In high-income countries, the need for second-line treatments due to the development of acquired drug resistance will increase only slightly under the new ART initiation guidelines.
In patients living with HIV receiving TDF with a ritonavir-boosted protease inhibitor, the risk of CKD may be increased.
Dr Gianella Weibel talks with Dr Li and Dr Dubé, investigators of a new study from the AIDS Clinical Trials Group, which uses an intensively monitored antiretroviral pause to identify changes in HIV reservoirs after anti-HIV medications are stopped.
Study suggests that early initiation of combination antiretroviral therapy and full viral suppression may preserve long-term brain health.
The GRADE framework recommendations provide guidance for combination treatment regimens based on 2 systemic reviews, patient considerations, fetal outcomes, and practical issues.
Abacavir-containing antiretroviral therapy does not appear to confer an increased risk for myocardial infarction or coronary artery disease.
Researchers aim to identify changes in blood lipid profiles among children with HIV after 12 months of using antiretroviral therapy.
Learn more about when stopping antiretroviral therapy (ART) may be necessary, why patients discontinue ART, predicting viral suppression, and predicting and encouraging adherence.
The combination of tenofovir disoproxil fumarate, emtricitabine, and efavirenz was associated with the lowest risk of adverse birth outcome compared to other ART treatments.
Researchers aimed to reduce incidence of hypertriglyceridemia in people with HIV undergoing cART.
Tumors, such as acute lymphocytic leukemia, cancer of the tongue, and cancer of the penis, are becoming more common in the HAART era compared with the pre-HAART era.
Point-of-care testing of HIV-exposed infants at birth yielded results comparable to the standard of care laboratory-based testing and reduced time to result and time to antiretroviral therapy initiation.
One-week amphotericin plus flucytosine was found to have comparable efficacy and safety profiles as the standard of care, 2-weeks amphotericin-based therapy, for treatment of HIV-associated cryptococcal meningitis in African patients.
A child who was diagnosed with HIV at 1 month and received early treatment has suppressed the virus without anti-HIV therapy for 8.5 years.
New WHO guidelines address the issue of how to manage pretreatment human immunodeficiency virus drug resistance (HIVDR) in countries where the prevalence of HIVDR is 10% or higher.
The combination of long-acting intramuscular cabotegravir plus rilpivirine was demonstrated to be as effective as 3-drug daily oral ART for maintaining viral suppression of HIV-1 for up to 96 weeks in the LATTE-2 phase 2b study.
Several technological advances have been developed to improve adherence to antiretroviral and preexposure prophylaxis therapy.
Outcomes for HIV-positive patients are worse if they're on a PI-based vs non-PI-based ART regimen.
Early antiretroviral therapy initiation may increase the rate of bone loss in HIV patients.
Antiretroviral therapy may be the most consistent determinant of diabetes in patients with HIV.
Decreases were found in the prevalence of advanced disease at initiation of antiretroviral therapy (ART) in 10 high-burden countries.
More Americans with HIV are adhering to antiretroviral therapy regimens.
Study looks at the decay of HIV viral load in the genital tract by comparing the effect of different drug families on treatment-naive HIV-infected patients.
Young adult patients with HIV who are on treatment are living longer in North America and Europe.
Mother-to-child HIV transmission rates are low in the presence of antiretroviral therapy but increase once ART stops at 6 months postpartum.
Researchers assessed whether bone ultrasonography parameters were altered with a tenofovir treatment regimen compared to other antiretroviral drugs.
HIV poses higher risks of heart failure even at younger ages of infection, and 25% of all new cases in the United States occur in people between age 13 and 24.
Different HIV transmission dynamics are emerging, and the role of race/ethnicity and partnering patterns in the epidemic is becoming more apparent.
No difference in warfarin requirements seen in HIV-infected and HIV-uninfected patients with venous thrombosis.
Moderate diet-induced weight loss has important therapeutic cardiometabolic effects in HIV-positive women with obesity.
Sign Up for Free e-newsletters
Infectious Disease Advisor Articles
- Climate Change: Effects on the Incidence and Distribution of Infectious Diseases
- Improving Campaigns Regarding the Value of Adult Vaccines
- Seminal HPV Infection Prevalent Worldwide, May Affect Male Fertility
- Pausing ART to Identify Biomarkers for HIV RNA Rebound: Safety and Ethical Considerations
- MicroRNAs in Infectious Disease: Emerging Clinical Applications
- Efficacy of Direct-Acting Antivirals for HCV Clearance in Older Adults
- SVR Achieved With Sofosbuvir, Grazoprevir/Elbasvir Plus Ribavirin in HCV
- First Oral Smallpox Treatment Submitted to FDA for NDA
- Trends in Meningococcal Disease Following MenACWY Vaccine Introduction
- Clinician Accuracy Evaluated for Lyme Disease