Nosocomial Infections

Feature Article

Strategies for Reducing Hospital-Acquired Infections

Strategies for Reducing Hospital-Acquired Infections

Study finds that patients were 10% to 30% less likely to acquire a multidrug-resistant organism or C difficile if enhanced disinfection strategies were used in hospitals.

The relative risk for healthcare-associated infections has decreased in the last 15 years due to improvements in awareness of risk associated with devices, infection control, and evidence-based practice regarding use of devices.

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Shortage of Norepinephrine Linked to Increase in Septic Shock Deaths

Shortage of Norepinephrine Linked to Increase in Septic Shock Deaths

Hospitals see higher rate of in-hospital mortality from septic shock after norepinephrine shortage.

FDA: QDIP Status for Post-Surgical Sternal Infection Antibiotic Reservoir

FDA: QDIP Status for Post-Surgical Sternal Infection Antibiotic Reservoir

The FDA has granted Qualified Infectious Disease Product (QIDP) to D-PLEX (Doxycycline/Polymer-Lipid Encapsulation Matrix; PolyPid), a secured antibiotic drug reservoir for the local prevention and treatment of surgical infections.

Letermovir Prevents CMV Infection in Bone Marrow Transplant Recipients

Letermovir Prevents CMV Infection in Bone Marrow Transplant Recipients

Phase 3 study showed positive results for Merck's letermovir in prevention of CMV infection in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant.

Pacemaker Increases Infective Endocarditis Risk in Aortic Valve Replacement

Pacemaker Increases Infective Endocarditis Risk in Aortic Valve Replacement

Researchers looked at the role of concomitant pacemaker presence and the risk of infective endocarditis in patients undergoing aortic valve replacement.

Hospital Room Floors May be Unrecognized Pathogen Dissemination Source

Hospital Room Floors May be Unrecognized Pathogen Dissemination Source

Disinfecting surfaces is key to preventing nosocomial transmission of pathogens such as C difficile, MRSA, and vancomycin-resistant enterococci.

Hospital Sinks May Spread Multidrug-Resistant Bacteria

Hospital Sinks May Spread Multidrug-Resistant Bacteria

After colonizing in drains, Escherichia coli slowly started to grow toward the sink strainers, growing 1 inch each day, researchers found in a study.

SOFA Score Better Predicts In-Hospital Mortality for Adults in ICU

SOFA Score Better Predicts In-Hospital Mortality for Adults in ICU

SOFA score has greater prognostic accuracy for in-hospital mortality than SIRS criteria or the qSOFA score.

No Effect of Alkalosis on Mortality in ICU Patients With Sepsis

No Effect of Alkalosis on Mortality in ICU Patients With Sepsis

Metabolic alkalosis did not have any effect on 30-day and 12-month mortality in patients with severe sepsis or septic shock.

Improved Catheter Safety Measures Reduce Bloodstream Infections

Improved Catheter Safety Measures Reduce Bloodstream Infections

Interventions related to central venous catheters were, on average, associated with 57% fewer bloodstream infections and substantial savings to hospitals.

Quick SOFA Better Than SIRS, Severe Sepsis in Identifying Mortality Risk

Quick SOFA Better Than SIRS, Severe Sepsis in Identifying Mortality Risk

Quick SOFA had greater prognostic accuracy for in-hospital mortality than did either SIRS or severe sepsis.

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