HIV

Low Rates of Syphilis Testing in High-Risk Men Who Are HIV Positive

Low Rates of Syphilis Testing in High-Risk Men Who Are HIV Positive

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Close to one-third of sexually active HIV-positive men who have sex with men (MSM) have not received syphilis screening in the past 12 months.

Effects of Alcohol on Frontal White Matter in HIV-Infected Individuals

Effects of Alcohol on Frontal White Matter in HIV-Infected Individuals

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Alcohol use may be associated with microstructural compromise to frontal white matter in patients infected with HIV who do not have dementia and are undergoing antiretroviral therapy.

New Data Reinforce Efficacy of Symtuza for HIV-1 Treatment

New Data Reinforce Efficacy of Symtuza for HIV-1 Treatment

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In the new subgroup analysis, these results were found to be consistent regardless of baseline regimen.

Etravirine Indication Expanded to Include Younger HIV Patients

Etravirine Indication Expanded to Include Younger HIV Patients

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The approval of Intelence for this patient population was based on an open-label, single arm trial (N=20) which showed that the safety and efficacy of etravirine + an optimized background regimen (ritonavir-boosted protease inhibitor in combination with 1 or 2 NRTIs [N=14] and/or combination with an integrase inhibitor [N=7]) was comparable to that observed in adults.

FDA Approves First Darunavir-Based Single-Tablet Regimen for HIV-1 Infection

FDA Approves First Darunavir-Based Single-Tablet Regimen for HIV-1 Infection

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The FDA has approved Symtuza for the treatment of HIV-1 infection in treatment-naive and in virologically suppressed adults.

Fixed-Dose Bictegravir Regimen: A Safe Alternative in Adults With HIV-1

Fixed-Dose Bictegravir Regimen: A Safe Alternative in Adults With HIV-1

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Fixed-dose bictegravir, emtricitabine, and tenofovir alafenamide might be a safe and efficacious alternative to continued boosted protease inhibitor therapy in patients with HIV-1

Shared Concerns Regarding Living Organ Donation in HIV

Shared Concerns Regarding Living Organ Donation in HIV

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Concerns and motivations regarding living donor status in people with HIV should be assessed by physicians and independent living donor advocates.

Increased Risk for Osteopenia, Osteoporosis in HIV Highlights Need for BMD Monitoring

Increased Risk for Osteopenia, Osteoporosis in HIV Highlights Need for BMD Monitoring

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Investigators used DXA scans to assess the progression to osteopenia and osteoporosis in individuals with HIV.

CDC: Updated Recommendations for Latent TB Infection Treatment

CDC: Updated Recommendations for Latent TB Infection Treatment

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The CDC has issued updated recommendations regarding the use of 3HP for the treatment of latent tuberculosis.

Missed Opportunities for HIV Diagnosis Among Those at Risk

Missed Opportunities for HIV Diagnosis Among Those at Risk

Considerable numbers of MSM and persons who inject drugs who are unaware of their HIV infection report missed opportunities for diagnosis.

Telling Children Their HIV Status: Interview With Dr Elizabeth Lowenthal

Telling Children Their HIV Status: Interview With Dr Elizabeth Lowenthal

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Infectious Disease Advisor speaks with Elizabeth D. Lowenthal, MD, about the challenges associated with revealing HIV seropositive status to children.

Efavirenz Not Assciated With Increased Depression Risk Compared With Nevirapine

Efavirenz Not Assciated With Increased Depression Risk Compared With Nevirapine

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The researchers believe this study is the first to detect a statistically significant, unexpected inverse association between efavirenz use and depression.

Risk Prediction Scores Aid Management of Chronic Kidney Disease in HIV

Risk Prediction Scores Aid Management of Chronic Kidney Disease in HIV

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Investigators sought to assess the effectiveness of tools to predict the risk of chronic kidney disease in individuals with HIV.

Assessment of Chronic Opioid Therapy in People Living With HIV

Assessment of Chronic Opioid Therapy in People Living With HIV

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Appropriate monitoring and implementation of guidelines for opioid therapy is lacking in patients living with HIV.

Unplanned Pregnancies Prevalent Among HIV-Positive Women

Unplanned Pregnancies Prevalent Among HIV-Positive Women

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Researchers examined unplanned pregnancies and contraceptive use among HIV-positive women in a cross-sectional study.

