Emerging Diseases

Fever, Rash, Conjunctival Hyperemia Common Symptoms of Pediatric Zika Virus Infection

Fever, Rash, Conjunctival Hyperemia Common Symptoms of Pediatric Zika Virus Infection

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Symptomatic pediatric patients infected with Zika virus generally have a mild, often nonspecific symptoms not requiring hospitalization.

Fever, Rash, Erythema Seen in Most Puerto Rican Kids Infected With Zika Virus

Fever, Rash, Erythema Seen in Most Puerto Rican Kids Infected With Zika Virus

Most children with Zika virus (ZIKV) infection have fever, rash, and facial or neck erythema.

Platform Manufacturing May Speed Pandemic Vaccine Development

Platform Manufacturing May Speed Pandemic Vaccine Development

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With the advent of platform manufacturing technology, vaccines can be developed quickly to stop the spread of outbreaks.

Single-Dose Ebola Vaccine Durable for 1 to 2 Years

Single-Dose Ebola Vaccine Durable for 1 to 2 Years

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Study provides new data on the durability of the humoral immune response up to 2 years after single-dose injection with rVSV-ZEBOV vaccine in a population of primarily European ancestry, and additional data on durability at 1 year after vaccination in 2 African populations.

Zika Virus RNA Often Identified in Semen of Men With Symptomatic Infection

Zika Virus RNA Often Identified in Semen of Men With Symptomatic Infection

Zika virus RNA is frequently present in the semen of men with symptomatic ZIKV infection and can persist for over 6 months.

Pregnancy May Be Independently Associated With Prolonged Detection of Zika Virus RNA

Pregnancy May Be Independently Associated With Prolonged Detection of Zika Virus RNA

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Pregnant women may have about a 3-fold longer estimated median detection window for Zika virus RNA in serum.

An Effective Zika Vaccine May Eliminate Prenatal Infections

An Effective Zika Vaccine May Eliminate Prenatal Infections

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A vaccine against Zika virus, once available and effectively deployed, may substantially reduce prenatal infections.

A Zika vaccine could virtually eliminate prenatal infections

A Zika virus vaccine shown to be of moderate to high efficacy in eliminating prenatal infections provides 90% coverage.

Rate of Birth Defects in Pregnant Women With Confirmed Zika Virus Infection

Rate of Birth Defects in Pregnant Women With Confirmed Zika Virus Infection

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Researchers estimated this risk among pregnant women with symptomatic Zika virus infection in French territories in the Americas.

Zika Virus-Associated Neurogenic Bladder Requires Prompt Management

Zika Virus-Associated Neurogenic Bladder Requires Prompt Management

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Prompt identification may help reduce the risk for subsequent renal failure and minimize overall disease burden.

Multistate Outbreak of <i>Salmonella</i> Linked to Popular Herbal Drug

Multistate Outbreak of Salmonella Linked to Popular Herbal Drug

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Kratom, the controversial plant used by some as an opioid substitute, is at the center of a multistate Salmonella outbreak, prompting the CDC to issue a recommendation against the consumption of kratom in any form.

Evidence of Postnatal Zika Virus Transmission From Breast Milk

Evidence of Postnatal Zika Virus Transmission From Breast Milk

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Although Zika virus is known to be transmitted by mosquitos, sexual contact, blood transfusion, or laboratory exposure, there is also evidence supporting maternal transmission to infants via breastfeeding, delivery, or close contact.

Microcephaly rates elevated in Brazil prior to Zika virus epidemic

Microcephaly was associated with lack of maternal schooling, living without a partner, smoking during pregnancy, intrauterine growth restriction, vaginal delivery, and the pregnancy being the mother's first.

Climate Change: Effects on the Incidence and Distribution of Infectious Diseases

Climate Change: Effects on the Incidence and Distribution of Infectious Diseases

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Without proactive measures and response, the changing climate is projected to continue to adversely affect the global incidence and distribution of infectious diseases and cause 250,000 additional deaths per year between 2030 and 2050.

