Combination β-lactam, Macrolide Pneumonia Therapy in Children Not More Effective
Judicious antibiotic selection is critical to slowing the progression of antimicrobial resistance, and excessive use of macrolides has been an important target.
Previous antibiotic use and mechanical invasive ventilation were risk factors for multidrug-resistant pathogens in hospital-associated or ventilator-associated pneumonia.
A negative chest radiograph accurately excludes pneumonia in the majority of children.
The full findings from the study will be presented at a future scientific conference; Merck plans to include the data in a supplemental New Drug Application for Zerbaxa which will ...