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Respiratory Challenges in Diagnosing Tuberculous Meningitis

Challenges in Diagnosing Tuberculous Meningitis

Diagnosis of tuberculous meningitis is challenging, although new, next-generation rapid POC testing holds promise for greatly improved sensitivity. Shorter and more effective treatments are needed.

Hepatitis Short-Duration Treatment Regimens for Chronic HCV: Latest Insights

Short-Duration Treatment Regimens for Chronic HCV: Latest Insights

The high cost of DAA-based regimens remains an ethical issue and an obstacle to treatment accessibility. Shorter treatment regimens may offer substantial cost savings, improved treatment adherence, and a reduced rate of side effects.

Hepatitis Challenges in Treating Genotype 3 Hepatitis C Virus

Challenges in Treating Genotype 3 Hepatitis C Virus

Data have shown patients with genotype 3 HCV have faster progression of fibrosis and higher rates of cirrhosis, severe steatosis, and hepatocellular carcinoma.

Waterborne Illnesses Typhoid Conjugate Vaccine Protective Against Oral Salmonella Typhi Challenge

Typhoid Conjugate Vaccine Protective Against Oral Salmonella Typhi Challenge

Investigators review results from the first study to assess the efficacy of a Vi-conjugate vaccine using a controlled human infection model of typhoid fever.

GI Illness Better Detection and Treatment Needed for H pylori Infections in Children

Better Detection and Treatment Needed for H pylori Infections in Children

In recent years, a link between childhood Helicobacter pylori and gastric cancer in adulthood has elevated the need to detect and treat H pylori in asymptomatic children.

Chlamydia Vaginal Microbiota Profile Predictive of Chlamydia Susceptibility

Vaginal Microbiota Profile Predictive of Chlamydia Susceptibility

Vaginal microbiota dominated by L iners has been shown to exhibit rapid change in composition in and out of community states similar to bacterial vaginosis.

Antibiotics, Antimicrobial Resistance Are Antibiotic Stewardship Programs the Antidote to Antibiotic Overuse?

Are Antibiotic Stewardship Programs the Antidote to Antibiotic Overuse?

Optimizing outcomes with an antibiotic stewardship programs requires a team approach that involves point-of-care providers.

Antibiotics, Antimicrobial Resistance Strategies for Preventing Antibiotic Resistance in Acne

Strategies for Preventing Antibiotic Resistance in Acne

Physicians can help avoid contributing to antibiotic resistance by recognizing and using appropriate alternative treatments, and having a strategy so that patients are not on antibiotics for a long period of time.

HIV/AIDS Assessing the Risk Factors of Neurocognitive Decline in HIV+ Individuals

Assessing the Risk Factors of Neurocognitive Decline in HIV+ Individuals

The incidence of neurocognitive impairment is high in HIV-infected population, despite the introduction of combination antiretroviral therapy (CART).

Influenza Link Between Influenza Vaccine, Spontaneous Abortion Further Clarified

Link Between Influenza Vaccine, Spontaneous Abortion Further Clarified

Pregnant women who received vaccines containing the pH1N1 antigen for 2 consecutive influenza seasons may have increased risk for spontaneous abortion 28 days postvaccination.

Hepatitis Treating Hepatocellular Carcinoma: A Fight Against the Odds

Treating Hepatocellular Carcinoma: A Fight Against the Odds

Despite continual efforts aimed at finding new treatment options, HCC still has a very low 5-year survival rate, less than 20%, as many patients are diagnosed at an advanced stage of the disease.

Skin Infections No Difference in Adverse Events Between Delafloxacin or Vancomycin/Aztreonam in ABSSSI

No Difference in Adverse Events Between Delafloxacin or Vancomycin/Aztreonam in ABSSSI

Incidence of adverse events with delafloxacin (Baxdela™, Melinta Therapeutics) was comparable to the combination regimen of vancomycin plus aztreonam across 2 phase 3 registrational ABSSSI studies.

Pneumonia Updated Guidelines for Management of Hospital-Acquired/Ventilator-Associated Pneumonia

Updated Guidelines for Management of Hospital-Acquired/Ventilator-Associated Pneumonia

An international panel of experts applied the GRADE system and choose 7 PICO questions to generate recommendations for HAP/VAP.

