HIV/AIDS

Previous Missed Appointments Predict Likelihood of Trend in Patients With HIV

Previous Missed Appointments Predict Likelihood of Trend in Patients With HIV

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In a large, geographically diverse sample of patients engaged in routine HIV primary care, past HIV appointment attendance emerged as the most powerful predictor of future attendance.

International Antiviral Society-USA Updates Recommendations for HIV Treatment and Prevention

International Antiviral Society-USA Updates Recommendations for HIV Treatment and Prevention

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The International Antiviral Society-USA Panel has updated its recommendations for the management and prevention of HIV infection, to reflect the most current data on new treatment regimens and strategies.

Most commonly used HIV drug worldwide not associated with increased risk for suicide in Uganda

No baseline differences observed between patients exposed to efavirenz and nevirapine compared to those never exposed, regarding both depression and suicide.

Low HIV, Syphilis Screening Rates for Adolescents With Pelvic Inflammatory Disease

Low HIV, Syphilis Screening Rates for Adolescents With Pelvic Inflammatory Disease

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New research found low and highly variable rates of HIV and syphilis screening among adolescents with pelvic inflammatory disease.

Low Rates of Syphilis Testing in High-Risk Men Who Are HIV Positive

Low Rates of Syphilis Testing in High-Risk Men Who Are HIV Positive

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Close to one-third of sexually active HIV-positive men who have sex with men (MSM) have not received syphilis screening in the past 12 months.

Addressing Motivations That May Drive PrEP Appeal in MSM

Addressing Motivations That May Drive PrEP Appeal in MSM

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A new theoretical model of understanding (PrEP) use intention in MSM highlights the complexity of decision-making about PrEP in MSM while providing insights into strategies for effective intervention.

Protease Inhibitors May Worsen Outcomes for Patients With HIV, Heart Failure

Protease Inhibitors May Worsen Outcomes for Patients With HIV, Heart Failure

Ritonavir-boosted protease inhibitor therapy is associated with worse outcomes, including death, in patients with HIV and heart failure.

Effects of Alcohol on Frontal White Matter in HIV-Infected Individuals

Effects of Alcohol on Frontal White Matter in HIV-Infected Individuals

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Alcohol use may be associated with microstructural compromise to frontal white matter in patients infected with HIV who do not have dementia and are undergoing antiretroviral therapy.

Guidelines for ART Updated for Those With or at Risk for HIV

Guidelines for ART Updated for Those With or at Risk for HIV

ART recommended for almost all HIV-infected; should be initiated as soon as possible post diagnosis.

Insight Into the HIV Self-Testing Debate

Insight Into the HIV Self-Testing Debate

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Although the CDC recommends routine HIV screening for all people age 13-64 years, numerous barriers to HIV testing in healthcare settings have been identified, including lack of access and fear of stigma and discrimination.

Juluca Maintains Viral Suppression in HIV Patients Through 100 Weeks

Juluca Maintains Viral Suppression in HIV Patients Through 100 Weeks

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The SWORD 1 and SWORD 2 trials enrolled 1027 HIV-infected and virologically suppressed adults; both trials had an early (Day 1 to Week 52) and late (Week 52 to Week 148) switch phase.

New Data Reinforce Efficacy of Symtuza for HIV-1 Treatment

New Data Reinforce Efficacy of Symtuza for HIV-1 Treatment

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In the new subgroup analysis, these results were found to be consistent regardless of baseline regimen.

Increased Use of Truvada for PrEP Linked to Declines in New HIV Cases

Increased Use of Truvada for PrEP Linked to Declines in New HIV Cases

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Findings from the study were presented at the 22nd International AIDS Conference (AIDS 2018) in Amsterdam.

Healthcare Providers Unlikely to Initiate HIV Testing in High Risk Heterosexual Individuals

Healthcare Providers Unlikely to Initiate HIV Testing in High Risk Heterosexual Individuals

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Despite CDC recommendations, about half of all heterosexual adults who are at increased risk for HIV infection and who received health care during a 12-month period were not offered HIV testing, and men were significantly less likely to be offered testing compared with women.

Few HIV Tests Given to Black Men Who Have Sex With Men in South

Few HIV Tests Given to Black Men Who Have Sex With Men in South

New HIV tests in the southern US are provided for black MSM even though they account for a substantial percentage of new diagnoses.

