Respiratory

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Challenges in Diagnosing Tuberculous Meningitis

Challenges in Diagnosing Tuberculous Meningitis

Diagnosis of tuberculous meningitis is challenging, although new, next-generation rapid POC testing holds promise for greatly improved sensitivity. Shorter and more effective treatments are needed.

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Likelihood of Self-Administered Treatment Completion for Latent TB

Likelihood of Self-Administered Treatment Completion for Latent TB

The iAdhere study found that once-weekly self-administration of isoniazid and rifapentine had high treatment completion rates in the United States, Hong Kong, Spain, and South Africa.

Drug-Resistant Tuberculosis to Increase in 4 High-Burden Countries

Drug-Resistant Tuberculosis to Increase in 4 High-Burden Countries

Additional strategies to prevent transmission will be necessary to stop multidrug-resistant (MDR) or extensively drug-resistant tuberculosis in countries with a high burden of MDR tuberculosis.

Preterm Infants at Higher Risk for RSV Hospitalization Following 2014 Guidance

Preterm Infants at Higher Risk for RSV Hospitalization Following 2014 Guidance

New data shows a higher risk of respiratory syncytial virus hospitalization for preterm infants during the 2015-2016 season vs data from the previous season.

Metformin Reduces Mortality During Tuberculosis Therapy

Metformin Reduces Mortality During Tuberculosis Therapy

Researchers assess all-cause mortality during tuberculosis treatment in patients with diabetes, the use of metformin, and effect sputum culture-conversion rates.

Risk for TB Infection Predicted by New Scoring System

Risk for TB Infection Predicted by New Scoring System

This new risk score may guide the identification of high-risk people who would benefit from preventative measures.

Labored Breathing, Hypoxemia May Indicate Pneumonia in Children

Labored Breathing, Hypoxemia May Indicate Pneumonia in Children

Difficulty breathing and hypoxemia may be a better indication of pneumonia in children.

High-Dose Vitamin D Does Not Prevent Pediatric Viral Upper Respiratory Tract Infections

High-Dose Vitamin D Does Not Prevent Pediatric Viral Upper Respiratory Tract Infections

High-dose vitamin D supplements do not prevent viral upper respiratory tract infections in young children.

Microbiome Diversity in Respiratory Tract Linked to Airway Inflammation

Microbiome Diversity in Respiratory Tract Linked to Airway Inflammation

Lower microbial diversity in the respiratory tract was linked with prophylactic antibiotic use and less airway inflammation in cystic fibrosis.

Respiratory Syncytial Virus Treatment Development Discontinued

Respiratory Syncytial Virus Treatment Development Discontinued

Regeneron discontinued further development of suptavumab for respiratory syncytial virus.

Time to Sputum Culture Conversion Similar in Isoniazid-Resistant and Susceptible TB

Time to Sputum Culture Conversion Similar in Isoniazid-Resistant and Susceptible TB

A new study examined whether isoniazid resistance was associated with variations in treatment outcomes in patients receiving standard first-line pharmacotherapy for TB.

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