HIV/AIDS Why Patients Discontinue ART— and What You Can Do to Stop It

Why Patients Discontinue ART— and What You Can Do to Stop It

Learn more about when stopping antiretroviral therapy (ART) may be necessary, why patients discontinue ART, predicting viral suppression, and predicting and encouraging adherence.

Treatments Guideline-Adherent Antibiotics Decrease Readmission for Acute Chest Syndrome

Guideline-Adherent Antibiotics Decrease Readmission for Acute Chest Syndrome

Researchers believe implementation of treatment guidelines for children with sickle cell disease with acute chest syndrome may decrease hospital readmission rates.

Antibiotics, Antimicrobial Resistance Delafloxacin Shows High Response Rates in Fluoroquinolone-resistant S aureus

Delafloxacin Shows High Response Rates in Fluoroquinolone-resistant S aureus

New data confirms delafloxacin shows high response rates against MRSA.

HIV/AIDS Bone Loss and Fracture Risk in Patients With HIV: What We Know So Far

Bone Loss and Fracture Risk in Patients With HIV: What We Know So Far

In addition to prevention measures, switching off the ARTs associated with bone loss and administering intravenous bisphosphonate, a bone resorption inhibitor, can be an effective strategy for preventing bone loss seen in HIV-infected individuals.

Practice Management Ransomware Attacks in Medicine: Are Hospitals Adequately Protected?

Ransomware Attacks in Medicine: Are Hospitals Adequately Protected?

How can hospitals protect themselves against recent ransomware attacks?

Hepatitis Hepatitis B: Search for the Cure and Challenges That Remain

Hepatitis B: Search for the Cure and Challenges That Remain

One of the main challenges in managing and controlling hepatitis B infection today is identifying people who are infected and ensuring that they have access to suitable treatment.

Practice Management Accountable Care Organizations: Evaluating Cost Saving Success

Accountable Care Organizations: Evaluating Cost Saving Success

An analysis on the cost saving success of accountable care organizations.

Respiratory M tuberculosis Disrupts Regulatory Macrophage Pathways Driving Immunopathology

M tuberculosis Disrupts Regulatory Macrophage Pathways Driving Immunopathology

Mycobacterium tuberculosis engages the host immune response to drive immunopathology and tissue destruction by disrupting negative regulatory pathways in human macrophages.

Nosocomial Infections Follow-up Blood Culture in Gram-Negative Bacteremia Should Be Avoided

Follow-up Blood Culture in Gram-Negative Bacteremia Should Be Avoided

Follow-up blood cultures may have little utility in the management of Gram-negative bacilli bacteremia, according to data from a recent study.

GI Illness CDC Issues Advisory on the Rise of Cyclosporiasis

CDC Issues Advisory on the Rise of Cyclosporiasis

The CDC Health Alert Network has issued an advisory regarding an increase in cases of the intestinal illness cyclosporiasis.

Sexually Transmitted Diseases Mycoplasma genitalium: Challenges in Diagnosis and Treatment

Mycoplasma genitalium: Challenges in Diagnosis and Treatment

While Mycoplasma genitalium is emerging as one of the most common causes of sexually transmitted infections, and is often underrecognized and treated with ineffective antibiotics.

Vector-borne Illnesses Second Dose of Tetravalent Dengue Vaccine Candidate Shows Enhanced Immunogenicity

Second Dose of Tetravalent Dengue Vaccine Candidate Shows Enhanced Immunogenicity

A tetravalent dengue vaccine candidate (TDV) was found to be safe and immunogenic in an ongoing phase 2 trial. A second TDV dose induced enhanced immunogenicity against DENV-3 and DENV-4 in children who were seronegative before vaccination, supporting the initiation of phase 3 trial to evaluate the efficacy and safety of TDV given in a 2-dose schedule 3 months apart.

Clostridium Difficile Biotherapeutics for the Prevention of Clostridium difficile Infection

Biotherapeutics for the Prevention of Clostridium difficile Infection

Experts review biotherapeutics for the prevention of C difficile infection, including probiotics, fecal microbiota transplantation, and nontoxigenic C difficile.

