antimicrobial resistance

Penicillin Allergies: Commonly Reported but Rarely Accurate

Penicillin Allergies: Commonly Reported but Rarely Accurate

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As infections from drug-resistant microbes continue to rise, the development of new antibiotics has declined since the golden age of antibiotic discovery in the mid-20th century.

ASM Microbe 2018 Update: Preserving Gram-Negative Antibiotics Through Better Diagnostics

ASM Microbe 2018 Update: Preserving Gram-Negative Antibiotics Through Better Diagnostics

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Neil Clancy, MD, from the VA Pittsburgh Health Care System, shares highlights from ASM Microbe 2018.

Relapse-Free Cure From MDR-TB Higher Than Anticipated

Relapse-Free Cure From MDR-TB Higher Than Anticipated

The frequency of relapse-free cure from multidrug-resistant tuberculosis is higher than previously anticipated.

New Designation for Some Gram-Negative Bacteremia Increases Treatment Options

New Designation for Some Gram-Negative Bacteremia Increases Treatment Options

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Nonsusceptibility to first-line antibiotics is associated with decreased survival in gram-negative bloodstream infections.

Examining the Prevalence of Prescribing Contraindicated Antimicrobials

Examining the Prevalence of Prescribing Contraindicated Antimicrobials

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Researchers performed a cross-sectional study that included multiple year pooled data (2003 to 2011) from the National Ambulatory Medical Care Survey and the National Hospital Ambulatory Medical Care Survey.

Some Bacteria Now More Tolerant of Alcohol-Based Sanitizers

Some Bacteria Now More Tolerant of Alcohol-Based Sanitizers

Some types of bacteria are developing tolerance of alcohol-based hand sanitizers used in hospitals.

Prevalence of Resistant Urinary Tract Infections Outpacing Antimicrobial Treatment

Prevalence of Resistant Urinary Tract Infections Outpacing Antimicrobial Treatment

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Approximately 6% of all patients presenting at an emergency department during a one year period with a UTI were diagnosed with an ESBL-producing Enterobacteriaceae infection.

Rapid Expansion of Multidrug Resistant <i>E. Coli</i> Clone ST1193 in the United States

Rapid Expansion of Multidrug Resistant E. Coli Clone ST1193 in the United States

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A new multi-drug resistant clone of Escherichia coli — ST1193 — has emerged in multiple US cities.

Antibiotic Selection Pressure Causally Linked to Macrolide Resistome

Antibiotic Selection Pressure Causally Linked to Macrolide Resistome

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Communities randomly assigned to less frequent antibiotic use had significantly lower prevalence of genetic antibiotic resistance determinants.

No Reduction in Antibiotic Use With Procalcitonin-Guided Therapy in the ED

No Reduction in Antibiotic Use With Procalcitonin-Guided Therapy in the ED

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Procalcitonin-guided therapy did not reduce the number of antibiotic prescriptions among patients presenting to the ED with fever.

Generic Quality Indicators Developed for Responsible Antibiotic Usage

Generic Quality Indicators Developed for Responsible Antibiotic Usage

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A study was conducted with a goal of developing a set of generic quality indicators for the safe and appropriate use of antibiotic agents.

Resistant <i>A Baumannii</i> Rose in Children From 1999 to 2012

Resistant A Baumannii Rose in Children From 1999 to 2012

Between 1999 and 2012, Acinetobacter baumannii antibiotic resistance increased in children.

Ibuprofen Inferior to Pivmecillinam for Uncomplicated UTI in Women

Ibuprofen Inferior to Pivmecillinam for Uncomplicated UTI in Women

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A study evaluated whether uncomplicated UTIs in women could be treated without antibiotics.

Empirical Use of Antibiotics for Resistant Infections Not Associated With Survival

Empirical Use of Antibiotics for Resistant Infections Not Associated With Survival

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Researchers found no association between starting colistin before final culture results and survival at 14 and 28 days.

Macrolides for Asthma Management: An Updated Review

Macrolides for Asthma Management: An Updated Review

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While macrolides had no direct effect on lung function, their use significantly improved asthma control and quality of life in patients with asthma.

