Pneumonia

Efficacy of Procalcitonin-Guided Antimicrobial Stewardship Initiative for Diagnosing Pneumonia

Efficacy of Procalcitonin-Guided Antimicrobial Stewardship Initiative for Diagnosing Pneumonia

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Implementation of a procalcitonin diagnostic algorithm improves diagnostic yield and reduces hospital length of stay in bacterial pneumonia.

Minorities With Low Income and Poor Education Receive Lower Uptake of PCV13

Minorities With Low Income and Poor Education Receive Lower Uptake of PCV13

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Multiple disparities exist in rates of adult vaccination for 13-valent pneumococcal conjugate vaccine.

Efficacy of Delafloxacin in Treating Community-Acquired Bacterial Pneumonia

Efficacy of Delafloxacin in Treating Community-Acquired Bacterial Pneumonia

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The efficacy of delafloxacin in treating Streptococcus pneumoniae, Haemophilius influenzae, and Moraxella catarrhalis isolates was examined.

Macrolides Superior to Beta-Lactams in Pediatric Community-Acquired Pneumonia

Macrolides Superior to Beta-Lactams in Pediatric Community-Acquired Pneumonia

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Macrolides, despite inferior anti-pneumococcal activity, are the most commonly prescribed antibiotic class for CAP in Children.

Updated Guidelines for Management of Hospital-Acquired/Ventilator-Associated Pneumonia

Updated Guidelines for Management of Hospital-Acquired/Ventilator-Associated Pneumonia

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An international panel of experts applied the GRADE system and choose 7 PICO questions to generate recommendations for HAP/VAP.

No Significant Difference in Community-Acquired Pneumonia Tx Outcomes in HIV Immunosuppression

No Significant Difference in Community-Acquired Pneumonia Tx Outcomes in HIV Immunosuppression

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Adults with community-acquired pneumococcal pneumonia who are HIV-immunosuppressed had the same prognosis and outcomes with standardized treatment.

Labored Breathing, Hypoxemia May Indicate Pneumonia in Children

Labored Breathing, Hypoxemia May Indicate Pneumonia in Children

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Difficulty breathing and hypoxemia may be a better indication of pneumonia in children.

Otopathogen Prevalence Altered Since Pneumococcal Vaccine Introduction

Otopathogen Prevalence Altered Since Pneumococcal Vaccine Introduction

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A new longitudinal study updates the epidemiology of acute otitis media in the decade after pneumococcal conjugate vaccine introduction.

Increased CVD Risk Persists for Years After Treatment for Sepsis or Pneumonia

Increased CVD Risk Persists for Years After Treatment for Sepsis or Pneumonia

Cardiovascular disease risks persist for years after sepsis or pneumonia.

Time to Blood Culture Positivity Predicts Pneumonia Severity and Outcome

Time to Blood Culture Positivity Predicts Pneumonia Severity and Outcome

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Time to blood culture positivity was directly associated with disease severity and outcomes in bacteremic pneumococcal pneumonia.

Increased Risk of Pneumococcal Infection Linked to Celiac Disease

Increased Risk of Pneumococcal Infection Linked to Celiac Disease

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Researchers conducted a systematic review of 3 manuscripts, including a total of 50,547 patients with celiac disease.

Risk of Cardiovascular Disease in Men With Sepsis, Pneumonia

Risk of Cardiovascular Disease in Men With Sepsis, Pneumonia

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Men who have sepsis or pneumonia have a higher risk of cardiovascular disease.

Clinical Update: Community-Acquired Pneumonia Following Sepsis

Clinical Update: Community-Acquired Pneumonia Following Sepsis

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The quick Sepsis-Related Organ Failure Assessment (qSOFA) clinical tool was superior to SIRS criteria for the evaluation of in-hospital mortality.

Chasing Serotype Replacement in Pneumococcal Pneumonia

Chasing Serotype Replacement in Pneumococcal Pneumonia

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Increasing rates of non-pneumococcal conjugate vaccine 13 serotypes of invasive pneumococcal disease present a new challenge to the global containment of the infection.

VZV-Related CAP Linked to Significant Mortality, Morbidity Rates

VZV-Related CAP Linked to Significant Mortality, Morbidity Rates

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Varicella-zoster virus-related community-acquired pneumonia can be linked to significant rates of morbidity and mortality in adults.

