Prevention

High-Dose Influenza Vaccination May Benefit Transplant Recipients

High-Dose Influenza Vaccination May Benefit Transplant Recipients

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Double-dose influenza vaccine is safe and may increase antibody response in solid-organ transplant recipients

Vitamin C Treatment May Be Beneficial for Sepsis, But Duration and Dose Unclear

Vitamin C Treatment May Be Beneficial for Sepsis, But Duration and Dose Unclear

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Vitamin C was associated with lower mortality rates, shorter lengths of ICU stay, and shorter durations of vasopressor use in patients with sepsis.

Eravacycline Now Available for Treating Complicated Intra-Abdominal Infections

Eravacycline Now Available for Treating Complicated Intra-Abdominal Infections

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As Xerava is a fully-synthetic fluorocycline antibacterial that is structurally similar to tetracyclines, treatment is contraindicated in patients with known hypersensitivity to tetracycline-class antibacterial drugs.

Prophylaxis With TMP-SMX Did Not Alter Risk for Non-UTI Infections

Prophylaxis With TMP-SMX Did Not Alter Risk for Non-UTI Infections

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Daily prophylaxis with TMP-SMX was not associated with change in risk for skin and soft tissue or sino-pulmonary infections, or pharyngitis in children.

Pneumococcal <i>H Influenzae</i> Protein D Conjugate Vaccine Effective in Children

Pneumococcal H Influenzae Protein D Conjugate Vaccine Effective in Children

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The burden of childhood and infant pneumonia can be effectively reduced through the use of the pneumococcal Haemophilus influenzae protein D conjugate vaccine.

Statins Increase Risk for Medically Attended Acute Respiratory Illness

Statins Increase Risk for Medically Attended Acute Respiratory Illness

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Elderly patients who have been inoculated with the influenza vaccine and who also use a statin are at a greater risk for medically attended acute respiratory illness.

Prophylactic Antibiotics May Not Be Helpful After Acute Stroke

Prophylactic Antibiotics May Not Be Helpful After Acute Stroke

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In acute ischemic or hemorrhagic stroke, prophylactic antibiotics reduce the overall infection rate, but do not reduce the risk for pneumonia, death, or dependency.

Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

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Repeated exposure to the influenza virus affects antibody quantity and quality, and strains selected for seasonal vaccines may not provide coverage sufficient for individuals frequently infected and/or vaccinated.

Three-Quarters of Health Care Workers Got Flu Shot Last Year

Three-Quarters of Health Care Workers Got Flu Shot Last Year

Just over three-quarters of health care personnel received a flu vaccine last season.

FDA Approves HPV Vaccine for People Through Age 45

FDA Approves HPV Vaccine for People Through Age 45

US Food and Drug Administration approval of the Gardasil 9 HPV vaccine has been expanded to include people ages 27 through 45.

Novel Blood Test for Gastroenteritis-Induced Irritable Bowel Syndrome

Novel Blood Test for Gastroenteritis-Induced Irritable Bowel Syndrome

The test works by measuring levels of anti-cytolethal distending toxin B (CdtB) and anti-vinculin, 2 biomarkers of post-infectious IBS-D and IBS-M.

Novel Intranasal Influenza Vaccine Shows Tolerability, Safety, and High Immune Response

Novel Intranasal Influenza Vaccine Shows Tolerability, Safety, and High Immune Response

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NasoVAX, an adenovirus-based intranasal flu vaccine, shows tolerability, safety, and higher cellular immune response compared to an injectable vaccine.

High-Risk HPV Infection Linked With Cardiovascular Disease in Women

High-Risk HPV Infection Linked With Cardiovascular Disease in Women

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Women with high-risk human papillomavirus are at higher risk for developing cardiovascular disease than women without high-risk HPV

Omadacycline Approved for  Community-Acquired Bacterial Pneumonia, Skin Infections

Omadacycline Approved for Community-Acquired Bacterial Pneumonia, Skin Infections

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The approval was based on Phase 3 data from 2 studies in ABSSSI, where treatment with Nuzyra was compared with linezolid, and 1 study in CABP comparing Nuzyra with moxifloxacin. Across all 3 trials, Nuzyra was found to be effective and generally safe and well-tolerated.

Increasing Water Intake Can Reduce Cystitis Recurrence

Increasing Water Intake Can Reduce Cystitis Recurrence

For women at high risk for recurrence, increasing water intake can prevent recurrence.

