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An NIAID sponsored clinical trial will assess effectiveness of a 5-day course of antibiotics in treating community-acquired pneumonia in children.

Skin Infections From Drug Resistant <i>S aureus</i> Tied to Livestock

Skin Infections From Drug Resistant S aureus Tied to Livestock

A recent study found that hog workers in the North Carolina are developing skin infections from multidrug-resistant Staphylococcus aureus.

Guideline for Surgical Antimicrobial Prophylaxis Developed

Guideline for Surgical Antimicrobial Prophylaxis Developed

Clinical practice guideline developed for surgical antimicrobial prophylaxis using ADAPTE and the Guideline Implementability Appraisal (GLIA).

Meropenem-Vaborbactam Promising for Complicated UTI Treatment

Meropenem-Vaborbactam Promising for Complicated UTI Treatment

Researchers saw success in 98.4% of patients being treated with meropenem-vaborbactam.

Antibiotic Use Limits Death in Cirrhosis, Upper GI Bleeding

Antibiotic Use Limits Death in Cirrhosis, Upper GI Bleeding

Timely antibiotic administration reduces 30-day mortality among patients with cirrhosis and upper gastrointestinal bleeding.

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