GI Illness

Bezlotoxumab Reduces 30-Day Hospital Readmissions for <I>C difficile</I> Infection

Bezlotoxumab Reduces 30-Day Hospital Readmissions for C difficile Infection

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Bezlotoxumab, given with antibacterials for Clostridium difficile, could be effective as a preventive treatment for C difficile infection.

Rotavirus Vaccine Linked to Decrease In Pediatric Gastroenteritis Hospitalizations

Rotavirus Vaccine Linked to Decrease In Pediatric Gastroenteritis Hospitalizations

Implementation of rotavirus vaccination correlated with a reduction in acute gastroenteritis related hospitalization rates among children.

CDC Issues Advisory on the Rise of Cyclosporiasis

CDC Issues Advisory on the Rise of Cyclosporiasis

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The CDC Health Alert Network has issued an advisory regarding an increase in cases of the intestinal illness cyclosporiasis.

Biotherapeutics for the Prevention of <i>Clostridium difficile</i> Infection

Biotherapeutics for the Prevention of Clostridium difficile Infection

Experts review biotherapeutics for the prevention of C difficile infection, including probiotics, fecal microbiota transplantation, and nontoxigenic C difficile.

Efficacy of Bismuth-Based Quad Tx vs Levofloxacin Triple Tx for <i>H pylori</i>

Efficacy of Bismuth-Based Quad Tx vs Levofloxacin Triple Tx for H pylori

The addition of bismuth subcitrate to levofloxacin-based triple therapy is not associated with increased effectiveness in patients with Helicobacter pylori infection.

Multiply Recurrent <I>C difficile</I> Infection Rate 4 Times Higher Than CDI

Multiply Recurrent C difficile Infection Rate 4 Times Higher Than CDI

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The rate of multiply recurrent Clostridium difficile (mrCDI) was found to be more than 4 times higher than that of original CDI, with important implications for treatment decisions.

<I>Clostridium difficile</i> Infection Rates Increase in Patients With Cancer

Clostridium difficile Infection Rates Increase in Patients With Cancer

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Results of a recent study have shown that infection with Clostridium difficile is increasing in frequency and negatively affects clinical and care outcomes in patients with cancer.

New Method Gauges Persistence of Donor Microbes After Fecal Transplant

New Method Gauges Persistence of Donor Microbes After Fecal Transplant

Therapeutic donor microbes can remain for months or years in patients who've undergone fecal microbiota transplantation.

Liver Cancer Mortality Rates Have Doubled Since Mid-1980s

Liver Cancer Mortality Rates Have Doubled Since Mid-1980s

Liver cancer has become the fastest growing cause of cancer deaths in the Unites States.

<i>C difficile</i> Treatment and Prevention: Novel Antibiotics and Immunologic Therapies

C difficile Treatment and Prevention: Novel Antibiotics and Immunologic Therapies

Experts review novel antibiotic therapies that may limit the impact on the gut microbiome, as well as passive immunization products that may bolster the immune response to C difficile toxins and possibly reduce the frequency of toxigenic strains.

Case of <i>Vibrio vulnificus</i> Septic Shock Leading to Death After New Tattoo

Case of Vibrio vulnificus Septic Shock Leading to Death After New Tattoo

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A patient who recently acquired a new tattoo developed Vibrio vulnificus septic shock after swimming in seawater, leading to death.

Ridinilazole Beats Standard of Care in Phase 2 <i>C difficile</i> Study

Ridinilazole Beats Standard of Care in Phase 2 C difficile Study

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Recurrent Clostridium difficile infection is associated with a significant economic and mortality burden, but new treatment shows promise.

Oral Prophylactic Therapy Designated Breakthrough Therapy for CDI Prevention

Oral Prophylactic Therapy Designated Breakthrough Therapy for CDI Prevention

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The FDA granted Breakthrough Therapy designation to Synthetic Biologics' ribaxamase SYN-004 for Clostridium difficile infection prevention.

Intestinal Dysbiosis May Link ME/CFS With GI and Neurological Disturbances

Intestinal Dysbiosis May Link ME/CFS With GI and Neurological Disturbances

Findings indicate that dysbiotic features that are uniquely ME/CFS-associated may be masked by disturbances arising from the high prevalence of IBS co-morbidity in ME/CFS.

