Hepatitis C

Two Hepatitis C Virus Infection Treatments to Be Discontinued

Two Hepatitis C Virus Infection Treatments to Be Discontinued

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The discontinuation is voluntary and is not related to product quality, safety or efficacy.

Hepatitis C-Exposed Infants Not Adequately Screened

Hepatitis C-Exposed Infants Not Adequately Screened

Low screening rate seen at same time as increase in hepatitis C virus prevalence among pregnant women.

Real-Life Renal Outcomes With Sofosbuvir in Chronic Hepatitis C

Real-Life Renal Outcomes With Sofosbuvir in Chronic Hepatitis C

Sofosbuvir-based treatment appears to guarantee renal safety for patients with chronic hepatitis C virus over one year of follow-up.

Methadone Maintenance Therapy Associated With Greater Access to Physician Care in HCV-Positive Drug Users

Methadone Maintenance Therapy Associated With Greater Access to Physician Care in HCV-Positive Drug Users

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The investigators suggest that enrollment in a methadone maintenance therapy program may be helpful in providing access to HCV care in people who inject drugs.

Case Report: Nephrotic Syndrome and Chronic HCV in a 72-Year-Old Woman

Case Report: Nephrotic Syndrome and Chronic HCV in a 72-Year-Old Woman

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A 72-year-old Japanese woman with a 40-year history of lupus nephritis presented with leg edema that had lasted for several weeks.

Screening insufficient for newborns exposed to hepatitis C virus

In this retrospective study, only a fraction of infants receiving well-child care at the study institution were screened for hepatitis C, despite being born to mothers with a known history of hepatitis C virus infection.

Glecaprevir/Pibrentasvir Highly Efficacious for HCV/HIV Coinfection

Glecaprevir/Pibrentasvir Highly Efficacious for HCV/HIV Coinfection

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Study results support the indication of glecaprevir/pibrentasvir as the first 8-week pangenotypic treatment option for HCV/HIV-1 coinfected patients without cirrhosis.

How San Francisco Is Tackling the HIV/HCV and Opioid Epidemics

How San Francisco Is Tackling the HIV/HCV and Opioid Epidemics

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Katie Burk, MPH, presented measures undertaken by the city of San Francisco to provide integrated responses to the concurrent HIV/HCV and opioid public health epidemics.

Hepatitis C Screening Increasing Among Baby Boomers

Hepatitis C Screening Increasing Among Baby Boomers

Future research should develop interventions to increase HCV screening with special focus on groups demonstrating significantly lower screening rates, such as Hispanics and women.

Accelerated Cortical Aging With Alcohol Dependence in HCV-Infected Individuals

Accelerated Cortical Aging With Alcohol Dependence in HCV-Infected Individuals

Alcohol dependence has deleterious effects on frontal cortical volumes that are compounded by hepatitis C virus infection and drug dependence.

Hepatitis C Eradication With DAAs Improves Carotid Atherosclerosis

Hepatitis C Eradication With DAAs Improves Carotid Atherosclerosis

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HCV eradication by DAA improves carotid atherosclerosis in patients with advanced fibrosis and compensated cirrhosis.

HCV-infected kidney donors could save lives

No HCV infection was detected in patients receiving HCV-infected kidneys 12 weeks following treatment.

Case of Psoriasis Remission After Hepatitis C Treatment

Case of Psoriasis Remission After Hepatitis C Treatment

A case of remission of psoriasis after treatment of chronic hepatitis C virus has been described.

Hepatitis C Drug Effective Against Zika Virus in Preclinical Trial

Hepatitis C Drug Effective Against Zika Virus in Preclinical Trial

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The hepatitis C treatment, sofosbuvir was found to be effective against Zika virus in a preclinical trial.

Provider-Pharmacy Collaboration Reduces DAA Initiation Delays in HCV

Provider-Pharmacy Collaboration Reduces DAA Initiation Delays in HCV

Reduced DAA delays and denials for patients with HCV reduced with provider-pharmacy collaboration.

Statewide Increase in Hepatitis C Virus Vertical Transmission Found

Statewide Increase in Hepatitis C Virus Vertical Transmission Found

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State medical surveillance data suggest that the risk for mother-to-infant vertical transmission of hepatitis C virus is increasing.

