antimicrobial resistance

FDA Approves New Intravenous, Oral Antibiotic for Skin Infections

FDA Approves New Intravenous, Oral Antibiotic for Skin Infections

By

The FDA has approved delafloxacin (Baxdela™, Melinta Therapeutics), a new antibacterial drug to treat acute bacterial skin and skin structure infections.

Case of <i>Vibrio vulnificus</i> Septic Shock Leading to Death After New Tattoo

Case of Vibrio vulnificus Septic Shock Leading to Death After New Tattoo

By

A patient who recently acquired a new tattoo developed Vibrio vulnificus septic shock after swimming in seawater, leading to death.

High Prevalence of MDR Bacteria in Residents Living in Nursing Homes

High Prevalence of MDR Bacteria in Residents Living in Nursing Homes

Multidrug-resistant gram-negative bacteria can be found in more than 1-quarter of nursing-home residents.

Congressional Acts Pose Threat to National ID Health Initiatives

Congressional Acts Pose Threat to National ID Health Initiatives

By

Passage of the 2017 budget, along with congressional approval of the AHCA, leaves large holes in the funding of the proposed national approach to infectious disease control.

Efficacy of Antibiotic Regimens Compared for Treating PID

Efficacy of Antibiotic Regimens Compared for Treating PID

By

A Cochrane review of antibiotic treatments for pelvic inflammatory disease found no definitive evidence that one treatment was more effective or safer than the other.

Increase Risk of Spontaneous Abortion With Antibiotic Use

Increase Risk of Spontaneous Abortion With Antibiotic Use

By

Using certain antibiotics during early pregnancy increases the risk of spontaneous abortion.

Telavancin Efficacy Against Difficult-to-Treat Pathogens

Telavancin Efficacy Against Difficult-to-Treat Pathogens

By

Theravance Biopharma announced positive results from 3 studies on Vibativ (telavancin), a lipoglycopeptide antibiotic.

Novel Bacteriophage Treatment Successfully Treats Drug-Resistant Infection

Novel Bacteriophage Treatment Successfully Treats Drug-Resistant Infection

Scientists at the University of California San Diego School of Medicine successfully used experimental therapy involving bacteriophages to treat a patient with a multi-drug resistant bacterial infection.

Does Use of Azithromycin Increase Risk of Ventricular Arrhythmia?

Does Use of Azithromycin Increase Risk of Ventricular Arrhythmia?

Patients who took azithromycin weren't any more likely to develop ventricular arrhythmia than those taking amoxicillin.

Long-term Antibiotic Use in Adulthood May Increase Colorectal Adenoma Risk

Long-term Antibiotic Use in Adulthood May Increase Colorectal Adenoma Risk

Long-term use of antibiotics in early to middle adulthood may increases risk of colorectal adenomas in women.

Can a Maple Syrup Extract Enhance Antibiotic Potency?

Can a Maple Syrup Extract Enhance Antibiotic Potency?

Nathalie Tufenkji, PhD, and colleagues at McGill University in Québec found that a phenolic rich extract from maple syrup (PRMSE) can increase the potency of commonly used antibiotics, ciprofloxacin and carbencillin, against Escherichia coli, Proteus mirabilis, and Pseudomonas aeruginosa.

New Antibiotic Therapy Improves Acute Lung Function in Children With CF

New Antibiotic Therapy Improves Acute Lung Function in Children With CF

New antibiotic therapy is associated with greater likelihood of recovery after acute lung function decline in children with cystic fibrosis.

New Bill Before Congress Aims at Addressing Antibiotic Resistance Problem

New Bill Before Congress Aims at Addressing Antibiotic Resistance Problem

By

Antibiotic resistance has a high mortality rate, and the problem is growing as manufacturers retreat from investing in new drugs and diagnostic tests.

Antiprotozoal Renders Gram-Negative Bacteria Susceptible to Antibiotics

Antiprotozoal Renders Gram-Negative Bacteria Susceptible to Antibiotics

By

Investigations in vitro and in mouse models showed that pentamidine, an antifungal and antiprotozoal agent, rendered Gram-negative pathogens susceptible to conventional antibiotics, even in the setting of colistin resistance.