Hepatitis Hepatitis C Virus Infection and Cardiovascular Disease Risk

Hepatitis C Virus Infection and Cardiovascular Disease Risk

Epidemiological data demonstrate a link between HCV infection and cardiovascular disease, whereas treatment studies suggest viral eradication may lower the risk for cardiovascular morbidity and mortality.

Pneumonia Challenges in Managing Hospital-Acquired Pneumonia

Challenges in Managing Hospital-Acquired Pneumonia

Diagnosis is one of the primary difficulties in managing hospital acquired pneumonia.

HIV/AIDS Amphotericin and Flucytosine Safe, Effective for HIV-Associated Cryptococcal Meningitis

Amphotericin and Flucytosine Safe, Effective for HIV-Associated Cryptococcal Meningitis

One-week amphotericin plus flucytosine was found to have comparable efficacy and safety profiles as the standard of care, 2-weeks amphotericin-based therapy, for treatment of HIV-associated cryptococcal meningitis in African patients.

Hepatitis New Treatment Options for Rheumatic Manifestations of HCV

New Treatment Options for Rheumatic Manifestations of HCV

Patients with HCV are at risk for several extrahepatic sequelae. Find out what they are and the new treatment options for managing HCV in patients with rheumatic symptoms.

Pediatric Illnesses CMV Infection in Mothers and Infants: Diagnostic and Treatment Challenges

CMV Infection in Mothers and Infants: Diagnostic and Treatment Challenges

Cytomeglovirus infection is associated with a range of diagnostic and treatment challenges and a relatively high transmission rate from the mother to the fetus.

HIV/AIDS ART and PrEP: How Technological Advances Can Improve Adherence

ART and PrEP: How Technological Advances Can Improve Adherence

Several technological advances have been developed to improve adherence to antiretroviral and preexposure prophylaxis therapy.

Ebola Ebola Vaccine Long-Term Safety and Antibody Response

Ebola Vaccine Long-Term Safety and Antibody Response

An Ebola virus vaccine, rVSVΔG-ZEBOV-GP, provided 100% protection against Ebola in a prior phase 3 trial. A new study reports long-term safety data and shows that the vaccine induces an antibody response for at least 1 year.

Infections in Immunocompromised Patients Infections Complicate Biologic Use in Autoimmune Inflammatory Disorders

Infections Complicate Biologic Use in Autoimmune Inflammatory Disorders

The risk for infection and malignancy associated with biologic use complicates the management of patients with a deficient immune system. Equip yourself with the information needed to effectively manage these complex patients.

Sepsis Sepsis-Related Mortality Decreased With Rapid Implementation of Protocol

Sepsis-Related Mortality Decreased With Rapid Implementation of Protocol

Rapid treatment of sepsis using mandated care bundles improves outcomes.

Diagnostics Advances in Point-of-Care Testing and Tips for Clinicians

Advances in Point-of-Care Testing and Tips for Clinicians

An expert interview on recent developments in molecular point-of-care and near-patient testing for infectious diseases.

Sexually Transmitted Diseases New Assay Targets Susceptibility to Ciprofloxacin in Gonorrhea

New Assay Targets Susceptibility to Ciprofloxacin in Gonorrhea

In an effort to combat extensive drug-resistance in gonorrhea, a new assay identifies patients who may still have a response to an older, less reliable therapy.

Geriatric Illnesses Gut Microbiota Associated With Parkinson's Disease Progression

Gut Microbiota Associated With Parkinson's Disease Progression

An imbalance in gut microbiota may be associated with the progression of Parkinson's disease.

HIV/AIDS Last Gift Study: A Participant's Perspective on End-of-Life HIV Research

Last Gift Study: A Participant's Perspective on End-of-Life HIV Research

Dr Sara Gianella Weibel talks with Anthony B, a patient with HIV and end-stage amyotrophic lateral sclerosis and the first participant enrolled in the "Last Gift" end-of-life study, about his experience as part of this new end-of-life model to study HIV persistence.

