H pylori Recurrence Low One Year After Eradication
Risk factors for recurrence were peptic ulcer, contact with infected people, and hospitalization.
HealthDay News — The recurrence of Helicobacter pylori infection one year after eradication is low, according to a study published in the Journal of Digestive Diseases.
Li Ya Zhou, from the Peking University Third Hospital in Beijing, and colleagues assessed the recurrence rate of H pylori infection among 827 patients receiving successful H pylori eradication in a previous randomized controlled trial. A 13C-urea breath test was administered one year after eradication therapy.
The researchers found that based on an 89.8% follow-up rate (743 patients), the annual recurrence rate of H pylori infection was 1.75% (13 patients). Questionnaires completed by 692 patients (13 recurrence and 679 non-recurrence) showed that peptic ulcer disease (odds ratio [OR], 3.385), contact with other individuals with H pylori infection (OR, 4.231), and hospitalization (OR, 9.302) were independent risk factors for H pylori infection recurrence.
"The recurrence of H pylori infection one year after eradication is low in urban population of China," the authors write.
Zhou LY, Song ZQ, Xue Y, Li X, Li YQ, Qian JM. Recurrence of Helicobacter pylori infection and the affecting factors: a follow-up study [published online December 27, 2016]. J Dig Dis. doi: 10.1111/1751-2980.12440