MicroRNAs are currently under investigation for various clinical applications in infectious disease because of their role in host response to infection and effects on innate and adaptive immune pathways.
Proadrenomedullin and procalcitonin have demonstrated superiority to C-reactive protein for predicting mortality and guiding antimicrobial therapy in critically ill patients with fever.
Delayed lactate measurement is associated with delayed antibiotic administration and increased mortality in patients with increased lactate levels.
Time to optimal antimicrobial therapy for positive blood cultures was assessed in a pediatric population.
With the advent of platform manufacturing technology, vaccines can be developed quickly to stop the spread of outbreaks.
Researchers conducted a literature review to assess the effectiveness and safety of procalcitonin to guide treatment in patients with known or suspected sepsis.
Researchers reported on the first outbreak of an Asian lineage of chikungunya virus in Aruba.
Increased circulating immature granulocytes at the acute phase of sepsis are linked to clinical worsening, especially when associated with T-cell lymphopenia.
Study identifies and validates a simple PCR-based test from accessible blood samples that predicts TB in heterogeneous African populations with intermediate to high TB burdens.
Lung ultrasound was more effective in diagnosing pediatric community-acquired pneumonia than chest radiography.
The SeptiCyteTM LAB may be an effective complementary diagnostic tool to clinical assessment of critically ill adult patients in discriminating between sepsis and noninfectious systemic inflammation syndrome.
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Infectious Disease Advisor Articles
- Clinicians Warn That Zika Virus May Still Be an Area of Concern for Travelers
- Inappropriate Prescribing of Antibiotics High in Urgent Care Centers
- Fixed-Dose Bictegravir Regimen: A Safe Alternative in Adults With HIV-1
- Point-Counterpoint: Should We Implement Needle Exchange Programs for the Prevention of Hepatitis C Virus?
- FDA: Vibrio parahaemolyticus Illnesses Tied to Fresh Crab Meat From Venezuela
- Universal Purchase Programs in the United States May Not Effectively Increase Vaccination Rates
- Tick-Caused Meat Allergy on the Rise in the United States
- Prognostic Biomarkers to Guide Antibiotic Therapy in Critically Ill Patients
- Sofosbuvir/Velpatavir Effective for HCV-Infected Liver Transplant Recipients
- Should Metronidazole Be Recommended for Mild Clostridium difficile Infections?
- Same-Day ART Initiation in HIV+ Pregnant Women Does Not Worsen Outcomes
- Novel Nanodiagnostic Panel May Reduce Empiric Antifungal Use in High-Risk Candidemia
- Antimicrobial Lock Solutions Are Cost-Effective for Preventing Central Line-Associated Bloodstream Infections
- Predictors of Influenza Vaccine Acceptance in Inflammatory Rheumatic Diseases
- Pegylated Interferon, Ribavirin May Improve LV Diastolic Dysfunction in Chronic Hepatitis C