HIV/AIDS Last Gift Study: Community Perspective on End-of-Life HIV Research

Last Gift Study: Community Perspective on End-of-Life HIV Research

Dr Sara Gianella Weibel talks with Jeff Taylor, community activist and long-term HIV survivor, about a new end-of-life model to study HIV persistence.

HIV/AIDS Last Gift Study: End-of-Life HIV Research

Last Gift Study: End-of-Life HIV Research

Dr Sara Gianella Weibel talks with Dr Davey Smith, head of the Division of Infectious Disease at the University of California, San Diego, about a proposed new model to study HIV persistence, called the Last Gift study.

Clostridium Difficile C difficile Treatment and Prevention: Novel Antibiotics and Immunologic Therapies

C difficile Treatment and Prevention: Novel Antibiotics and Immunologic Therapies

Experts review novel antibiotic therapies that may limit the impact on the gut microbiome, as well as passive immunization products that may bolster the immune response to C difficile toxins and possibly reduce the frequency of toxigenic strains.

Hepatitis Hepatitis C Virus Infection: A Risk Factor for Type 2 Diabetes?

Hepatitis C Virus Infection: A Risk Factor for Type 2 Diabetes?

Hepatitis C virus infection may increase the risk for type 2 diabetes, but whether a causal relationship exists is unclear. Screening for type 2 diabetes in this population may have important public health implications.

Practice Management Addressing Challenges of Medical Liability Reform

Addressing Challenges of Medical Liability Reform

Medical liability remains a troubling issue today, placing a burden on patients and a financial burden of medical practitioners and insurance providers.

Pneumonia Efficacy of Antibiotics for Community-Acquired Pneumonia Evaluated

Efficacy of Antibiotics for Community-Acquired Pneumonia Evaluated

Study finds that over one-fifth of those prescribed an antibiotic for community-acquired pneumonia experience treatment failure.

HIV/AIDS A Transgender Woman's Perspective on HIV Research, Prevention, and Care

A Transgender Woman's Perspective on HIV Research, Prevention, and Care

Dr Sara Gianella talks with Brooke Sullivan, a transgender woman and HIV activist, about ways to improve transgender individuals' involvement in HIV research.

HIV/AIDS PrEP in the Transgender Population: New Study to Examine Effects

PrEP in the Transgender Population: New Study to Examine Effects

Dr Sara Gianella talks with Dr Sheldon Morris, from the University of California San Diego AntiViral Research Center about an upcoming PrEP study in transgender people, including understanding HIV prevention in this population, uptake of PrEP, and adherence to treatment.

Regulatory Issues Congressional Acts Pose Threat to National ID Health Initiatives

Congressional Acts Pose Threat to National ID Health Initiatives

Passage of the 2017 budget, along with congressional approval of the AHCA, leaves large holes in the funding of the proposed national approach to infectious disease control.

Hygiene Periodontal Disease and Rheumatoid Arthritis: What Are the Links?

Periodontal Disease and Rheumatoid Arthritis: What Are the Links?

Bi-directional mechanisms linking periodontal disease to the development of rheumatoid arthritis may offer biomarkers for the development of RA and treatment objectives that influence the courses of both inflammatory conditions.

HIV/AIDS HIV Transmission Through Breastfeeding: New Review and Expert Interview

HIV Transmission Through Breastfeeding: New Review and Expert Interview

Mother-to-child HIV transmission rates are low in the presence of antiretroviral therapy but increase once ART stops at 6 months postpartum.

Practice Management Medical Curbside Consultations: What Are the Legal Risks?

Medical Curbside Consultations: What Are the Legal Risks?

Elisabeth Aron, MD, MPH, takes a look at the legal risks of providing medical curbside consultations.

MRSA Telavancin Efficacy Against Difficult-to-Treat Pathogens

Telavancin Efficacy Against Difficult-to-Treat Pathogens

Theravance Biopharma announced positive results from 3 studies on Vibativ (telavancin), a lipoglycopeptide antibiotic.

Pediatric Illnesses Pertussis Booster Dose Safe in Pediatric Patients With IBD

Pertussis Booster Dose Safe in Pediatric Patients With IBD

A booster dose of pertussis vaccine is safe and immunogenic for pediatric patients with inflammatory bowel disease.

