HIV

Cardiovascular Disease in Persons With HIV Infection

Cardiovascular Disease in Persons With HIV Infection

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Persons living with HIV infection have a higher risk for cardiovascular disease; use of some antiretroviral agents can exacerbate this risk.

Atazanavir/Ritonavir Plus Lamivudine is as Safe, Effective as Triple Therapy

Atazanavir/Ritonavir Plus Lamivudine is as Safe, Effective as Triple Therapy

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Dual combination ART with atazanavir/ritonavir plus lamivudine demonstrated similar efficacy and safety as atazanavir/ritonavir plus 2 NRTIs at 48 weeks in the ATLAS-M trial.

Two HIV Studies Reinforce Guidelines Recommending TAF-Based Regimens

Two HIV Studies Reinforce Guidelines Recommending TAF-Based Regimens

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Switching to TAF-based regimen was non-inferior to continuing TDF-based regimen in maintaining viral suppression.

Routine HIV Testing Cost-Effective in Antenatal Settings

Routine HIV Testing Cost-Effective in Antenatal Settings

Data from the reviewed studies showed cost savings between $5,761.20 and $3.69 million per case of previously undiagnosed maternal HIV-positive infection prevented.

Increasing Risk of HIV Among Men Who Have Sex With Men

Increasing Risk of HIV Among Men Who Have Sex With Men

Belief that treatments prevent HIV has increased condomless anal sex in both HIV positive men and men who had not tested HIV positive.

Liver Cancer Rates With Interferon-Free Regimens in HIV/HCV

Liver Cancer Rates With Interferon-Free Regimens in HIV/HCV

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The incidence of hepatocellular carcinoma after sustained virological response has not increased with the widespread use of all oral direct antivirals regimens as suggested in previous studies, according to a new study.

French Study Points to Eradication of HIV-HCV Coinfection

French Study Points to Eradication of HIV-HCV Coinfection

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Prevalence of active HIV-HCV coinfection may decrease to 1.1% in France over the next decade.

Latent HIV May Exist in Both Resting and Non-Resting CD4 T cells

Latent HIV May Exist in Both Resting and Non-Resting CD4 T cells

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Researchers quantify inducible virus in long-term suppressed patients that was missed by the gold standard assay that measures the latent reservoir.

New Study Links Darunavir to Increased Risk for CVD

New Study Links Darunavir to Increased Risk for CVD

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Study looking at the use of 2 frequently used protease inhibitors (atazanavir and darunavir) is suggesting that cumulative use of darunavir may be independently associated with a small but gradually increasing cardiovascular disease (CVD) risk.

Early ART Reduces Bacterial Infection Risk in HIV With High CD4 Counts

Early ART Reduces Bacterial Infection Risk in HIV With High CD4 Counts

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Immediate antiretroviral therapy lowers the risk for severe bacterial infections in patients with HIV and high CD4. This effect may be mediated by increases in CD4 count, but not by increases in neutrophil count.

Canadian Man Infected With HIV Despite PrEP Adherence

Canadian Man Infected With HIV Despite PrEP Adherence

A 43-year-old Canadian man was infected with a strain of HIV that had become resistant to emtricitabine and tenofovir disoproxil fumarate.

Vaginal Microbiota May Affect Tenofovir Applied Intravaginally

Vaginal Microbiota May Affect Tenofovir Applied Intravaginally

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New study suggests that the vaginal microbiome may modify tenofovir delivery.

Investigational 2-Drug HIV Regimen Showing Promise

Investigational 2-Drug HIV Regimen Showing Promise

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Investigational combination of a once-daily 2-drug regimen of dolutegravir plus rilpivirine may be as effective as a 3- or 4-drug current antiretroviral regimen in HIV-1-infected patients.

Multiple Viral Load Value Testing May Better Inform HIV Transmission Potential

Multiple Viral Load Value Testing May Better Inform HIV Transmission Potential

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Viral loads can fluctuate over time depending on patients' access and response to HIV treatment, their medication adherence behavior, and care status.

