MicroRNAs are currently under investigation for various clinical applications in infectious disease because of their role in host response to infection and effects on innate and adaptive immune pathways.
A test-and-not-treat strategy may help areas in which loiasis is endemic and onchocerciasis is hypoendemic so that individuals who are not at risk for serious adverse events are safely given ivermectin treatment.
Successive negative HPV and cytology co-testing is linked decrease risks of cervical cancer.
A representative from the California Department of Public Health discusses latent TB infection testing and treatment recommendations and reasons why US physicians have been slow to test for and treat for the condition.
Although detection of Zika virus from conjunctiva has been previously reported, presence of Zika virus RNA in conjunctiva at the late convalescent phase of the disease was not known.
In critical care setting, thrombophlebitis can develop as a consequence of invasive procedures and, in case of bacteremia, it might represent a suitable medium that sustains bacterial growth and subsequent persistent endovascular infection.
Results from this study are novel with respect to the combined use of leukocyte count, procalcitonin, interleukin-6, and paraoxonase-1 activity for mortality prediction.
Diagnosing Lyme disease can be difficult because symptoms vary from one person to another and can resemble symptoms of other infectious diseases spread by ticks.
An automated molecular assay can detect Mycobacterium tuberculosis with resistance to drugs directly from sputum specimens.
The rates of anti-HCV orders and tests were collected from 4 medical specialties within a 30 mile radius of University of Michigan, Ann Arbor campus.
Diagnosis of tuberculous meningitis is challenging, although new, next-generation rapid POC testing holds promise for greatly improved sensitivity. Shorter and more effective treatments are needed.
Echocardiography is used to diagnose infective endocarditis, but it is not known which patients with non-beta-hemolytic streptococci bacteremia should undergo echocardiography.
A rapid immunochromatography approach can differentiate dengue and Zika virus cases
Antimicrobial stewardship traditionally focuses on optimal use of antibacterial agents, not antifungal therapy.
Qiagen announced on October 5, 2017, the marketing of an improved blood test for tuberculosis infection.
The relationship between negative tuberculin skin test and in-hospital mortality has not been previously studied.
Compared to blood cultures, T2 Candida Panel is faster and more sensitive in detecting Candidemia.
Pediatric patients with group A streptococcal pharyngitis should not be treated with antibiotics if results of an RADT are negative.
The parameters of the complete blood cell count, WBC, ANC and platelet count were used to test accuracy in identifying infants with invasive bacterial infections.
This new risk score may guide the identification of high-risk people who would benefit from preventative measures.
Time to blood culture positivity was directly associated with disease severity and outcomes in bacteremic pneumococcal pneumonia.
Experts discuss screening, treatment, and other considerations in pediatric HCV.
The quick Sepsis-Related Organ Failure Assessment (qSOFA) clinical tool was superior to SIRS criteria for the evaluation of in-hospital mortality.
Point-of-Care Tests for HIV and T pallidum Infections: Utility of Smartphone-Based Electronic ReaderSeptember 08, 2017
A smartphone-based electronic reader with dual point of care tests were evaluated in the detection of antibodies to T pallidum and HIV.
Rapid HIV testing offered to patients in addition to a clinician consultation increases the testing rate in the emergency department.
A new organ dysfunction scoring system that predicts in-hospital mortality was validated in critically ill children admitted to the pediatric intensive care unit.
A change of QuantiFERON-TB interferon (IFN)γ values could improve tuberculosis detection.
The CDC systematic review follows a trend of clinicians offering more frequent HIV screening to gay, bisexual, and other men who have sex with men, but the evidence is insufficient to warrant a change to the current recommendations.
The FDA issued an Emergency Use Authorization for the Center for Infection and Immunity-ArboViroPlex rRT-PCR Test for Zika virus detection.
Point-of-care testing of HIV-exposed infants at birth yielded results comparable to the standard of care laboratory-based testing and reduced time to result and time to antiretroviral therapy initiation.
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Infectious Disease Advisor Articles
- Climate Change: Effects on the Incidence and Distribution of Infectious Diseases
- Improving Campaigns Regarding the Value of Adult Vaccines
- Seminal HPV Infection Prevalent Worldwide, May Affect Male Fertility
- Pausing ART to Identify Biomarkers for HIV RNA Rebound: Safety and Ethical Considerations
- MicroRNAs in Infectious Disease: Emerging Clinical Applications
- Efficacy of Direct-Acting Antivirals for HCV Clearance in Older Adults
- SVR Achieved With Sofosbuvir, Grazoprevir/Elbasvir Plus Ribavirin in HCV
- First Oral Smallpox Treatment Submitted to FDA for NDA
- Trends in Meningococcal Disease Following MenACWY Vaccine Introduction
- Clinician Accuracy Evaluated for Lyme Disease