High Rates of Antibiotic Resistance in Infected Diabetic Foot Ulcers

High Rates of Antibiotic Resistance in Infected Diabetic Foot Ulcers

By

A carbapenem with vancomycin is the least resistant initial antibiotic combination to use in patients with an infected diabetic foot ulcer.

Comparative Efficacy of Topical Mupirocin, Gentamicin in Preventing PD-related Infections

Comparative Efficacy of Topical Mupirocin, Gentamicin in Preventing PD-related Infections

By

Researchers found topical gentamicin is a better treatment compared to mupirocin for prophylaxis against bacterial infections in patients on peritoneal dialysis.

 Lower Odds of Post-Cesarean Maternal Infection With Azithromycin

Lower Odds of Post-Cesarean Maternal Infection With Azithromycin

Only 8.8% of women undergoing cesarean section had post-cesarean infection when treated with pre-incision azithromycin prophylaxis.

Can Patient, Physician Co-Washing Increase Hand Washing Practice?

Can Patient, Physician Co-Washing Increase Hand Washing Practice?

Offering hand sanitizer to the patient and clinician at the same time, deemed "co-washing," is a simple intervention that can be implemented in almost any practice and possibly reduce infection rates.

Is Antibiotic Treatment Effective in Children With Mild Eczema?

Is Antibiotic Treatment Effective in Children With Mild Eczema?

Researchers find use of antibiotics ineffective for mild clinically infected eczema in children.

Hospital Room Floors May be Unrecognized Pathogen Dissemination Source

Hospital Room Floors May be Unrecognized Pathogen Dissemination Source

Disinfecting surfaces is key to preventing nosocomial transmission of pathogens such as C difficile, MRSA, and vancomycin-resistant enterococci.

WHO Prioritizes Antibiotic-Resistant Bacteria on Pathogens List

WHO Prioritizes Antibiotic-Resistant Bacteria on Pathogens List

By

The World Health Organization has developed a global priority list of pathogens for the research and development of new antibiotics.

Hospital Sinks May Spread Multidrug-Resistant Bacteria

Hospital Sinks May Spread Multidrug-Resistant Bacteria

After colonizing in drains, Escherichia coli slowly started to grow toward the sink strainers, growing 1 inch each day, researchers found in a study.

High Rates of MDR <i>Enterobacteriaceae</i> Seen in Children

High Rates of MDR Enterobacteriaceae Seen in Children

Antibiotic-resistant Enterobacteriaceae bacterial infections up 700% in US children since 2007.

FDA Approves Procalcitonin Biomarker Test to Aid Antibiotic Decision Making

FDA Approves Procalcitonin Biomarker Test to Aid Antibiotic Decision Making

By

Test uses procalcitonin as a biomarker to help make antibiotic management decisions in patients with lower respiratory tract infections and sepsis.

MDR Organism Isolation Precaution Infrequently Used in Nursing Home Residents

MDR Organism Isolation Precaution Infrequently Used in Nursing Home Residents

Of the nursing homes reporting multidrug-resistant organism infection in the past year, 31% used isolation at least once among residents with multidrug-resistant organism infection.

High Rate of Metronidazole Resistance Seen in <i>C difficile</i> Infection

High Rate of Metronidazole Resistance Seen in C difficile Infection

By

Antibiotic resistance to therapies for Clostridium difficile infection are common, and their patterns should be considered in algorithms designed to select therapies.

Restricting Fluoroquinolone Use Helped With CDI Decline in England

Restricting Fluoroquinolone Use Helped With CDI Decline in England

The outbreak of Clostridium difficile in England that began in 2006 was curbed by reducing the use of fluoroquinolones, according to a study.

Injectable Antibiotic Drug Recalled

Injectable Antibiotic Drug Recalled

By

Hospira announced a voluntary recall of one lot of Vancomycin HCl for Injection, USP, after a confirmed report of particulate matter discovered in a single vial.

Carbapenem-Resistant Enterobacteriaceae Widespread in US Hospitals

Carbapenem-Resistant Enterobacteriaceae Widespread in US Hospitals

Carbapenem-resistant Enterobacteriaceae (CRE) causes roughly 9300 infections each year.

Superbug Resistant to All Available Antimicrobials

Superbug Resistant to All Available Antimicrobials

By

A Nevada woman was found to be infected with a pan-resistant superbug.

Sign Up for Free e-newsletters