The development of new device technologies points to the need for new strategies to monitor their continuing safety and efficacy.
Drs Kociolek and Shulman, from the division of infectious diseases at the Ann & Robert H. Lurie Children's Hospital of Chicago in Illinois, review all the current vaccine candidates in development for Clostridium difficile infection.
Persons living with HIV infection have a higher risk for cardiovascular disease; use of some antiretroviral agents can exacerbate this risk.
Recent research found that end-of-rotation transition in care was linked to significantly higher in-hospital mortality.
The AMA and ACP voice their opposition after House leadership proposes a new health care act in replacement of Obamacare.
Intravenous zanamivir is as safe and efficacious as oral oseltamivir in hospitalized patients with severe influenza.
Intravenous daptomycin may be effective and well-tolerated in children, possibly providing an alternative treatment against methicillin-resistant Staphylococcus aureus (MRSA) skin infections in this patient population.
The FDA has released draft guidance documents for appropriate marketing communication on medical products and devices.
An expert Q&A with Susannah L. Rose, PhD, on the prevalence of industry funding of advocacy groups and what clinicians should consider when interpreting research outcomes.
Critics of the FDA's current restriction on blood donation from MSM argue that it is unnecessary and discriminatory, and propose a policy based on individual risk rather than sexual orientation.
Study finds that patients were 10% to 30% less likely to acquire a multidrug-resistant organism or C difficile if enhanced disinfection strategies were used in hospitals.
Contrary to previous studies, this study found an increased hospitalization risk for community-acquired pneumonia with higher-potency vs lower-potency statins.
Drs Gianella and Karris discuss the many factors that play a role in the underrepresentation of women in HIV research.
Medical students learn better when they are in a good state of mind, researchers found.
A virtual simulation allows clinicians to role play to improve clinician-patient communication.
A review of coronary heart disease in patients with HIV.
More than 100 clinicians and researchers identified the top 10 most anticipated medical innovations of 2017.
A new vaccine for Ebola showed high efficacy in preventing the development of Ebola in clusters of people exposed to the virus, and protection was also conferred to those who were not vaccinated.
Speculation surrounds the new administration's plan for the Affordable Care Act (ACA).
Researchers and physicians explore what's working and not working in medical education.
Although there are delays in implementation, artificial intelligence has many potential applications in medicine.
The increase in direct patient access to online health records confers multiple benefits, though disparities in access should be addressed.
Models predicted dengue vaccine would reduce rates of hospitalization in high-transmission areas but increase rates in lower-transmission areas.
High-dose vitamin D supplementation reduced the incident of acute respiratory infection in older long-term care residents.
While 86% of all persons living with HIV in the US know that they are HIV-infected, only an estimated 35% actually achieve viral suppression.
Although certain behavioral interventions did not work, methods are needed to reduce antibiotic overuse.
New guidelines call for doxycycline, ceftriaxone, or azithromycin when benzathine or procaine penicillin aren't available.
Researchers found only 3 cases of follicular trachoma and one case of infection in 2 districts, well below the World Health Organization criteria.
Household transmission of C difficile infection could be responsible for a bacterial reservoir for community-associated cases.
The use of prophages can reduce invasiveness in S aureus infections of diabetic foot ulcers that limit intracellular growth.
Nosocomial legionellosis as a result of heat exchangers installed in a hospital in Sherbrooke, Canada.
The reimbursement gap between male and female doctors might be due to coding practices and accuracy.
Clinicians discussed their perspectives from the research during the 1976 outbreak.
Person-to-person or environmental transmission is low in mcr-1 gene antibiotic resistant bacteria.
Ramped up efforts to encourage more men who have sex with men to get tested for HIV have made an impact, but rates are still lower than needed.
Transmission risk of a urinary tract infection caused by drug resistant, mcr-1-positive Escherichia coli seems to be low.
Two reports call attention to importance of diagnosing, treating HBV.
Antibiotic resistance to Salmonella is a serious concern for public health and clinical providers.
Many providers still find EMRs vexing, even after all these years.