Practice Management Reporting Negative Clinical Trial Results Integral to Research

Reporting Negative Clinical Trial Results Integral to Research

WHO, NIH, and FDA call for the negative or inconclusive results of clinical studies to be published or made publicly available.

Practice Management Improving Care for Medicaid Consumers Under the Affordable Care Act

Improving Care for Medicaid Consumers Under the Affordable Care Act

Despite the increase in coverage under the ACA, data suggest Medicaid patients often had increased wait times for appointments to see healthcare providers.

E. coli Tetravalent E coli Vaccine Safe, Immunogenic in Women With Recurrent UTI

Tetravalent E coli Vaccine Safe, Immunogenic in Women With Recurrent UTI

Phase 1b trial finds tetravalent E coli bioconjugate vaccine candidate in women with recurrent UTI safe and immunogenic.

Practice Management Medical Device Safety: More Active Surveillance Needed

Medical Device Safety: More Active Surveillance Needed

The development of new device technologies points to the need for new strategies to monitor their continuing safety and efficacy.

Clostridium Difficile Review of Clostridium difficile Vaccines in Development

Review of Clostridium difficile Vaccines in Development

Drs Kociolek and Shulman, from the division of infectious diseases at the Ann & Robert H. Lurie Children's Hospital of Chicago in Illinois, review all the current vaccine candidates in development for Clostridium difficile infection.

HIV/AIDS Cardiovascular Disease in Persons With HIV Infection

Cardiovascular Disease in Persons With HIV Infection

Persons living with HIV infection have a higher risk for cardiovascular disease; use of some antiretroviral agents can exacerbate this risk.

Practice Management Improving Resident Handoffs to Enhance Inpatient Care

Improving Resident Handoffs to Enhance Inpatient Care

Recent research found that end-of-rotation transition in care was linked to significantly higher in-hospital mortality.

Practice Management Opposition Voiced Against Republican-led Healthcare Reform

Opposition Voiced Against Republican-led Healthcare Reform

The AMA and ACP voice their opposition after House leadership proposes a new health care act in replacement of Obamacare.

Practice Management FDA Issues Guidance on Medical Product Marketing Language

FDA Issues Guidance on Medical Product Marketing Language

The FDA has released draft guidance documents for appropriate marketing communication on medical products and devices.

Practice Management The Role of Industry Funding on Patient Advocacy Groups

The Role of Industry Funding on Patient Advocacy Groups

An expert Q&A with Susannah L. Rose, PhD, on the prevalence of industry funding of advocacy groups and what clinicians should consider when interpreting research outcomes.

HIV/AIDS Should the FDA Lift the Ban on Blood Donations From MSM?

Should the FDA Lift the Ban on Blood Donations From MSM?

Critics of the FDA's current restriction on blood donation from MSM argue that it is unnecessary and discriminatory, and propose a policy based on individual risk rather than sexual orientation.

HIV/AIDS HIV Research in Women: Expert Q&A

HIV Research in Women: Expert Q&A

Drs Gianella and Karris discuss the many factors that play a role in the underrepresentation of women in HIV research.

Practice Management How Does Student Well-Being Affect Medical Education?

How Does Student Well-Being Affect Medical Education?

Medical students learn better when they are in a good state of mind, researchers found.

Antibiotics, Antimicrobial Resistance Clinicians Reduce Antibiotic Overuse Using Simulation Tool

Clinicians Reduce Antibiotic Overuse Using Simulation Tool

A virtual simulation allows clinicians to role play to improve clinician-patient communication.

HIV/AIDS Confronting Coronary Heart Disease in HIV/AIDS

Confronting Coronary Heart Disease in HIV/AIDS

A review of coronary heart disease in patients with HIV.

Practice Management Cleveland Clinic Shares Top 2017 Medical Innovations

Cleveland Clinic Shares Top 2017 Medical Innovations

More than 100 clinicians and researchers identified the top 10 most anticipated medical innovations of 2017.

Practice Management US Election: What's in Store for the Affordable Care Act?

US Election: What's in Store for the Affordable Care Act?

Speculation surrounds the new administration's plan for the Affordable Care Act (ACA).

