Prevention

New Hope For Immunity Against Polio: An Effective, Reduced-Dose Vaccine

New Hope For Immunity Against Polio: An Effective, Reduced-Dose Vaccine

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Three new aluminum hydroxide adjuvanted, reduced-dose, inactivated polio vaccines (IPV-Al) were found to be noninferior to standard IPV in healthy infants age 6 weeks.

Reducing Unnecessary Antibiotic Use With Rapid Viral Testing

Reducing Unnecessary Antibiotic Use With Rapid Viral Testing

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Patients with acute respiratory illnesses receiving rapid point-of-care testing had a higher dose of antibiotics.

Oral HPV Risk Substantially Reduced With HPV Vaccine

Oral HPV Risk Substantially Reduced With HPV Vaccine

The human papillomavirus (HPV) vaccine offers a higher degree of protection in oral HPV infections.

Boosting Vaccination Rates Among the Elderly

Boosting Vaccination Rates Among the Elderly

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A survey presented at the American Academy of Physician Assistants says a healthcare providers vaccination recommendation for elderly patients is greater than media influence.

Oral Prophylactic Therapy Designated Breakthrough Therapy for CDI Prevention

Oral Prophylactic Therapy Designated Breakthrough Therapy for CDI Prevention

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The FDA granted Breakthrough Therapy designation to Synthetic Biologics' ribaxamase SYN-004 for Clostridium difficile infection prevention.

Low MMR Vaccination Rates in US Adult Travelers

Low MMR Vaccination Rates in US Adult Travelers

More than half of eligible traveling Americans don't get the measles, mumps, rubella vaccine.

PrEP in the Transgender Population: New Study to Examine Effects

PrEP in the Transgender Population: New Study to Examine Effects

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Dr Sara Gianella talks with Dr Sheldon Morris, from the University of California San Diego AntiViral Research Center about an upcoming PrEP study in transgender people, including understanding HIV prevention in this population, uptake of PrEP, and adherence to treatment.

Cholera Vaccine Recommendations Issued by ACIP

Cholera Vaccine Recommendations Issued by ACIP

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Report provides new recommendations and guidance for vaccination providers and travelers about the use of lyophilized CVD 103-HgR (Vaxchora, PaxVax, Redwood City, California).

Pediatric Influenza Armamentarium Bolstered by New Investigational Vaccine

Pediatric Influenza Armamentarium Bolstered by New Investigational Vaccine

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Seqirus IIV4, an investigational quadrivalent inactivated influenza vaccine, was found to be noninferior to US-licensed comparator IIV4 in children aged 5 to 17 years.

Lyme and Other Tickborne Diseases: Tips for Prevention

Lyme and Other Tickborne Diseases: Tips for Prevention

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The US Centers for Disease Control and Prevention released a toolkit to help individuals protect themselves from Lyme and other tickborne diseases.

Periodontal Disease and Rheumatoid Arthritis: What Are the Links?

Periodontal Disease and Rheumatoid Arthritis: What Are the Links?

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Bi-directional mechanisms linking periodontal disease to the development of rheumatoid arthritis may offer biomarkers for the development of RA and treatment objectives that influence the courses of both inflammatory conditions.

CDC: Ensuring a Continuous Yellow Fever Vaccine Supply in US

CDC: Ensuring a Continuous Yellow Fever Vaccine Supply in US

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Sanofi Pasteur submitted an investigational new drug application to the Food and Drug Administration of an alternative to the yellow fever vaccine, Stamaril, after recent shortages of YF-VAX.

EHR and Reporting Tools May Reduce Hospital-acquired Conditions

EHR and Reporting Tools May Reduce Hospital-acquired Conditions

The use of electronic health record (EHR) documentation has helped lower hospital-acquired conditions for inpatients.

Tdap Vaccine More Effective in Second Trimester of Pregnancy

Tdap Vaccine More Effective in Second Trimester of Pregnancy

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Maternal vaccination of tetanus-diphtheria-acellular pertussis (Tdap) was found to be more effective in the second rather than the third trimester of pregnancy.

AAFP Hoping to Boost Adult Vaccination Rates With Educational Videos

AAFP Hoping to Boost Adult Vaccination Rates With Educational Videos

The American Academy of Family Physicians created 3 online videos to educate vaccine-hesitant, adult patients on the benefits of vaccination.

