GI Illness

Should Metronidazole Be Recommended for Mild Clostridium difficile Infections?

Should Metronidazole Be Recommended for Mild Clostridium difficile Infections?

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Clinicians debate whether metronidazole should be used as front-line treatment for mild CDI in patients with low risk for complications.

70 Sickened So Far in Salmonella-Tainted Melon Outbreak

70 Sickened So Far in Salmonella-Tainted Melon Outbreak

Illnesses reported in Illinois, Indiana, Kentucky, Michigan, Missouri, Ohio, and Tennessee

Novel Antibiotic for <i>C Difficile</i> Infection Gets FDA's QIDP Designation

Novel Antibiotic for C Difficile Infection Gets FDA's QIDP Designation

ACX-362E is a targeted, narrow spectrum oral antibiotic that blocks the DNA replication process through inhibition of polymerase III, which has been shown to be bactericidal.

Kellogg's Honey Smacks Cereal Recalled Due to <i>Salmonella</i> Risk

Kellogg's Honey Smacks Cereal Recalled Due to Salmonella Risk

The Kellogg Company has announced it is recalling certain boxes of Honey Smacks cereal due to the possibility of contamination with Salmonella

No Association Between Rotavirus Vaccination and Intussusception in New Study

No Association Between Rotavirus Vaccination and Intussusception in New Study

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The risk of intussusception within 1 to 7 days and 8 to 21 days after rotavirus vaccination was assessed in infants age 28 to 245 days.

60 Sickened So Far in Salmonella-Tainted Melon Outbreak

60 Sickened So Far in Salmonella-Tainted Melon Outbreak

31 people have been hospitalized; no deaths reported to date

CDC Says <i> E Coli </i> Outbreak Tied to Romaine Lettuce Is Over

CDC Says E Coli Outbreak Tied to Romaine Lettuce Is Over

CDC reports this spring's outbreak of Escherichia coli illness tied to tainted Arizona romaine lettuce is likely over.

<i>C difficile</i> Risk Higher With Stoma Reversal vs Colectomy

C difficile Risk Higher With Stoma Reversal vs Colectomy

Given the impact of postoperative Clostridium difficile infection, a heightened sense of suspicion should be given to symptomatic patients after stoma reversal.

<i>Clostridium difficile</i> Infection in the Intensive Care Setting

Clostridium difficile Infection in the Intensive Care Setting

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It is important to understand the relative severity of CDI in patients in the ICU because it effects treatment decisions. However, primary prevention remains a vitally important strategy to limit morbidity and mortality related to CDI in this vulnerable patient population.

FDA Issues Mandatory Recall for Food Products Containing Powdered Kratom

FDA Issues Mandatory Recall for Food Products Containing Powdered Kratom

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The agency took this action after Triangle Pharmanaturals LLC failed to cooperate with the FDA's request to conduct a voluntary recall.

1980 to 2014 Saw Decrease in US Mortality From Infectious Diseases

1980 to 2014 Saw Decrease in US Mortality From Infectious Diseases

There were declines in mortality from most categories of infectious diseases, with large differences among US counties. However, over this time there was an increase in mortality for diarrheal diseases.

Firvanq Availability Replaces Need for Compounded Oral Vancomycin Solution

Firvanq Availability Replaces Need for Compounded Oral Vancomycin Solution

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FIRVANQ is commercially available in 25 and 50 mg/mL strengths in convenient 150 mL and 300 mL sizes.

<i>H pylori</i> Treatment Tied to Lower Metachronous Gastric Cancer Risk

H pylori Treatment Tied to Lower Metachronous Gastric Cancer Risk

Helicobacter pylori treatment is associated with a reduced rate of metachronous gastric cancer.

Recurrent Salmonella enterica Typhimurium infection disables host protection against intestinal inflammation [PreClinical]

Increased turnover of intestinal alkaline phosphatase (IAP), related to increased endogenous neuraminidase activity among duodenal enterocytes, was found to be associated with inflammatory bowel disease.

FDA: Vancomycin Liquid Oral Treatment Approved for <i>C diff</i>-Associated Diarrhea

FDA: Vancomycin Liquid Oral Treatment Approved for C diff-Associated Diarrhea

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Vancomycin is the first liquid oral treatment for C diff-associated diarrhea.