New treatment strategies are necessary as researchers work to prevent C difficile infection.
WHO releases new treatment guidelines for chlamydia, gonorrhea, and syphilis
The researchers noted that earlier studies had shown that statins have proven anti-inflammatory effects, and older adults who usually take these medications are also more at risk for complications from influenza.
Sustained control efforts are necessary, 'as the effects of the flood on malaria transmission may continue for up to one year after the initial event.'
The guidelines note that TB treatment should begin as soon as the patient is suspected of having active TB disease, even before test results confirm the diagnosis.
S aureus colonization was associated with particular SLE phenotypes.
Published in 2005, the previous guidelines recommended different lengths of treatment time for antibiotic therapy based on the bacterium causing the infection.
The updated guidelines note that coccidioidomycosis, originally nicknamed San Joaquin Valley fever, may be overlooked as a cause of illness, which may lead to unnecessary blood imaging tests and antibiotic use.
The update also offers guidance regarding the prudent use of HCV resistance testing, a source of considerable confusion for practitioners.
Signs of emerging resistance to azithromycin suggests that this drug will be next in the long line of antibiotics to which gonorrhea bacteria have become resistant - a list that includes penicillin, tetracycline, and fluoroquinolones.
CDC activated its Emergency Operations Center (EOC) for the Ebola response on July 9, 2014.
The study revealed that polyphenols such as baicalein, luteolin, and rosmarinic acid, fatty acids namely monolaurin and 10-HAD, and micronutrients like iodine and vitamins D3 and C were particularly effective.
One important issue derived from the study is that it sets a target that may be useful for the norms evaluating hand hygiene products, and also for future studies comparing different hand hygiene products.
Importance of C difficile transmission routes varies by setting.
Failure to change or remove contaminated gloves carries a high-risk of healthcare-associated pathogens transmission.
Numerous studies have shown no benefit in continuing antibiotics after surgery.
Addressing Altered Vaccine Immunogenicity and Low Vaccination Rates in Those With Autoimmune Diseases
Despite decades of research on the disproportionate impact of infection on those with rheumatic disease, patients in this population are less likely than those without rheumatic disease to undergo routine vaccination.
Of the 1,103 patients tested, 40% were treated with antibiotics for gonorrhea and/or chlamydia; of those treated, 76.6% ultimately tested negative for having the STD.
About 22% of 6232 patients did not complete latent tuberculosis (LTBI) treatment.
Problems identified in these building-associated outbreaks included inadequate disinfectant levels, human error, and equipment breakdowns
Following the year-long study period, the intervention group had a testing rate of 63.7% and the comparison group had 42%.
Evidence may suggest that universal test of cure may not be necessary for all patients.
Researchers found the multidrug resistant bacteria in a woman who sought treatment for UTI.
While Chlamydia trachomatis is the most reported genitourinary pathogen causing ReA, other bacteria including E. coli and Enterococcus faecalis have been implicated in the pathogenesis of ReA.
Thanks in large part to antiretroviral therapy, patients with HIV are living longer, but they and the physicians who treat them are facing unique challenges as they age.
Healthy and Safe Swimming Week begins on May 23, 2016.
Patients and providers have different perceptions, behaviors, and knowledge on antibiotic usage.
College-aged students may benefit from continued education regarding the spread of HPV, especially oral transmission.
Emory researchers have made new data analyses of where gay and bisexual men are most likely to be infected with HIV. The data will be used to direct vital HIV resources to areas of the most need.
A second CDC study, published online this month in Clinical Infectious Diseases, shows that annual hepatitis C-related mortality in 2013 surpassed the total combined number of deaths from 60 other infectious diseases reported to CDC.
Challenges of managing inflammatory arthritis in patients infected with HIV include difficulties in assessing disease activity and limited safety information for the use of immunosuppresive drugs in this patient population.
Patients depend on their medical team to help them get well, and the first step is making sure healthcare professionals aren't exposing them to new infections.
Foodnet officials attribute the increases to the wider use of culture-independent diagnostic tests (CIDTs).