Pneumonia Rate in Children Decreased With PCV10 Vaccine

Pneumonia Rate in Children Decreased With PCV10 Vaccine

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The rate of pneumonia decreased with the introduction of the 10-valent pneumococcal conjugate vaccine (PCV10) in vaccine-eligible children and older, unvaccinated children.

Adolescent HPV Vaccination Rates Improve With Parental Self-Persuasion

Adolescent HPV Vaccination Rates Improve With Parental Self-Persuasion

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Self-persuasion method facilitates HPV vaccination better than external persuasion in low literacy, safety-net settings.

New Guideline on HPV Vaccine for Cervical Cancer Prevention

New Guideline on HPV Vaccine for Cervical Cancer Prevention

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The American Society of Clinical Oncology issued new recommendations based on 4 levels of resource settings on human papillomavirus vaccination for cervical cancer prevention.

Quadrivalent HPV Vaccine Safe During Pregnancy

Quadrivalent HPV Vaccine Safe During Pregnancy

Exposure to the quadrivalent human papillomavirus vaccine during pregnancy shows no increased risk of major adverse pregnancy outcomes.

Tetravalent <i>E coli</i> Vaccine Safe, Immunogenic in Women With Recurrent UTI

Tetravalent E coli Vaccine Safe, Immunogenic in Women With Recurrent UTI

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Phase 1b trial finds tetravalent E coli bioconjugate vaccine candidate in women with recurrent UTI safe and immunogenic.

Review of <i>Clostridium difficile</i> Vaccines in Development

Review of Clostridium difficile Vaccines in Development

Drs Kociolek and Shulman, from the division of infectious diseases at the Ann & Robert H. Lurie Children's Hospital of Chicago in Illinois, review all the current vaccine candidates in development for Clostridium difficile infection.

Influenza Vaccine Safe During Any Trimester of Pregnancy

Influenza Vaccine Safe During Any Trimester of Pregnancy

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Researchers found that the influenza vaccine, when given to pregnant women, does not affect weeks' gestation of the infant at birth or the infant's birth weight.

FDA: QDIP Status for Post-Surgical Sternal Infection Antibiotic Reservoir

FDA: QDIP Status for Post-Surgical Sternal Infection Antibiotic Reservoir

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The FDA has granted Qualified Infectious Disease Product (QIDP) to D-PLEX (Doxycycline/Polymer-Lipid Encapsulation Matrix; PolyPid), a secured antibiotic drug reservoir for the local prevention and treatment of surgical infections.

Reducing Antibiotic Use in Infants With Use of Sepsis Risk Calculator

Reducing Antibiotic Use in Infants With Use of Sepsis Risk Calculator

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A study finds the use of early-onset sepsis calculator can decrease the number of infants receiving a sepsis work-up and prophylactic antibiotics.

Patients' Expectations for Antibiotics Encourage Overprescribing

Patients' Expectations for Antibiotics Encourage Overprescribing

Study finds physicians overprescribe antibiotics to accommodate patient expectations.

Plague Vaccine Granted Orphan Drug Designation

Plague Vaccine Granted Orphan Drug Designation

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FDA has granted Orphan Drug designation to the recombinant rF1V plague vaccine for pre-exposure prophylaxis of Yersinia pestis infection, also known as, the plague.

Immunity Persists for Ebola Vaccines at One Year

Immunity Persists for Ebola Vaccines at One Year

A strategy of preemptive use of an AD26.ZEBOV followed by MVA-BN-Filo immunization schedule in at-risk populations may offer advantages over reactive use of single-dose vaccine regimens.

Reducing CVD Risk Using a Vaccine-Based Approach

Reducing CVD Risk Using a Vaccine-Based Approach

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In preclinical animal studies, vaccination against PSCK9 lowered serum lipids and vaccination against ApoC3 lowered serum triglyceride levels.

Is CMV a Major Contributor to Cardiovascular Disease in RA?

Is CMV a Major Contributor to Cardiovascular Disease in RA?

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An expert Q&A with Florian Kern, PhD, deputy director of research at Brighton and Sussex Medical School in the UK, who makes the case that cytomegalovirus is a major driver of cardiovascular disease in patients with rheumatoid arthritis.

Lower Use of STD Services in Young Adults Due to Confidentiality Issues

Lower Use of STD Services in Young Adults Due to Confidentiality Issues

Sexually active teens reported to not to seek out STD services due to confidentiality issues.

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