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MicroRNAs in Infectious Disease: Emerging Clinical Applications

MicroRNAs in Infectious Disease: Emerging Clinical Applications

MicroRNAs are currently under investigation for various clinical applications in infectious disease because of their role in host response to infection and effects on innate and adaptive immune pathways.

Diagnostics

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Rapid, Point-of-Care Tool for Identifying Onchocerciasis in L loa-Endemic Areas

Rapid, Point-of-Care Tool for Identifying Onchocerciasis in L loa-Endemic Areas

A test-and-not-treat strategy may help areas in which loiasis is endemic and onchocerciasis is hypoendemic so that individuals who are not at risk for serious adverse events are safely given ivermectin treatment.

HPV and Cytology Co-Testing Lowers Risk of Cervical Cancer

HPV and Cytology Co-Testing Lowers Risk of Cervical Cancer

Successive negative HPV and cytology co-testing is linked decrease risks of cervical cancer.

Update on Latent Tuberculosis Testing and Treatment

Update on Latent Tuberculosis Testing and Treatment

A representative from the California Department of Public Health discusses latent TB infection testing and treatment recommendations and reasons why US physicians have been slow to test for and treat for the condition.

Zika Virus Persists in Tears of Convalescent Patients

Zika Virus Persists in Tears of Convalescent Patients

Although detection of Zika virus from conjunctiva has been previously reported, presence of Zika virus RNA in conjunctiva at the late convalescent phase of the disease was not known.

Patients With Septic Thrombophlebitis Benefit From Follow-Up Blood Cultures

Patients With Septic Thrombophlebitis Benefit From Follow-Up Blood Cultures

In critical care setting, thrombophlebitis can develop as a consequence of invasive procedures and, in case of bacteremia, it might represent a suitable medium that sustains bacterial growth and subsequent persistent endovascular infection.

Multibiomarker-Based Sepsis Score Predicts 30-Day Mortality

Multibiomarker-Based Sepsis Score Predicts 30-Day Mortality

Results from this study are novel with respect to the combined use of leukocyte count, procalcitonin, interleukin-6, and paraoxonase-1 activity for mortality prediction.

When and How to Test for Lyme Disease, a Growing Threat

When and How to Test for Lyme Disease, a Growing Threat

Diagnosing Lyme disease can be difficult because symptoms vary from one person to another and can resemble symptoms of other infectious diseases spread by ticks.

Automated Molecular Assay Detects Drug-Resistant Tuberculosis

Automated Molecular Assay Detects Drug-Resistant Tuberculosis

An automated molecular assay can detect Mycobacterium tuberculosis with resistance to drugs directly from sputum specimens.

Increasing HCV Screening Using Electronic Health Record Prompts

Increasing HCV Screening Using Electronic Health Record Prompts

The rates of anti-HCV orders and tests were collected from 4 medical specialties within a 30 mile radius of University of Michigan, Ann Arbor campus.

Challenges in Diagnosing Tuberculous Meningitis

Challenges in Diagnosing Tuberculous Meningitis

Diagnosis of tuberculous meningitis is challenging, although new, next-generation rapid POC testing holds promise for greatly improved sensitivity. Shorter and more effective treatments are needed.

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