Treatment Regimens and Recommendations for HIV/HCV Coinfection

Treatment Regimens and Recommendations for HIV/HCV Coinfection

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Experts discuss the management of drug-drug interactions in patients receiving treatment for HIV and HCV coinfection.

High Rates of SVR With Interferon-Free DAA for HCV GT1, Advanced Fibrosis

High Rates of SVR With Interferon-Free DAA for HCV GT1, Advanced Fibrosis

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Ombitasvir/paritaprevir/ritonavir and dasabuvir with or without ribavirin demonstrated high rates of adherence and SVR in different HCV patient subgroups, including patients with advanced fibrosis combined with chronic comorbidities.

Efficacy of Direct-Acting Antivirals for HCV Clearance in Older Adults

Efficacy of Direct-Acting Antivirals for HCV Clearance in Older Adults

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Investigators evaluated whether unfavorable outcomes were prevented once sustained virologic response was achieved in older adults with HCV.

SVR Achieved With Sofosbuvir, Grazoprevir/Elbasvir Plus Ribavirin in HCV

SVR Achieved With Sofosbuvir, Grazoprevir/Elbasvir Plus Ribavirin in HCV

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Safety and efficacy of sofosbuvir plus grazoprevir/elbasvir plus ribavirin was evaluated in individuals who did not achieve sustained virological response on NS5A or NS3-based therapy and RAS failure.

High Rates of SVR With DAAs in HCV/HIV Coninfection

High Rates of SVR With DAAs in HCV/HIV Coninfection

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The advent of direct acting antiviral (DAA) agent therapies has resulted in significant improvements in treatment rates for those with co-infection.

HBV, HCV Increases All-Cause, Liver-Related Mortality in HIV

HBV, HCV Increases All-Cause, Liver-Related Mortality in HIV

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Hepatitis B and hepatitis C may increase mortality risks in patients with HIV.

Efficacy of LDV/SOF for Retreatment of Chronic HCV in SOF-Experienced Patients

Efficacy of LDV/SOF for Retreatment of Chronic HCV in SOF-Experienced Patients

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The highest SVR12 rates were obtained with 12 weeks of LDV/SOF+RBV in noncirrhotic participants and by extending the duration of LDV/SOF treatment to 24 weeks in cirrhotic individuals.

Liver Damage Worse in Women With HBV/HCV Coinfection, Risky Drinking

Liver Damage Worse in Women With HBV/HCV Coinfection, Risky Drinking

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The combined presence of alcohol abuse, HBV, and HCV generates an additive effect on the risk of cirrhosis in women than in men.

The Changing Face of HCV: Role of the Opioid Epidemic

The Changing Face of HCV: Role of the Opioid Epidemic

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The opioid epidemic has fueled the transmission of HCV, particularly among younger persons, who are often unaware of their risks and prevented from receiving timely treatment due to a variety of care barriers, even in settings ideally suited to identifying and treating HCV.

Association Between HBV, HCV and Age-Related Cataracts

Association Between HBV, HCV and Age-Related Cataracts

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High aspartate aminotransferase levels completely mediated the effects of HBV infection on any cataract.

Drinking Coffee Reduces Mortality in HIV/HCV Coinfection

Drinking Coffee Reduces Mortality in HIV/HCV Coinfection

Drinking 3 or more cups of coffee per day halves all-cause mortality risk in patients co-infected with HIV/hepatitis C virus.

Racial Disparities in HCV Incidence and Treatment Outcomes

Racial Disparities in HCV Incidence and Treatment Outcomes

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Racial disparities in HCV treatment outcomes can be partially explained by the differences in underlying immune/genetic characteristics of patients.

FDA Approves Labeling Update for Several HCV Drugs

FDA Approves Labeling Update for Several HCV Drugs

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Updated labeling has been provided for several treatments for hepatitis C virus infections.

Effectiveness of Ledipasvir/Sofosbuvir for Acute HCV Infection in HIV

Effectiveness of Ledipasvir/Sofosbuvir for Acute HCV Infection in HIV

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Study evaluated the optimal duration of ledipasvir/sofosbuvir for the treatment of acute hepatitis C virus (HCV) infection in HIV.

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