Sepsis

Increased Long-Term Seizure Risk Found in Survivors of Sepsis

Increased Long-Term Seizure Risk Found in Survivors of Sepsis

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Patients with sepsis have a greater long-term risk for seizures.

Factors Associated With Lower Risk for Early-Onset Sepsis in Premature Infants

Factors Associated With Lower Risk for Early-Onset Sepsis in Premature Infants

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Identification of premature infants at low risk of early onset sepsis may help guide decisions for initiating and/or discontinuing empirical antibiotic treatments in the first days of life.

Factors Associated With Thrombocytopenia in Neonatal Sepsis

Factors Associated With Thrombocytopenia in Neonatal Sepsis

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Maternal hypertension, intravascular thrombosis, and Gram-negative sepsis were independent risk factors for thrombocytopenia in multivariate analysis.

Using Protein and Biomarkers to Improve Risk Stratification in Sepsis

Using Protein and Biomarkers to Improve Risk Stratification in Sepsis

Addition of previously unconsidered genes from the PERSEVERE model can improve mortality risk stratification for children with septic shock.

Claims-Based Estimates Not Accurate for Sepsis Analysis

Claims-Based Estimates Not Accurate for Sepsis Analysis

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The study includes a large number of diverse hospitals which account for approximately 10% of all acute care hospitalizations in the United States in 2014.

Diagnostic Practices for Sepsis Identification in Febrile Infants

Diagnostic Practices for Sepsis Identification in Febrile Infants

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Infantile sepsis evaluations vary considerably and could benefit from the development of an updated, standardized guideline.

Outcomes of Adolescent Sepsis Cases in Community Hospital ED

Outcomes of Adolescent Sepsis Cases in Community Hospital ED

Sepsis cases among adolescents seen in emergency departments is rare according to a recently published research letter.

Increased CVD Risk Persists for Years After Treatment for Sepsis or Pneumonia

Increased CVD Risk Persists for Years After Treatment for Sepsis or Pneumonia

Cardiovascular disease risks persist for years after sepsis or pneumonia.

Risk of Cardiovascular Disease in Men With Sepsis, Pneumonia

Risk of Cardiovascular Disease in Men With Sepsis, Pneumonia

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Men who have sepsis or pneumonia have a higher risk of cardiovascular disease.

Clinical Update: Community-Acquired Pneumonia Following Sepsis

Clinical Update: Community-Acquired Pneumonia Following Sepsis

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The quick Sepsis-Related Organ Failure Assessment (qSOFA) clinical tool was superior to SIRS criteria for the evaluation of in-hospital mortality.

WHO Passes Resolution to Mark Sepsis as a Global Health Priority

WHO Passes Resolution to Mark Sepsis as a Global Health Priority

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A resolution recently adopted by the World Health Organization's World Health Assembly could significantly lower the incidence and impact of sepsis.

New Scoring System Predicts In-Hospital Mortality in Critically Ill Children With Sepsis

New Scoring System Predicts In-Hospital Mortality in Critically Ill Children With Sepsis

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A new organ dysfunction scoring system that predicts in-hospital mortality was validated in critically ill children admitted to the pediatric intensive care unit.

Follow-up Blood Culture in Gram-Negative Bacteremia Should Be Avoided

Follow-up Blood Culture in Gram-Negative Bacteremia Should Be Avoided

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Follow-up blood cultures may have little utility in the management of Gram-negative bacilli bacteremia, according to data from a recent study.

Septic Arthritis Outbreak in NJ Linked to Intra-articular Injections

Septic Arthritis Outbreak in NJ Linked to Intra-articular Injections

An outbreak of septic arthritis linked to intra-articular injections was identified at an outpatient practice in New Jersey.

Reduced Incidence of Sepsis in Patients With Asthma

Reduced Incidence of Sepsis in Patients With Asthma

Asthma patients with infections have a reduced risk of developing sepsis.