Multilevel Interventions Needed to Improve Barriers to PrEP

Multilevel Interventions Needed to Improve Barriers to PrEP

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The final review included 47 articles that fell under 1 of the following categories: primary data on cognitive variables of providers; data on cognitive variables and perspectives of individuals at risk for HIV infection; literature on PrEP implementation; and case studies of PrEP demonstration and implementation projects.

Social Network Support Decreases Risk for HIV Seroconversion in Black MSM

Social Network Support Decreases Risk for HIV Seroconversion in Black MSM

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The increased presence of social network support may decrease the risk for HIV seroconversion in black MSM.

Higher Rate of Mother-to-Child Transmission Among Women With Perinatal HIV

Higher Rate of Mother-to-Child Transmission Among Women With Perinatal HIV

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Although rates of mother-to-child transmission of HIV have decreased as a result of effective treatments and protective delivery and feeding practices, transmission does persist.

ART Simplification Does Not Affect Systemic Inflammation in Virologically Suppressed HIV

ART Simplification Does Not Affect Systemic Inflammation in Virologically Suppressed HIV

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Simplification to atazanavir/ritonavir plus lamivudine as a maintenance therapy has the same effect on markers of systemic inflammation biomarkers as triple therapy.

Long-Term Viral Suppression May Decrease Cancer Risk in HIV+ Individuals

Long-Term Viral Suppression May Decrease Cancer Risk in HIV+ Individuals

Antiretroviral therapy resulting in long-term viral suppression of HIV may contribute to cancer prevention.

HIV Pre-Exposure Prophylaxis Linked to Drop in Condom Use

HIV Pre-Exposure Prophylaxis Linked to Drop in Condom Use

For gay and bisexual men, an increase in HIV PrEP is associated with a reduction in condom use.

Closer Monitoring Recommended for Older Patients Treated With Dolutegravir for HIV

Closer Monitoring Recommended for Older Patients Treated With Dolutegravir for HIV

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The maximum concentration of the integrase inhibitor dolutegravir was significantly higher in older people living with HIV.

Prezcobix Not Recommended During Pregnancy, According to Updated Labeling

Prezcobix Not Recommended During Pregnancy, According to Updated Labeling

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The labeling now states that Prezcobix is not recommended for use in pregnant women due to substantially lower exposures of the active ingredients, darunavir and cobicistat, during pregnancy.

Cancer Treatment Disparities in Elderly HIV-Infected Americans Warrant Attention

Cancer Treatment Disparities in Elderly HIV-Infected Americans Warrant Attention

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Cancer treatment rates for HIV-infected seniors were lowest among the younger subset of patients, who would likely benefit most from treatment in terms of life expectancy.

Cumulative Ritonavir-Boosted Darunavir Use May Be Associated With Increased CVD Risk

Cumulative Ritonavir-Boosted Darunavir Use May Be Associated With Increased CVD Risk

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An increased risk for cardiovascular disease with ritonavir-boosted darunavir regimens for HIV was identified in a prospective multicenter study.

Psychosocial Interventions in HIV: How Best to Support HIV-Positive Patients

Psychosocial Interventions in HIV: How Best to Support HIV-Positive Patients

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Mental health professionals supporting patients living with HIV need to make space for their patients to process the emotional effect of their diagnosis, but not to make assumptions about what it means to them.

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

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A substantial proportion of these individuals diagnosed with HIV, psychiatric disorders, and substance use disorders are out of care and urgently require intervention.

Continuous Medicaid Coverage Essential for People Living With HIV

Continuous Medicaid Coverage Essential for People Living With HIV

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Implementing initiatives to maintain Medicaid enrollment and to expedite Medicaid reenrollment and having alternate resources available in gaps are important to ensure continuous antiretroviral therapy to optimize HIV outcomes.

Bilirubin Levels May Be Predictive of Cardiovascular Disease in HIV

Bilirubin Levels May Be Predictive of Cardiovascular Disease in HIV

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Bilirubin appeared to be inversely associated with cardiovascular disease in individuals with HIV enrolled in the Veterans Aging Cohort Study.

COPD Frequently Misdiagnosed, Undiagnosed in Individuals Infected With HIV

COPD Frequently Misdiagnosed, Undiagnosed in Individuals Infected With HIV

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In this study, researchers examined the appropriateness of diagnosis and treatment of chronic obstructive pulmonary disease in individuals with and without HIV.

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