<i>Helicobacter pylori</i> Infection Linked to Gallbladder Diseases

Helicobacter pylori Infection Linked to Gallbladder Diseases

Study aimed to clarify the prevalence of gallbladder diseases, and factors related to gallbladder diseases, and relationships between H pylori infection, gallstones, cholecystitis, and cholecystic polypus.

Delaying Rotavirus Vaccination Until Discharge Leads to Missed Opportunities

Delaying Rotavirus Vaccination Until Discharge Leads to Missed Opportunities

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Study found that many hospitalized infants did not receive rotavirus vaccination before discharge and were no longer age-eligible for vaccination after discharge from the hospital.

Raw Flour Linked to <i>Escherichia coli</i>

Raw Flour Linked to Escherichia coli

Raw flour has been linked to E coli infections in 24 states.

IDSA Updates Infectious Diarrhea Guidelines

IDSA Updates Infectious Diarrhea Guidelines

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The Infectious Diseases Society of America updated its guidelines for the management of acute or persistent infectious diarrhea.

Efficacy of <i>Goshuyuto</i>/Rabeprazole for Refractory <i>H pylori</i>

Efficacy of Goshuyuto/Rabeprazole for Refractory H pylori

Refractory Helicobacter pylori infection can be successfully treated with goshuyuto and rabeprazole.

Better Detection and Treatment Needed for <i>H pylori</i> Infections in Children

Better Detection and Treatment Needed for H pylori Infections in Children

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In recent years, a link between childhood Helicobacter pylori and gastric cancer in adulthood has elevated the need to detect and treat H pylori in asymptomatic children.

Bezlotoxumab Reduces 30-Day Hospital Readmissions for <I>C difficile</I> Infection

Bezlotoxumab Reduces 30-Day Hospital Readmissions for C difficile Infection

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Bezlotoxumab, given with antibacterials for Clostridium difficile, could be effective as a preventive treatment for C difficile infection.

Rotavirus Vaccine Linked to Decrease In Pediatric Gastroenteritis Hospitalizations

Rotavirus Vaccine Linked to Decrease In Pediatric Gastroenteritis Hospitalizations

Implementation of rotavirus vaccination correlated with a reduction in acute gastroenteritis related hospitalization rates among children.

CDC Issues Advisory on the Rise of Cyclosporiasis

CDC Issues Advisory on the Rise of Cyclosporiasis

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The CDC Health Alert Network has issued an advisory regarding an increase in cases of the intestinal illness cyclosporiasis.

Biotherapeutics for the Prevention of <i>Clostridium difficile</i> Infection

Biotherapeutics for the Prevention of Clostridium difficile Infection

Experts review biotherapeutics for the prevention of C difficile infection, including probiotics, fecal microbiota transplantation, and nontoxigenic C difficile.

Efficacy of Bismuth-Based Quad Tx vs Levofloxacin Triple Tx for <i>H pylori</i>

Efficacy of Bismuth-Based Quad Tx vs Levofloxacin Triple Tx for H pylori

The addition of bismuth subcitrate to levofloxacin-based triple therapy is not associated with increased effectiveness in patients with Helicobacter pylori infection.

Multiply Recurrent <I>C difficile</I> Infection Rate 4 Times Higher Than CDI

Multiply Recurrent C difficile Infection Rate 4 Times Higher Than CDI

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The rate of multiply recurrent Clostridium difficile (mrCDI) was found to be more than 4 times higher than that of original CDI, with important implications for treatment decisions.

<I>Clostridium difficile</i> Infection Rates Increase in Patients With Cancer

Clostridium difficile Infection Rates Increase in Patients With Cancer

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Results of a recent study have shown that infection with Clostridium difficile is increasing in frequency and negatively affects clinical and care outcomes in patients with cancer.

New Method Gauges Persistence of Donor Microbes After Fecal Transplant

New Method Gauges Persistence of Donor Microbes After Fecal Transplant

Therapeutic donor microbes can remain for months or years in patients who've undergone fecal microbiota transplantation.

Liver Cancer Mortality Rates Have Doubled Since Mid-1980s

Liver Cancer Mortality Rates Have Doubled Since Mid-1980s

Liver cancer has become the fastest growing cause of cancer deaths in the Unites States.

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