The journal Annals of Emergency Medicine recently published an article reviewing the tools used to diagnose necrotizing soft tissue infection.
After cesarean delivery, the incision site harbors a higher bacterial biomass in obese women than in non-obese women.
The Committee's recommendation was based on data from the omadacycline global development program that included nearly 2000 adults in three Phase 3 studies.
Staphylococcal scalded skin syndrome is associated with substantial patient morbidity and costs.
The NDA includes safety and efficacy data from two Phase 3 trials (REVIVE-1 and REVIVE-2; N=1190) which compared intravenous iclaprim to standard-of-care vancomycin in patients with ABSSSI.
Researchers assessed the incidence of Cutibacterium avidum infection in patients following primary hip arthroplasty.
Deployment-related trauma infectious complications continue after initial hospital discharge and into Veterans Affairs healthcare.
The morphology of the lesions included erythematous papules, pseudovesicles, and plaques, with associated pain in 2 and pruritus in 3 patients; systemic symptoms ranged from none to low‐grade fevers, upper respiratory symptoms, and joint pain.
Omadacycline met all required FDA and European Medicines Agency primary endpoints in each study and demonstrated a generally safe and well-tolerated profile.
Researchers reviewed clinical trial data to evaluate the efficacy of herpes zoster subunit vaccine in preventing complications, hospitalizations, and deaths.
GBS infections in infants, cellulitis and necrotizing fasciitis, although uncommon in infants, requires swift treatment with antibiotics and occasionally surgical debridement.
Trimethoprim and sulfamethoxazole or clindamycin confer a modest benefit for several important outcomes, but this is offset by a similar risk for adverse effects.
Low-dose azithromycin did not meet the prespecified noninferiority margin compared with standard-dose azithromycin in achieving clinical and serological cure in PCR-confirmed active yaws.
Strains of Staphylococcus epidermidis producing 6-N-hydroxyaminopurine (6-HAP) may provide protection against skin cancer.
Organ systems where bacterial infections predominate as well as fungal diseases were associated with substantial increases in magnitude among patients with both T1D and T2D, but risks were consistently higher for T1D.
The Advisory Committee on Immunization Practices has provided 3 new recommendations to supplement its original 2008 report, as well as a cost-effectiveness analysis from the CDC.
Melinta Therapeutics announced the availability of oral and intravenous forms of Baxdela (delafloxacin) for the treatment of adults with ABSSSI.
A case of remission of psoriasis after treatment of chronic hepatitis C virus has been described.
Iclaprim was noninferior to vancomycin with respect to the early clinical response at an early time point in the treatment of ABSSSI caused or suspected to be caused by gram-positive organisms.
Long-term oral macrolide administration may increase macrolide-resistant Propionibacterium acnes.
Clofazimine was safe and well-tolerated as part of a multidrug regimen for the treatment of children with Mycobacterium abscessus odontogenic infections.
Risk of herpes zoster (HZ) is not significantly increased for systemically treated patients or for those receiving biologics vs nonbiologics in psoriasis.
Atopic dermatitis disease severity is associated with IgG responses against Staphylococcus aureus antigens.
Trimethoprim-sulfamethoxazole appears to improve cure rates after incision and drainage of MRSA abscesses regardless of patient characteristics.
A test-and-not-treat strategy may help areas in which loiasis is endemic and onchocerciasis is hypoendemic so that individuals who are not at risk for serious adverse events are safely given ivermectin treatment.
Penicillin allergy may compromise receipt of recommended antibiotic prophylaxis intended to prevent surgical site infections.
Clinical factors such as severity of infection on presentation and underlying comorbidities were the main factors influencing treatment decisions.
Dalbavancin is an effective and well-tolerated treatment for ABSSSI, including in patients who met SIRS criteria.
Compared with vancomycin, patients with ABSSSI treated with ceftaroline fosamil had significantly shorter length of hospital stay.
Omadacycline was non-inferior to moxifloxacin for treatment of CABP and linezolid for treatment of ABSSSI.
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