Sepsis-Related Mortality Decreased With Rapid Implementation of Protocol

Sepsis-Related Mortality Decreased With Rapid Implementation of Protocol

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Rapid treatment of sepsis using mandated care bundles improves outcomes.

Case of <i>Vibrio vulnificus</i> Septic Shock Leading to Death After New Tattoo

Case of Vibrio vulnificus Septic Shock Leading to Death After New Tattoo

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A patient who recently acquired a new tattoo developed Vibrio vulnificus septic shock after swimming in seawater, leading to death.

Preadmission Corticosteroids Lower ARDS Risk in Patients With Sepsis

Preadmission Corticosteroids Lower ARDS Risk in Patients With Sepsis

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Retrospective study analyzes whether preadmission oral corticosteroids might lower ARDS risk in patients admitted to the ICU.

Does Sepsis Risk Increase With Short-term Oral Corticosteroid Use?

Does Sepsis Risk Increase With Short-term Oral Corticosteroid Use?

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An increased risk in sepsis was linked to short-term oral corticosteroid use.

Sepsis May Increase Risk of Long-Term Seizures

Sepsis May Increase Risk of Long-Term Seizures

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Sepsis is associated with pathways that lead to permanent neurological sequelae, according to research presented at the 2017 AAN annual meeting.

Does Early Goal-Directed Therapy Reduce Mortality in Septic Shock?

Does Early Goal-Directed Therapy Reduce Mortality in Septic Shock?

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Three multicenter trials (ProCESS, ARISE, and ProMISe) showed that EGDT did not reduce mortality in patients presenting to the emergency department with septic shock when compared to usual care.

Shortage of Norepinephrine Linked to Increase in Septic Shock Deaths

Shortage of Norepinephrine Linked to Increase in Septic Shock Deaths

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Hospitals see higher rate of in-hospital mortality from septic shock after norepinephrine shortage.

Reducing Antibiotic Use in Infants With Use of Sepsis Risk Calculator

Reducing Antibiotic Use in Infants With Use of Sepsis Risk Calculator

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A study finds the use of early-onset sepsis calculator can decrease the number of infants receiving a sepsis work-up and prophylactic antibiotics.

Considerable Variation Seen in Risk Assessment for Sepsis in Newborns

Considerable Variation Seen in Risk Assessment for Sepsis in Newborns

The most common factor used to identify risk for early onset sepsis was obstetric diagnosis of chorioamnionitis, according to the study.

FDA Approves Procalcitonin Biomarker Test to Aid Antibiotic Decision Making

FDA Approves Procalcitonin Biomarker Test to Aid Antibiotic Decision Making

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Test uses procalcitonin as a biomarker to help make antibiotic management decisions in patients with lower respiratory tract infections and sepsis.

SOFA Score Better Predicts In-Hospital Mortality for Adults in ICU

SOFA Score Better Predicts In-Hospital Mortality for Adults in ICU

SOFA score has greater prognostic accuracy for in-hospital mortality than SIRS criteria or the qSOFA score.

No Effect of Alkalosis on Mortality in ICU Patients With Sepsis

No Effect of Alkalosis on Mortality in ICU Patients With Sepsis

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Metabolic alkalosis did not have any effect on 30-day and 12-month mortality in patients with severe sepsis or septic shock.

Quick SOFA Better Than SIRS, Severe Sepsis in Identifying Mortality Risk

Quick SOFA Better Than SIRS, Severe Sepsis in Identifying Mortality Risk

Quick SOFA had greater prognostic accuracy for in-hospital mortality than did either SIRS or severe sepsis.

Sepsis and Septic Shock: Updated Management Guidelines

Sepsis and Septic Shock: Updated Management Guidelines

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Researchers have updated the 2012 sepsis and septic shock management guidelines based on the results of recent clinical trials.

Presepsin Accurately Detects Early-Onset Sepsis in Preterm Neonates

Presepsin Accurately Detects Early-Onset Sepsis in Preterm Neonates

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Compared with pro-calcitonin and C-reactive protein, presepsin has better diagnostic accuracy in discriminating early-onset sepsis.

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