Practice Management Steps for Improving Medical Education Considered

Steps for Improving Medical Education Considered

Researchers and physicians explore what's working and not working in medical education.

Practice Management The Future of Artificial Intelligence in Clinical Care

The Future of Artificial Intelligence in Clinical Care

Although there are delays in implementation, artificial intelligence has many potential applications in medicine.

Practice Management Benefits and Barriers Associated With Patient EHR Access

Benefits and Barriers Associated With Patient EHR Access

The increase in direct patient access to online health records confers multiple benefits, though disparities in access should be addressed.

HIV/AIDS HIV Care Continuum: Improving Future Outcomes

HIV Care Continuum: Improving Future Outcomes

While 86% of all persons living with HIV in the US know that they are HIV-infected, only an estimated 35% actually achieve viral suppression.

Hygiene Hand Washing Compliance Rates in Early Childhood Care Centers

Hand Washing Compliance Rates in Early Childhood Care Centers

Hand washing compliance was less than 30% among caregivers working with children between infancy and 5-years-old.

Waterborne Illnesses FDA Approves Vaxchora for Cholera

FDA Approves Vaxchora for Cholera

The CDC's Advisory Committee on Immunization Practices voted unanimously to recommend Vaxchora for US travelers to areas of active cholera transmission.

Antibiotics, Antimicrobial Resistance Influence of Electronics on Antibiotic Prescription Rates Appears Limited

Influence of Electronics on Antibiotic Prescription Rates Appears Limited

Although certain behavioral interventions did not work, methods are needed to reduce antibiotic overuse.

Practice Management Coding Practices Might Explain Lower Pay in Women Doctors

Coding Practices Might Explain Lower Pay in Women Doctors

The reimbursement gap between male and female doctors might be due to coding practices and accuracy.

Antibiotics, Antimicrobial Resistance Patterns of Antibiotic Resistant mcr-1 Gene Suggest Low Transmission Risk

Patterns of Antibiotic Resistant mcr-1 Gene Suggest Low Transmission Risk

Person-to-person or environmental transmission is low in mcr-1 gene antibiotic resistant bacteria.

HIV/AIDS Efforts to Boost HIV Testing Rates Working, But Work Remains

Efforts to Boost HIV Testing Rates Working, But Work Remains

Ramped up efforts to encourage more men who have sex with men to get tested for HIV have made an impact, but rates are still lower than needed.

Hepatitis Reports Provide Guidance on HBV Testing, Address Challenges for HBV Response

Reports Provide Guidance on HBV Testing, Address Challenges for HBV Response

Two reports call attention to importance of diagnosing, treating HBV.

Practice Management Addressing EMR Interoperability, Productivity, and Lack of Specificity

Addressing EMR Interoperability, Productivity, and Lack of Specificity

Many providers still find EMRs vexing, even after all these years.

Clostridium Difficile Prevention and Treatment of C Difficile

Prevention and Treatment of C Difficile

New treatment strategies are necessary as researchers work to prevent C difficile infection.

Sexually Transmitted Diseases Growing Antibiotic Resistance Prompts Updated STI Guidelines

Growing Antibiotic Resistance Prompts Updated STI Guidelines

WHO releases new treatment guidelines for chlamydia, gonorrhea, and syphilis

Influenza How Does Statin Use Impact Flu Vaccine Efficacy?

How Does Statin Use Impact Flu Vaccine Efficacy?

The researchers noted that earlier studies had shown that statins have proven anti-inflammatory effects, and older adults who usually take these medications are also more at risk for complications from influenza.

Emerging Diseases Climate Change Will Likely Challenge Current Malaria Control Programs

Climate Change Will Likely Challenge Current Malaria Control Programs

Sustained control efforts are necessary, 'as the effects of the flood on malaria transmission may continue for up to one year after the initial event.'

HIV/AIDS IDSA Guidelines Urge 'Prompt Coordinated Treatment' for HIV and TB

IDSA Guidelines Urge 'Prompt Coordinated Treatment' for HIV and TB

The guidelines note that TB treatment should begin as soon as the patient is suspected of having active TB disease, even before test results confirm the diagnosis.

