Dermatology

Guidelines for Preventing Infections in Adolescent Athletes

Guidelines for Preventing Infections in Adolescent Athletes

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Many of the recommendations by sports organizations are more stringent than ordinary infection control practices for similar conditions.

Delafloxacin: Tolerable, Effective Against Gram-Negative Pathogens for ABSSSI

Delafloxacin: Tolerable, Effective Against Gram-Negative Pathogens for ABSSSI

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Delafloxacin is effective against gram-negative pathogens and has a similar tolerability profile to vancomycin/aztreonam when used in patients with an ASSSSI.

Delafloxacin is Effective, Safe for MRSA Treatment in ABSSSI

Delafloxacin is Effective, Safe for MRSA Treatment in ABSSSI

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Fixed dose delafloxacin IV/oral monotherapy was comparable to vancomycin/aztreonam in patients with ABSSSI and gram-positive pathogens.

No Difference in Adverse Events Between Delafloxacin or Vancomycin/Aztreonam in ABSSSI

No Difference in Adverse Events Between Delafloxacin or Vancomycin/Aztreonam in ABSSSI

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Incidence of adverse events with delafloxacin (Baxdela™, Melinta Therapeutics) was comparable to the combination regimen of vancomycin plus aztreonam across 2 phase 3 registrational ABSSSI studies.

Herpes Zoster Risk Greatly Increased in Psoriasis

Herpes Zoster Risk Greatly Increased in Psoriasis

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An increased risk of herpes zoster was found in women, elderly patients, and patients with psoriasis.

Antibiotic Prophylaxis May Help Prevent Recurrent Cellulitis

Antibiotic Prophylaxis May Help Prevent Recurrent Cellulitis

The recurrence of cellulitus can be prevented by antibiotic prophylaxis.

Risk of Herpes Zoster Increased With TNFi Treatment in RA Patients

Risk of Herpes Zoster Increased With TNFi Treatment in RA Patients

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Patients with rheumatoid arthritis receiving tumor necrosis factor inhibitors or using corticosteroids were significantly more likely to have herpes zoster.

Dust Mites May Be Carriers for Bacteria Causing IgE Sensitization in Dermatitis

Dust Mites May Be Carriers for Bacteria Causing IgE Sensitization in Dermatitis

House dust mites may act as carriers for immunoglobulin E sensitization to microbial antigens for patients with atopic dermatitis.

Scalp Nodularity Associated With Secondary Syphilis

Scalp Nodularity Associated With Secondary Syphilis

A rare case of secondary syphilis which primarily presented with multiple nodules on the scalp has been detailed in a case report.

Short-Term Outcomes in Small Skin Abscesses Improve With Antibiotics

Short-Term Outcomes in Small Skin Abscesses Improve With Antibiotics

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Patients with a simple abscess who received TMP-SMX along with incision and drainage had improved short-term outcomes compared to those who just received incision and drainage.

Herpes Zoster Diagnosis May Increase Risk of Cardiovascular Events

Herpes Zoster Diagnosis May Increase Risk of Cardiovascular Events

The risk of a cardiovascular event may be increased with herpes zoster.

No Benefits Seen for Adjunctive Clindamycin in Cellulitis

No Benefits Seen for Adjunctive Clindamycin in Cellulitis

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Results from atrial of clindamycin in cellulitis cast doubt on hospital guidelines.

Herpes Zoster Diagnosis Increasing in Hospital Emergency Rooms

Herpes Zoster Diagnosis Increasing in Hospital Emergency Rooms

There have been an increase in number of emergency department visits and costs for HZ-related ER visits.

Herpes Zoster Risk May Increase With Common Rheumatoid Arthritis Drugs

Herpes Zoster Risk May Increase With Common Rheumatoid Arthritis Drugs

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Common rheumatoid arthritis drugs methotrexate and biologics may increase risk for herpes zoster.

New Penicillin G Dosing Schedule Improves Treatment for Erysipelas

New Penicillin G Dosing Schedule Improves Treatment for Erysipelas

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Frequent recurrence of erysipelas has been a major challenge to treatment. Investigators looked at adjustments to the dosing schedule to improve efficacy of an existing therapy.