WHO issued its first-ever recommendations on the treatment of hepatitis C virus (HCV) two years ago, but since then, several new medicines, specifically direct-acting antivirals (DAAs), have been approved.
The six-step technique was determined to be microbiologically more effective for reducing the median bacterial count (3.28 to 2.58) compared to the three-step method.
Cancer prevention efforts for patients with HIV should focus on smoking cessation and appropriate screening based on recommendations for the general population.
Guidelines for patients with coinfection sorely needed.
The date indicated nucleic amplification tests were sensitive and specific for CDI when cultures were used as the reference standard.
Nevirapine-based ART did not have a negative impact on levonorgestrel exposure or efficacy.
Coding artifact may be contributing to the apparent rise in sepsis incidence and decline in mortality.
Patients with COP generally have positive outcomes following a definitive diagnosis and the initiation of appropriate treatment.
The 83 labs in the national PulseNet network enter information into a database accessible to local and state health officials.
There are high cumulative incidences of...Kaposi sarcoma, non-Hodgkin lymphoma, and lung cancer" in patients with HIV when compared with those who did not have HIV.
The systematic literature review identified risk factors and protective factors that affect adolescents with chronic conditions.
Education of high risk populations and regular testing are crucial steps clinicians can take to stem the spread of hepatitis C infection.
Should the focus shift to how best to reach men in trials?
The use of biologic agents in treatment of patients rheumatoid arthritis or psoriasis is associated with a significant risk of heptatis B flares.
By presenting research on the safety and efficacy of the flu vaccine, clinicians can successfully promote vaccination to patients in their care.
Study findings also prompted Dr Sissoko and his team to recommend instituting semen testing and dedicated counseling in long-term care programs, and encouraging condom use to reduce the risk for sexual transmission.
Researchers will present data from nearly 1,000 studies exploring the epidemiology and biology of human retroviruses and associated diseases
The researchers identified three types of delirium and other brain problems related to antibiotics.
Each year, about 500 to 600 HIV-positive, would-be organ donors had organs that could have saved people if only the medical community was allowed to use the organs for transplant.
Lower 30-day mortality for AMI, heart failure, but not pneumonia, with admission to VA hospitals.
The Tdap vaccine for adolescents provides moderate protection for 1 year after vaccination, after which efficacy declines.
Children with recurrent acute or chronic pancreatitis are likely to have high healthcare costs and a high risk for repeat hospitalization.
While some signs have emerged that the HIV epidemic is loosening its grip on the black community, persistent disparities are prolonging the epidemic.
Interim guidelines developed for evaluation of infants with possible congenital Zika virus infection.
Other studies have shown that estrogens have antiviral properties against HIV, Ebola and hepatitis viruses.
The purpose of this contest is to identify innovative examples of delivering hepatitis B and C testing that will be highlighted within the 2016 WHO Hepatitis Testing Guidelines.
Sign Up for Free e-newsletters
Infectious Disease Advisor Articles
- Review of Clostridium difficile Vaccines in Development
- The Handoff: Your Week in Infectious Disease News - 3/24/17
- Diagnosing Pneumonia: Ultrasound More Accurate Than Radiology
- Antibiotic Prescribing Habits Vary Widely Across Practices in Children With CAP
- High Cardiac Troponin Levels Predict Mortality in CAP
- Clinical Guideline on Evaluating Abnormal Liver Chemistries
- FDA Approves Procalcitonin Biomarker Test to Aid Antibiotic Decision Making
- Review of Clostridium difficile Vaccines in Development
- WHO Prioritizes Antibiotic-Resistant Bacteria on Pathogens List
- Abnormal Bone Metabolism With Tenofovir for HBV Infection
- Tetravalent E coli Vaccine Safe, Immunogenic in Women With Recurrent UTI
- Gastric Acid Suppression Linked With Increased Risk of Recurrent CDI
- Optimizing HPV Vaccination Rates With Education
- No Benefit of Prophylactic Platelet Transfusion for Bleeding Prevention in Dengue
- Medical Device Safety: More Active Surveillance Needed