Vitamin D Deficiency Associated With Sepsis Mortality

Vitamin D Deficiency Associated With Sepsis Mortality

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Vitamin D deficiency is associated with increased risk for sepsis mortality in postmenopausal women, which was seen in all ages.

Patient Develops Acquired Hemophilia After Treatment With Levofloxacin

Patient Develops Acquired Hemophilia After Treatment With Levofloxacin

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A recent report published in the Journal of Pharmacy Practice describes the case of a 75-year-old female patient who developed acquired hemophilia following levofloxacin administration.

WHO Reports High Risk That Ebola May Spread From Congo

WHO Reports High Risk That Ebola May Spread From Congo

WHO reports two cases of the deadly virus were confirmed near the border with Uganda.

Prescribing Antibiotics Shortens Telemedicine Visits for Respiratory Tract Infections

Prescribing Antibiotics Shortens Telemedicine Visits for Respiratory Tract Infections

These findings may highlight physician difficulty explaining to patients why antibiotics are not required.

80,000 Americans Died From Influenza Over Last Year

80,000 Americans Died From Influenza Over Last Year

2017 to 2018 flu strains affect the very young and elderly especially signifantly; poor vaccine/strain match-up

Improving Rates of Combination Pneumococcal Vaccination in Patients With SLE

Improving Rates of Combination Pneumococcal Vaccination in Patients With SLE

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Pneumococcal vaccination rates in patients with systemic lupus erythematosus improved significantly after the implementation of a multifaceted intervention at a rheumatology practice.

Integrated Intervention Engages PLWHIV who Inject Drugs

Integrated Intervention Engages PLWHIV who Inject Drugs

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A flexible, scalable intervention increases antiretroviral therapy and medication-assisted treatment use while reducing mortality in people who inject drugs.

Cobas Diagnostic Assay Shows High Accuracy for Chlamydia, Gonorrhea

Cobas Diagnostic Assay Shows High Accuracy for Chlamydia, Gonorrhea

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The cobas CT/NG v2.0 test for Chlamydia trachomatis and Neisseria gonorrhoeae performed well when tested for sensitivity and specificity.

New Assay Efficacious for Diagnosing Extrapulmonary Tuberculosis and Rifampin Resistance

New Assay Efficacious for Diagnosing Extrapulmonary Tuberculosis and Rifampin Resistance

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Xpert MTB/RIF may be helpful for confirming a diagnosis of extrapulmonary tuberculosis and can accurately detect resistance to rifampicin.

High Level of Population-Wide Immunity Enhances Disappearance of Sabin-2 Poliovirus

High Level of Population-Wide Immunity Enhances Disappearance of Sabin-2 Poliovirus

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A high level of population-wide immunity at the time the oral polio vaccine 2 was withdrawn has helped to enhance the disappearance of Sabin-2 vaccine poliovirus.

Risk Assessment Reduces Length of Hospital Stay, Costs in Patients who Inject Drugs

Risk Assessment Reduces Length of Hospital Stay, Costs in Patients who Inject Drugs

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A 9-point risk assessment (IVAT) identified persons with a history of injection drug use (IDU) safe for discharge and reduced the mean length of hospital stay (ALOS) by 20 days and total direct cost by 33%.

HPV Vaccination Decreases High-Grade Cervical Lesions in Women

HPV Vaccination Decreases High-Grade Cervical Lesions in Women

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From 2008 to 2015, both cervical intraepithelial neoplasia grades 2, 3 and adenocarcinoma in situ rates and cervical cancer screening declined in women age 18 to 24 years.

Corticosteroid Use May Modestly Reduce Mortality Risk in Sepsis

Corticosteroid Use May Modestly Reduce Mortality Risk in Sepsis

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The use of corticosteroids in sepsis appears to modestly reduce the risk for death and modestly increase neuromuscular weakness but the evidence is not definitive.

High Population Immunity Aids in Global Elimination of Sabin-2 Poliovirus

High Population Immunity Aids in Global Elimination of Sabin-2 Poliovirus

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High population immunity is an indicator of the decline in serotype 2 Sabin vaccine poliovirus after serotype 2 oral poliovirus vaccine withdrawal.

CDC: Some Sexual Minorities Have Higher Sexual Risk Behaviors

CDC: Some Sexual Minorities Have Higher Sexual Risk Behaviors

Bisexual females, 'not sure' males have higher prevalence of many sexual risk behaviors

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