MRSA Staphylococcus aureus Nasal Colonization Associated With SLE Disease Phenotype

Staphylococcus aureus Nasal Colonization Associated With SLE Disease Phenotype

S aureus colonization was associated with particular SLE phenotypes.

Pneumonia IDSA: Shorter Courses of Antibiotics Safe for Treating HAP, VAP

IDSA: Shorter Courses of Antibiotics Safe for Treating HAP, VAP

Published in 2005, the previous guidelines recommended different lengths of treatment time for antibiotic therapy based on the bacterium causing the infection.

Treatments Updated IDSA Guidelines on Valley Fever: Early Diagnosis Key to Treatment

Updated IDSA Guidelines on Valley Fever: Early Diagnosis Key to Treatment

The updated guidelines note that coccidioidomycosis, originally nicknamed San Joaquin Valley fever, may be overlooked as a cause of illness, which may lead to unnecessary blood imaging tests and antibiotic use.

Hepatitis IDSA, AASLD Update Hepatitis Guidance

IDSA, AASLD Update Hepatitis Guidance

The update also offers guidance regarding the prudent use of HCV resistance testing, a source of considerable confusion for practitioners.

Sexually Transmitted Diseases Gonorrhea Treatment Options Threatened as Resistance Emerges

Gonorrhea Treatment Options Threatened as Resistance Emerges

Signs of emerging resistance to azithromycin suggests that this drug will be next in the long line of antibiotics to which gonorrhea bacteria have become resistant - a list that includes penicillin, tetracycline, and fluoroquinolones.

Ebola What Role Did the CDC Play in the Ebola Response?

What Role Did the CDC Play in the Ebola Response?

CDC activated its Emergency Operations Center (EOC) for the Ebola response on July 9, 2014.

Emerging Diseases New Research Notes Natural Compounds Effective Against Pathogens Causing Lyme Disease

New Research Notes Natural Compounds Effective Against Pathogens Causing Lyme Disease

The study revealed that polyphenols such as baicalein, luteolin, and rosmarinic acid, fatty acids namely monolaurin and 10-HAD, and micronutrients like iodine and vitamins D3 and C were particularly effective.

E. coli Higher Bacterial Loads Resulted in Greater Hand-to-Hand Transmission

Higher Bacterial Loads Resulted in Greater Hand-to-Hand Transmission

One important issue derived from the study is that it sets a target that may be useful for the norms evaluating hand hygiene products, and also for future studies comparing different hand hygiene products.

ASM 2016 ASM 2016: Hospitals Not At Top of List to Blame in Clostridium Difficile Transmission

ASM 2016: Hospitals Not At Top of List to Blame in Clostridium Difficile Transmission

Importance of C difficile transmission routes varies by setting.

Hygiene Contaminated Gloves Boosts Risks of Cross-transmission of Pathogens

Contaminated Gloves Boosts Risks of Cross-transmission of Pathogens

Failure to change or remove contaminated gloves carries a high-risk of healthcare-associated pathogens transmission.

Antibiotics, Antimicrobial Resistance Post-operative Antibiotic Prophylaxis Did Not Reduce Surgical Site Infections

Post-operative Antibiotic Prophylaxis Did Not Reduce Surgical Site Infections

Numerous studies have shown no benefit in continuing antibiotics after surgery.

Respiratory Addressing Altered Vaccine Immunogenicity and Low Vaccination Rates in Those With Autoimmune Diseases

Addressing Altered Vaccine Immunogenicity and Low Vaccination Rates in Those With Autoimmune Diseases

Despite decades of research on the disproportionate impact of infection on those with rheumatic disease, patients in this population are less likely than those without rheumatic disease to undergo routine vaccination.

Chlamydia APIC: Many ED Patients Suspected to Have Chlamydia, Gonorrhea Receive Unnecessary Antibiotics

APIC: Many ED Patients Suspected to Have Chlamydia, Gonorrhea Receive Unnecessary Antibiotics

Of the 1,103 patients tested, 40% were treated with antibiotics for gonorrhea and/or chlamydia; of those treated, 76.6% ultimately tested negative for having the STD.

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