Diagnostics

The T2Candida Panel Has Decreased Time to Therapy Initiation for Candidemia

The T2Candida Panel Has Decreased Time to Therapy Initiation for Candidemia

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Antimicrobial stewardship traditionally focuses on optimal use of antibacterial agents, not antifungal therapy.

Tuberculosis Diagnosis: Improved Blood Test by Qiagen to Hit Shelves

Tuberculosis Diagnosis: Improved Blood Test by Qiagen to Hit Shelves

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Qiagen announced on October 5, 2017, the marketing of an improved blood test for tuberculosis infection.

Accuracy of Negative Tuberculin Skin Test in Predicting In-Hospital Tuberculosis  Mortality

Accuracy of Negative Tuberculin Skin Test in Predicting In-Hospital Tuberculosis Mortality

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The relationship between negative tuberculin skin test and in-hospital mortality has not been previously studied.

T2 Candida Panel is Superior to Blood Cultures for Identifying Candidemia

T2 Candida Panel is Superior to Blood Cultures for Identifying Candidemia

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Compared to blood cultures, T2 Candida Panel is faster and more sensitive in detecting Candidemia.

Antibiotics Not Recommended in Pediatrics With Negative Rapid Strep Test Results

Antibiotics Not Recommended in Pediatrics With Negative Rapid Strep Test Results

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Pediatric patients with group A streptococcal pharyngitis should not be treated with antibiotics if results of an RADT are negative.

Risk Stratification in Febrile Infants Using Complete Blood Cell Counts

Risk Stratification in Febrile Infants Using Complete Blood Cell Counts

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The parameters of the complete blood cell count, WBC, ANC and platelet count were used to test accuracy in identifying infants with invasive bacterial infections.

Risk for TB Infection Predicted by New Scoring System

Risk for TB Infection Predicted by New Scoring System

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This new risk score may guide the identification of high-risk people who would benefit from preventative measures.

Time to Blood Culture Positivity Predicts Pneumonia Severity and Outcome

Time to Blood Culture Positivity Predicts Pneumonia Severity and Outcome

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Time to blood culture positivity was directly associated with disease severity and outcomes in bacteremic pneumococcal pneumonia.

Update on Pediatric HCV: Screening, Treatment, and Other Considerations

Update on Pediatric HCV: Screening, Treatment, and Other Considerations

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Experts discuss screening, treatment, and other considerations in pediatric HCV.

Clinical Update: Community-Acquired Pneumonia Following Sepsis

Clinical Update: Community-Acquired Pneumonia Following Sepsis

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The quick Sepsis-Related Organ Failure Assessment (qSOFA) clinical tool was superior to SIRS criteria for the evaluation of in-hospital mortality.

Point-of-Care Tests for HIV and T pallidum Infections: Utility of Smartphone-Based Electronic Reader

Point-of-Care Tests for HIV and T pallidum Infections: Utility of Smartphone-Based Electronic Reader

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A smartphone-based electronic reader with dual point of care tests were evaluated in the detection of antibodies to T pallidum and HIV.

Offering Rapid HIV Testing in EDs Increase Testing Rates

Offering Rapid HIV Testing in EDs Increase Testing Rates

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Rapid HIV testing offered to patients in addition to a clinician consultation increases the testing rate in the emergency department.

New Scoring System Predicts In-Hospital Mortality in Critically Ill Children With Sepsis

New Scoring System Predicts In-Hospital Mortality in Critically Ill Children With Sepsis

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A new organ dysfunction scoring system that predicts in-hospital mortality was validated in critically ill children admitted to the pediatric intensive care unit.

Tuberculosis Detection Could Improve With Conversion Value Change

Tuberculosis Detection Could Improve With Conversion Value Change

A change of QuantiFERON-TB interferon (IFN)γ values could improve tuberculosis detection.

CDC: No Evidence to Encourage More Frequent HIV Screening in MSM

CDC: No Evidence to Encourage More Frequent HIV Screening in MSM

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The CDC systematic review follows a trend of clinicians offering more frequent HIV screening to gay, bisexual, and other men who have sex with men, but the evidence is insufficient to warrant a change to the current recommendations.