Removing Low-Risk Penicillin Allergy Label Leads to Healthcare Cost Savings

Removing Low-Risk Penicillin Allergy Label Leads to Healthcare Cost Savings

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Children deemed low risk who were tested for penicillin allergy tolerated the medication within the following year without serious adverse or allergic reactions.

Kidney Stones Linked to Oral Antibiotics

Kidney Stones Linked to Oral Antibiotics

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Use of certain antibiotics may be contributing to the rise of kidney stones among children and adults.

IV Combo Antibiotic Recalled Due to Potential for Decreased Potency

IV Combo Antibiotic Recalled Due to Potential for Decreased Potency

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The 36 recalled lots were manufactured by Hospira and marketed by Apotex.

UTI Treatment Success in Women Greater With Nitrofurantoin vs Fosfomycin

UTI Treatment Success in Women Greater With Nitrofurantoin vs Fosfomycin

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Five-day nitrofurantoin may be a better alternative than single-dose fosfomycin for treating uncomplicated UTI in women.

Antibiotic Cycling, Mixing Does Not Prevent Gram-Negative Antibiotic Resistance

Antibiotic Cycling, Mixing Does Not Prevent Gram-Negative Antibiotic Resistance

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Findings do not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods, with third-generation or fourth-generation cephalosporins, piperacillin-tazobactam, and carbapenems reduces the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.

Critical Need to Reduce Pediatric Prophylactic Antimicrobial Prescriptions Worldwide

Critical Need to Reduce Pediatric Prophylactic Antimicrobial Prescriptions Worldwide

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Cross-sectional survey represents the first assessment of antimicrobial prescription practices for prophylaxis in pediatric patients hospitalized worldwide.

It Costs $2.2 Billion a Year to Treat Antibiotic Resistance

It Costs $2.2 Billion a Year to Treat Antibiotic Resistance

The need for innovative new infection prevention programs, antibiotics, and vaccines to prevent and treat antibiotic-resistant infections is an international priority.

CDC: Aggressive Action Needed to Contain Antibiotic Resistance

CDC: Aggressive Action Needed to Contain Antibiotic Resistance

Early aggressive action should be taken to prevent the spread of bacteria harboring unusual resistance genes.

Antibiotics, Acid-Suppressive Medications Tied to Allergic Disease

Antibiotics, Acid-Suppressive Medications Tied to Allergic Disease

The use of acid-suppressive medications and antibiotics during the first 6 months of infancy is tied to subsequent development of allergic disease.

Role of Vaccines in the Fight Against Antimicrobial Resistance

Role of Vaccines in the Fight Against Antimicrobial Resistance

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The potential role of vaccinations in combatting antimicrobial resistance (AMR) is currently undervalued. The distribution and development of new vaccines should be priorities in efforts to address the AMR crisis.

Combating Medically Important Antibiotic Use in Food-Producing Animals

Combating Medically Important Antibiotic Use in Food-Producing Animals

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The new WHO guidelines restricts antibiotic use in animals for purposes of growth promotion as well as avoidance of use for disease prevention.

Antibiotic Rotation in ICU Does Not Reduce Prevalence of Antibiotic-Resistant Bacteria

Antibiotic Rotation in ICU Does Not Reduce Prevalence of Antibiotic-Resistant Bacteria

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Findings from the study did not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods reduced the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.

Effectiveness of Meropenem-Vaborbactam for Complicated UTI Treatment

Effectiveness of Meropenem-Vaborbactam for Complicated UTI Treatment

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Evaluating treatment with meropenem/vaborbactam to piperacillin-tazobactam in patients with complicated UTIs.

FDA: Clarithromycin May Increase Long-Term Risk for Heart Problems, Death

FDA: Clarithromycin May Increase Long-Term Risk for Heart Problems, Death

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The recommendation was made after the FDA reviewed the results of a 10-year follow-up of the CLARICOR trial, which investigated the effects of clarithromycin in patients with stable coronary heart disease.

Characteristics Associated With Inappropriate Antibiotic Prescribing

Characteristics Associated With Inappropriate Antibiotic Prescribing

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Investigators identified patient, provider, and practice characteristics associated with antibiotic prescribing in an attempt to determine factors contributing to inappropriate antimicrobial use.

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