Rapid, Point-of-Care Tool for Identifying Onchocerciasis in <i>L loa</i>-Endemic Areas

Rapid, Point-of-Care Tool for Identifying Onchocerciasis in L loa-Endemic Areas

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A test-and-not-treat strategy may help areas in which loiasis is endemic and onchocerciasis is hypoendemic so that individuals who are not at risk for serious adverse events are safely given ivermectin treatment.

Growing Body of Evidence Links Zika Virus With Guillain-Barré Syndrome

Growing Body of Evidence Links Zika Virus With Guillain-Barré Syndrome

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Evidence suggests a link between the Zika virus infection and Guillain-Barré Syndrome.

Multidrug-Resistant <i>Salmonella</i> Strains Emerging in United States

Multidrug-Resistant Salmonella Strains Emerging in United States

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Analysis demonstrated that the differentiation into clades correlated more closely with the presence of an ASSuT genotype and certain MLST sequence types than with the geographic origin of the isolates.

Previous West Nile Virus Infection May Cause Neurologic Abnormalities

Previous West Nile Virus Infection May Cause Neurologic Abnormalities

Many patients with a previous West Nile virus infection have abnormalities on neurologic examination several years after they were infected.

Evidence-Based Guidelines for Supportive Care in Ebola Treatment

Evidence-Based Guidelines for Supportive Care in Ebola Treatment

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First-hand accounts of the care that was delivered during the 2013-16 West African outbreak of Ebola virus disease provided impetus for these guidelines.

Zika Virus Preferentially Infects, Kills Glioblastoma Stem Cells

Zika Virus Preferentially Infects, Kills Glioblastoma Stem Cells

The Zika virus preferentially targets glioblastoma stem cells.

CDC Guidance Update for Possible Congenital Zika Infection

CDC Guidance Update for Possible Congenital Zika Infection

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This updated interim guidance is based on current, limited data about Zika virus infection, and reflects the information available as of September 2017.

Rapid Antigen Test Differentiates Zika and Dengue Cases

Rapid Antigen Test Differentiates Zika and Dengue Cases

A rapid immunochromatography approach can differentiate dengue and Zika virus cases

Zika Infection May Lead to High Risk of Neurologic Complications

Zika Infection May Lead to High Risk of Neurologic Complications

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The Zika virus may be associated with a high risk for neurologic complications in affected adults.

Single Mutation Contributes to Fetal Microcephaly in Zika Virus

Single Mutation Contributes to Fetal Microcephaly in Zika Virus

A single serine to glutamin substitution (S139N) in the viral polyprotein substantially increased Zika virus infectivity in both human and mouse neural progenitor cells.

FDA Approves First Test for Detecting Zika in Blood Donations

FDA Approves First Test for Detecting Zika in Blood Donations

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Testing for Zika virus in blood products follows FDA recommendations for the screening of individual units of whole blood and blood components.

Congenital Zika, Cobalamin C Deficiency: Retinal Changes Evaluated With SD-OCT

Congenital Zika, Cobalamin C Deficiency: Retinal Changes Evaluated With SD-OCT

Retinal maldevelopment associated with congenital Zika syndrome is similar to the maldevelopment seen with cobalamin C deficiency.

Zika Virus Skews Immunosuppression During Pregnancy, Inducing Rapid Viremia

Zika Virus Skews Immunosuppression During Pregnancy, Inducing Rapid Viremia

The Zika virus thrives in pregnant women by suppressing their already dampened immune systems and running roughshod over their body's natural defenses.

Detection of Zika Virus RNA in Semen

Detection of Zika Virus RNA in Semen

The Zika virus might not last in the semen of infected men as long as previously thought.

Low Risk of Oropharangeal Zika Virus Transmission in Monkeys

Low Risk of Oropharangeal Zika Virus Transmission in Monkeys

Zika virus doesn't appear to be transmitted through saliva in rhesus monkeys.

FDA Issues Emergency Use Authorization for Multiplex Zika Virus Test

FDA Issues Emergency Use Authorization for Multiplex Zika Virus Test

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The FDA issued an Emergency Use Authorization for the Center for Infection and Immunity-ArboViroPlex rRT-PCR Test for Zika virus detection.

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