FDA Approves New Intravenous, Oral Antibiotic for Skin Infections

FDA Approves New Intravenous, Oral Antibiotic for Skin Infections

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The FDA has approved delafloxacin (Baxdela™, Melinta Therapeutics), a new antibacterial drug to treat acute bacterial skin and skin structure infections.

Treating Uncomplicated Cellulitis: Is Adding TMP/SMX Beneficial?

Treating Uncomplicated Cellulitis: Is Adding TMP/SMX Beneficial?

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Adding trimethoprim-sulfamethoxazole to cephalexin treatment for cellulitis does not benefit outcomes compared to cephalexin alone.

<i>Helicobacter pylori</i> Eradication Leads to Improvement in Rosacea

Helicobacter pylori Eradication Leads to Improvement in Rosacea

Use of standard Helicobacter pylori eradication therapy is associated with improvement in rosacea.

Telavancin Efficacy Against Difficult-to-Treat Pathogens

Telavancin Efficacy Against Difficult-to-Treat Pathogens

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Theravance Biopharma announced positive results from 3 studies on Vibativ (telavancin), a lipoglycopeptide antibiotic.

High Rates of Antibiotic Resistance in Infected Diabetic Foot Ulcers

High Rates of Antibiotic Resistance in Infected Diabetic Foot Ulcers

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A carbapenem with vancomycin is the least resistant initial antibiotic combination to use in patients with an infected diabetic foot ulcer.

Is Antibiotic Treatment Effective in Children With Mild Eczema?

Is Antibiotic Treatment Effective in Children With Mild Eczema?

Researchers find use of antibiotics ineffective for mild clinically infected eczema in children.

VZV Vaccine Promising in Immunocompromised Patients With Herpes Zoster

VZV Vaccine Promising in Immunocompromised Patients With Herpes Zoster

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Phase 3 study looked at the safety, tolerability, efficacy, and immunogenicity of inactivated VZV Vaccine in recipients of auto-HSCT.

Intramuscular Flu Vaccination Recommended for Patients With Eczema

Intramuscular Flu Vaccination Recommended for Patients With Eczema

Patients with atopic dermatitis with S aureus had reduced immune response to intradermal influenza vaccination but not intramuscular vaccination.

Daptomycin Effective in Treating Serious Skin Infections in Children

Daptomycin Effective in Treating Serious Skin Infections in Children

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Intravenous daptomycin may be effective and well-tolerated in children, possibly providing an alternative treatment against methicillin-resistant Staphylococcus aureus (MRSA) skin infections in this patient population.

Optimizing Treatments in Obese Patients With SSTIs

Optimizing Treatments in Obese Patients With SSTIs

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When treating skin and soft tissue infections (SSTIs) in obese patients, the pharmacokinetic/pharmacodynamic approach offers important data and decision-making tools for optimizing regimens.

Generic Topical Antifungal Cream Launched by Dr. Reddy's

Generic Topical Antifungal Cream Launched by Dr. Reddy's

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The cream is a combination of polyene antifungal and corticosteroid and is indicated for the treatment of cutaneous candidiasis.

Generic Tygacil Antibacterial Injection Available

Generic Tygacil Antibacterial Injection Available

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Fresenius Kabi's genetic tigecycline injections will be available beginning in 2017.

Skin Infections From Drug Resistant <i>S aureus</i> Tied to Livestock

Skin Infections From Drug Resistant S aureus Tied to Livestock

A recent study found that hog workers in the North Carolina are developing skin infections from multidrug-resistant Staphylococcus aureus.

<i>Propionibacterium acnes</i> Triggers Inflammation, Acne

Propionibacterium acnes Triggers Inflammation, Acne

Understanding of the skin microbiome is crucial to developing new acne treatment methods.

Antibiotics After Incision and Drainage Effective for Uncomplicated Skin Infections

Antibiotics After Incision and Drainage Effective for Uncomplicated Skin Infections

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Clindamycin or TMP-SMX following I&D was more effective at curing Staphylococcus aureus infection in children and adults compared with placebo.

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