Community-based Risk Factors for <i>C difficile</i> Infection in Children

Community-based Risk Factors for C difficile Infection in Children

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Community-associated C difficile infection in children was linked to the combination of commonly used antibiotics and exposure to the bacterium in the home and outpatient healthcare settings.

CDC Issues New Recommendations for Treating <i>Shigella</i> Infection

CDC Issues New Recommendations for Treating Shigella Infection

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The CDC has issued an alert regarding new recommendations for the treatment of Shigella infection.

CDC Lists Top Pathogens for Foodborne Illnesses

CDC Lists Top Pathogens for Foodborne Illnesses

Researcher found that while Salmonella infections decreased, reported Yersinia, Cryptosporidium, and Shiga toxin-producing E coli infections increased.

Gastric Acid Suppression Linked With Increased Risk of Recurrent CDI

Gastric Acid Suppression Linked With Increased Risk of Recurrent CDI

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A meta-analysis study shows patients who take gastric acid suppressants have a higher risk for recurrent Clostridium difficile infection.

Review of <i>Clostridium difficile</i> Vaccines in Development

Review of Clostridium difficile Vaccines in Development

Drs Kociolek and Shulman, from the division of infectious diseases at the Ann & Robert H. Lurie Children's Hospital of Chicago in Illinois, review all the current vaccine candidates in development for Clostridium difficile infection.

Clinical Guideline on Evaluating Abnormal Liver Chemistries

Clinical Guideline on Evaluating Abnormal Liver Chemistries

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The American College of Gastroenterology released a set of guideline for evaluating abnormal liver chemistries.

Facilitating Care for Patients With Early Stage Hepatocellular Carcinoma

Facilitating Care for Patients With Early Stage Hepatocellular Carcinoma

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Investigators proposed an algorithm to facilitate the decision-making process of clinical care for patients with very early hepatocellular carcinoma.

Acute Myocardial Infarction Common in Renal Transplant Recipients

Acute Myocardial Infarction Common in Renal Transplant Recipients

Acute STEMI accounted for 29.3% of renal transplant recipients admissions.

High Rate of Metronidazole Resistance Seen in <i>C difficile</i> Infection

High Rate of Metronidazole Resistance Seen in C difficile Infection

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Antibiotic resistance to therapies for Clostridium difficile infection are common, and their patterns should be considered in algorithms designed to select therapies.

Severe CDI Treatment With Vancomycin Has Lower 30-Day Mortality Risk

Severe CDI Treatment With Vancomycin Has Lower 30-Day Mortality Risk

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No difference in the risk of Clostridium difficile infection (CDI) recurrence observed with vancomycin or metronidazole but 30-day mortality risk was significantly lower among patients with severe CDI treated with vancomycin.

Fecal Microbiota Transplant Effective for <i>C difficile</i> in Pregnancy

Fecal Microbiota Transplant Effective for C difficile in Pregnancy

A 28-year-old pregnant woman who presented with recurrent C difficile infection underwent a successful fecal microbiota transplant at 18 weeks of gestation.

Strategies for Increasing Hepatocellular Carcinoma Screening

Strategies for Increasing Hepatocellular Carcinoma Screening

Outreach strategies doubled the percentage of patients with cirrhosis who underwent ultrasound screening for HCC.

Short-Duration Triple DAA for Chronic HCV With Portal Hypertension

Short-Duration Triple DAA for Chronic HCV With Portal Hypertension

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Trial finds the combination of simeprevir, daclatasvir, and sofosbuvir generally safe and well tolerated in HCV patients with decompensated liver disease.

Diet and Exercise Reduces Portal Pressure in Patients With Cirrhosis

Diet and Exercise Reduces Portal Pressure in Patients With Cirrhosis

In overweight/obese patients with cirrhosis and portal hypertension, a 16-weeks of diet and moderate exercise were safe and reduced body weight and portal pressure.

GI Inflammation Linked to Type 1 Diabetes

GI Inflammation Linked to Type 1 Diabetes

Duodenal mucosa in type 1 diabetes present with disease-specific abnormalities and inflammation, according to researchers.

Oral Antibiotics as Effective as Fecal Transplant for <i>C difficile</i>

Oral Antibiotics as Effective as Fecal Transplant for C difficile

Results showed no real difference in outcomes when comparing fecal transplant and antibiotic treatment.

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