FDA Issues Emergency Use Authorization for Multiplex Zika Virus Test

FDA Issues Emergency Use Authorization for Multiplex Zika Virus Test

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The FDA issued an Emergency Use Authorization for the Center for Infection and Immunity-ArboViroPlex rRT-PCR Test for Zika virus detection.

Point-of-Care Testing of HIV-Exposed Infants Improves Linkage to Care

Point-of-Care Testing of HIV-Exposed Infants Improves Linkage to Care

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Point-of-care testing of HIV-exposed infants at birth yielded results comparable to the standard of care laboratory-based testing and reduced time to result and time to antiretroviral therapy initiation.

Better Diagnostics Needed for Milder HIV-Associated Neurocognitive Disorders

Better Diagnostics Needed for Milder HIV-Associated Neurocognitive Disorders

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In order to assess and manage milder forms of HIV-associated neurocognitive disorders, effective cognitive screening instruments are needed.

Eye Abnormalities May Be First Sign of Congenital Zika Virus Infection

Eye Abnormalities May Be First Sign of Congenital Zika Virus Infection

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Infants exposed to the Zika virus in utero should have their eyes examined for possible virus-related abnormalities.

CMV Infection in Mothers and Infants: Diagnostic and Treatment Challenges

CMV Infection in Mothers and Infants: Diagnostic and Treatment Challenges

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Cytomeglovirus infection is associated with a range of diagnostic and treatment challenges and a relatively high transmission rate from the mother to the fetus.

Diagnosing Rhinosinusitis Using Clinical Decision Rules

Diagnosing Rhinosinusitis Using Clinical Decision Rules

Clinical decision rules can be used to diagnose acute rhinosinusitis and acute bacterial rhinosinusitis.

Increased Incidence of Chlamydia Due to Changes in Cancer Screening Guidelines

Increased Incidence of Chlamydia Due to Changes in Cancer Screening Guidelines

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Recent cervical cancer screening guideline changes in Canada were associated with reduced chlamydia testing and reported new cases of chlamydia in women.

New Criteria Needed For Infection Diagnosis Among Elderly in ER

New Criteria Needed For Infection Diagnosis Among Elderly in ER

A study published in the Journal of American Geriatrics Society calls for a new criteria for diagnosing infection among elderly in the emergency department.

Can Testing Placental Tissue Confirm Zika Infection?

Can Testing Placental Tissue Confirm Zika Infection?

Zika infection can be ruled out or confirmed by testing fetal and placental tissue according to a study published in Morbidity and Mortality Weekly Report.

Point-of-Care Test for Active Hepatitis C Virus Infection

Point-of-Care Test for Active Hepatitis C Virus Infection

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Point-of-care test was found to have high sensitivity and specificity for detecting HCV RNA in both capillary whole-blood samples collected by finger stick and in plasma samples collected by venipuncture.

Sepsis-Related Mortality Decreased With Rapid Implementation of Protocol

Sepsis-Related Mortality Decreased With Rapid Implementation of Protocol

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Rapid treatment of sepsis using mandated care bundles improves outcomes.

Advances in Point-of-Care Testing and Tips for Clinicians

Advances in Point-of-Care Testing and Tips for Clinicians

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An expert interview on recent developments in molecular point-of-care and near-patient testing for infectious diseases.

New Assay Targets Susceptibility to Ciprofloxacin in Gonorrhea

New Assay Targets Susceptibility to Ciprofloxacin in Gonorrhea

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In an effort to combat extensive drug-resistance in gonorrhea, a new assay identifies patients who may still have a response to an older, less reliable therapy.

Designer Protein Halts Influenza Virus From Infecting Cells

Designer Protein Halts Influenza Virus From Infecting Cells

A designer protein stopped the influenza virus from infecting cells in culture and protected mice after being exposed to heavy doses of the virus, according to a new study.

OpenArray PCR Platform Can Be Adapted to Discriminate Emerging Pathogens

OpenArray PCR Platform Can Be Adapted to Discriminate Emerging Pathogens

The OpenArray polymerase chain reaction platform can detect and discriminate agents in plasma and blood samples.

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