Potential New Drug Option for Treatment-Naïve HIV-1 Patients

Potential New Drug Option for Treatment-Naïve HIV-1 Patients

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The once-daily dosing doravirine appears to have similar efficacy and to be non-inferior to once-daily ritonavir-boosted darunavir (DRV+r) on a background of 2 NRTIs in HIV-1 treatment-naïve adults.

Investigational HIV Monoclonal Antibody Effective in Multiple Drug Resistant HIV-1

Investigational HIV Monoclonal Antibody Effective in Multiple Drug Resistant HIV-1

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New phase 3 results were reported from a single arm, multicenter study evaluating the safety and effectiveness of ibalizumab in patients infected with multi-drug resistant HIV-1.

Transmission Route-Specific HIV-1 Variant Selection Identified

Transmission Route-Specific HIV-1 Variant Selection Identified

Viral transmission through breastfeeding appears to select for viral variants with fewer potential glycosylation sites in gp41.

Achieving Optimal Neurodevelopmental Outcomes in HIV-Infected Infants

Achieving Optimal Neurodevelopmental Outcomes in HIV-Infected Infants

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HIV-infected infants who have a good response to ART are likely to recapture missed developmental milestones compared with uninfected infants but are unlikely to achieve full recovery.

Does Diabetic Medication Impact HbA1c in HIV-Infected Patients With T2D?

Does Diabetic Medication Impact HbA1c in HIV-Infected Patients With T2D?

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Glycemic response was independent of diabetic medication prescribed among HIV-infected adults with T2D, according to a study.

Higher Rates of Diabetes Mellitus Seen in Patients With HIV

Higher Rates of Diabetes Mellitus Seen in Patients With HIV

Diabetes mellitus in HIV-infected adults may develop at an earlier age and in the absence of obesity when compared to the general adult population, according to a study.

More HIV Testing Needed in Patients With Severe Mental Illness

More HIV Testing Needed in Patients With Severe Mental Illness

People with bipolar disorder, schizophrenia, or major depression with psychosis may be up to 15 times more likely to be HIV positive compared to the general population, according to a study.

Reducing Diabetes Risk Key to Eradicating HCV in Coinfected Patients

Reducing Diabetes Risk Key to Eradicating HCV in Coinfected Patients

Sustained viral response correlated with a significant decrease in the risk of diabetes mellitus and a trend towards decrease in chronic renal failure, according to a study.

Stribild Expanded for Use in Children With HIV

Stribild Expanded for Use in Children With HIV

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Stribild has been updated to include use in patients aged ≥12 years weighing ≥35kg.

Advances in the Battle Against HIV/AIDS to be Highlighted at CROI 2017

Advances in the Battle Against HIV/AIDS to be Highlighted at CROI 2017

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Vaccines against HIV/AIDS enter a new era.

Multiple Updates for Atazanavir and Cobicistat HIV Combination Tx

Multiple Updates for Atazanavir and Cobicistat HIV Combination Tx

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Evotaz label has been updated to include data from Trial 114 including updates to the drug interactions and specific populations sections.

Should the FDA Lift the Ban on Blood Donations From MSM?

Should the FDA Lift the Ban on Blood Donations From MSM?

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Critics of the FDA's current restriction on blood donation from MSM argue that it is unnecessary and discriminatory, and propose a policy based on individual risk rather than sexual orientation.

Vitamin D Deficiency Decreases Statin Efficacy in HIV

Vitamin D Deficiency Decreases Statin Efficacy in HIV

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Vitamin D supplementation may be warranted for deficient patients with HIV who are initiating statin therapy.

Blacks Still Disproportionately Affected by HIV/AIDS in US

Blacks Still Disproportionately Affected by HIV/AIDS in US

Improving health outcomes for blacks living with HIV infection is necessary to reduce HIV in the United States.

HIV Positive MSM Receiving ART at Higher Risk for Syphilis

HIV Positive MSM Receiving ART at Higher Risk for Syphilis

Highly active antiretroviral therapy may boost susceptibility to the bacterium that causes syphilis.

Antidepressant Treatment Lacking in Patients With HIV

Antidepressant Treatment Lacking in Patients With HIV

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Findings show that approximately 2 in 5 HIV patients are in need of depression treatment with only about half of these patients actually receiving antidepressant treatment.

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