Challenges in Managing Hospital-Acquired Pneumonia

Challenges in Managing Hospital-Acquired Pneumonia

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Diagnosis is one of the primary difficulties in managing hospital acquired pneumonia.

Single-Dose PCV13 Immunogenic, Safe in Pediatric Oncology

Single-Dose PCV13 Immunogenic, Safe in Pediatric Oncology

A single-dose 13-valent pneumococcal conjugate vaccine (PCV13) was found to be safe and immunogenic for pediatric oncology patients.

Efficacy of Antibiotics for Community-Acquired Pneumonia Evaluated

Efficacy of Antibiotics for Community-Acquired Pneumonia Evaluated

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Study finds that over one-fifth of those prescribed an antibiotic for community-acquired pneumonia experience treatment failure.

Higher Risk for Pneumonia in HIV Does Not Mean Worse Outcomes

Higher Risk for Pneumonia in HIV Does Not Mean Worse Outcomes

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A Barcelona study found that patients with HIV required no special treatment for pneumonia compared with healthy individuals.

Pneumonia Risk Higher in Asthma Patients Using Inhaled Corticosteroid

Pneumonia Risk Higher in Asthma Patients Using Inhaled Corticosteroid

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Use of inhaled corticosteroids is linked to increased risk of pneumonia in patents with asthma.

Can Neutrophil-to-Lymphocyte Ratio Predict Mortality in CAP?

Can Neutrophil-to-Lymphocyte Ratio Predict Mortality in CAP?

Neutrophil-to-lymphocyte ratio (NLR) can predict 30-day mortality for elderly adults with community-acquired pneumonia (CAP).

AATS: Guidelines for Empyema Management Released

AATS: Guidelines for Empyema Management Released

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The American Association for Thoracic Surgery has release guidelines on the treatment of empyema from complications of pneumonia.

Higher Risk of Community-Acquired Pneumonia With Certain T2D Drugs

Higher Risk of Community-Acquired Pneumonia With Certain T2D Drugs

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Patients with type 2 diabetes may be at greater risk of developing community-acquired pneumonia when using thiazolidinediones with metformin compared to treatment with a sulfonylurea and metformin.

Benzodiazepine Use Increases Pneumonia Risk in Alzheimer Disease

Benzodiazepine Use Increases Pneumonia Risk in Alzheimer Disease

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Risk for pneumonia should be considered when weighing the benefits and risks of benzodiazepines in patients with Alzheimer disease.

Pneumonia Rate in Children Decreased With PCV10 Vaccine

Pneumonia Rate in Children Decreased With PCV10 Vaccine

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The rate of pneumonia decreased with the introduction of the 10-valent pneumococcal conjugate vaccine (PCV10) in vaccine-eligible children and older, unvaccinated children.

Treatment of CAP: Phase 3 Results of Novel Tetracycline

Treatment of CAP: Phase 3 Results of Novel Tetracycline

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Paratek announced positive outcomes for their phase 3 trial of omadacycline for treating community-acquired bacterial pneumonia.

Pneumonia Risk in Dementia Increases With Proton Pump Inhibitor Use

Pneumonia Risk in Dementia Increases With Proton Pump Inhibitor Use

Age, male gender, underlying cerebrovascular disease, chronic pulmonary disease, congestive heart failure, diabetes mellitus, and usage of antipsychotics were independent risk factors of pneumonia among dementia patients with PPI usage.

High Cardiac Troponin Levels Predict Mortality in CAP

High Cardiac Troponin Levels Predict Mortality in CAP

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Elevated cardiac troponin levels were highly predictive of both in-hospital and long-term mortality in patients admitted for community-acquired pneumonia (CAP).

Rhinovirus Pneumonia Increases Mortality in Stem Cell Transplant Recipients

Rhinovirus Pneumonia Increases Mortality in Stem Cell Transplant Recipients

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Rhinovirus detection in the lower respiratory tract had high mortality rates comparable to viral pneumonia associated with other well-established respiratory viruses.

Diagnosing Pneumonia: Ultrasound More Accurate Than Radiology

Diagnosing Pneumonia: Ultrasound More Accurate Than Radiology

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Point of care lung ultrasound is an accurate tool for the diagnosis of pneumonia.

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