Ten Questions Screen Helps ID Disability in HIV+ Children

Ten Questions Screen Helps ID Disability in HIV+ Children

The Ten Questions (TQ) screen is an effective way to screen HIV-positive children for neurodevelopmental problems in resource-poor areas.

Etravirine Indication Expanded to Include Younger HIV Patients

Etravirine Indication Expanded to Include Younger HIV Patients

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The approval of Intelence for this patient population was based on an open-label, single arm trial (N=20) which showed that the safety and efficacy of etravirine + an optimized background regimen (ritonavir-boosted protease inhibitor in combination with 1 or 2 NRTIs [N=14] and/or combination with an integrase inhibitor [N=7]) was comparable to that observed in adults.

FDA Approves First Darunavir-Based Single-Tablet Regimen for HIV-1 Infection

FDA Approves First Darunavir-Based Single-Tablet Regimen for HIV-1 Infection

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The FDA has approved Symtuza for the treatment of HIV-1 infection in treatment-naive and in virologically suppressed adults.

Mosaic HIV-1 Vaccine Induces Responses in Humans and Monkeys

Mosaic HIV-1 Vaccine Induces Responses in Humans and Monkeys

Mosaic adenovirus serotype 26-based vaccine induces immune responses in humans, rhesus monkeys

Fixed-Dose Bictegravir, Emtricitabine, Tenofovir Alafenamide Is Efficacious HIV-1 Treatment Option

Fixed-Dose Bictegravir, Emtricitabine, Tenofovir Alafenamide Is Efficacious HIV-1 Treatment Option

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The fixed-dose combination of bictegravir, emtricitabine, and tenofovir alafenamide might provide a safe and efficacious option for ongoing treatment of HIV-1 infection

Shared Concerns Regarding Living Organ Donation in HIV

Shared Concerns Regarding Living Organ Donation in HIV

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Concerns and motivations regarding living donor status in people with HIV should be assessed by physicians and independent living donor advocates.

Switch to Dolutegravir Regimen Improves Lipid Profile in HIV+ Patients

Switch to Dolutegravir Regimen Improves Lipid Profile in HIV+ Patients

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Immediate and deferred switching from a boosted protease inhibitor to a dolutegravir regimen in HIV + patients is found to be highly efficacious.

Reduced-Dose Darunavir Effective in Virologically Suppressed HIV-1

Reduced-Dose Darunavir Effective in Virologically Suppressed HIV-1

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A team of investigators sought to assess the safety and efficacy of a reduced dose of darunavir in well-suppressed, treatment-experienced individuals with HIV.

Increased Risk for Osteopenia, Osteoporosis in HIV Highlights Need for BMD Monitoring

Increased Risk for Osteopenia, Osteoporosis in HIV Highlights Need for BMD Monitoring

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Investigators used DXA scans to assess the progression to osteopenia and osteoporosis in individuals with HIV.

Missed Opportunities for HIV Diagnosis Among Those at Risk

Missed Opportunities for HIV Diagnosis Among Those at Risk

Considerable numbers of MSM and persons who inject drugs who are unaware of their HIV infection report missed opportunities for diagnosis.

Telling Children Their HIV Status: Interview With Dr Elizabeth Lowenthal

Telling Children Their HIV Status: Interview With Dr Elizabeth Lowenthal

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Infectious Disease Advisor speaks with Elizabeth D. Lowenthal, MD, about the challenges associated with revealing HIV seropositive status to children.

Risk Prediction Scores Aid Management of Chronic Kidney Disease in HIV

Risk Prediction Scores Aid Management of Chronic Kidney Disease in HIV

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Investigators sought to assess the effectiveness of tools to predict the risk of chronic kidney disease in individuals with HIV.

Assessment of Chronic Opioid Therapy in People Living With HIV

Assessment of Chronic Opioid Therapy in People Living With HIV

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Appropriate monitoring and implementation of guidelines for opioid therapy is lacking in patients living with HIV.

Recognizing Precipitators of Virologic Failure in Youth With HIV

Recognizing Precipitators of Virologic Failure in Youth With HIV

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Researchers assessed factors contributing to virologic failure in youth with perinatally acquired HIV infection receiving highly active antiretroviral therapy.

Multilevel Interventions Needed to Improve Barriers to PrEP

Multilevel Interventions Needed to Improve Barriers to PrEP

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The final review included 47 articles that fell under 1 of the following categories: primary data on cognitive variables of providers; data on cognitive variables and perspectives of individuals at risk for HIV infection; literature on PrEP implementation; and case studies of PrEP demonstration and implementation projects.

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