Skin Infections

Safety of Clofazimine in Treating Children With <i>Mycobacterium abscessus</i> Infections

Safety of Clofazimine in Treating Children With Mycobacterium abscessus Infections

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Clofazimine was safe and well-tolerated as part of a multidrug regimen for the treatment of children with Mycobacterium abscessus odontogenic infections.

No Difference in Herpes Zoster Risk With Biologic- vs Nonbiologic-Treated Psoriasis

No Difference in Herpes Zoster Risk With Biologic- vs Nonbiologic-Treated Psoriasis

Risk of herpes zoster (HZ) is not significantly increased for systemically treated patients or for those receiving biologics vs nonbiologics in psoriasis.

IgG Response to <i>S aureus</i> Linked to Severe Atopic Dermatitis in Children

IgG Response to S aureus Linked to Severe Atopic Dermatitis in Children

Atopic dermatitis disease severity is associated with IgG responses against Staphylococcus aureus antigens.

Trimethoprim-Sulfamethoxazole Effective Regardless of Abscess Size

Trimethoprim-Sulfamethoxazole Effective Regardless of Abscess Size

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Trimethoprim-sulfamethoxazole appears to improve cure rates after incision and drainage of MRSA abscesses regardless of patient characteristics.

Rapid, Point-of-Care Tool for Identifying Onchocerciasis in <i>L loa</i>-Endemic Areas

Rapid, Point-of-Care Tool for Identifying Onchocerciasis in L loa-Endemic Areas

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A test-and-not-treat strategy may help areas in which loiasis is endemic and onchocerciasis is hypoendemic so that individuals who are not at risk for serious adverse events are safely given ivermectin treatment.

Reported Penicillin Allergy Increases Risk of Surgical Site Infections

Reported Penicillin Allergy Increases Risk of Surgical Site Infections

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Penicillin allergy may compromise receipt of recommended antibiotic prophylaxis intended to prevent surgical site infections.

Frequent Emergency Medicine Decision-Making Factors in ABSSSI Treatment

Frequent Emergency Medicine Decision-Making Factors in ABSSSI Treatment

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Clinical factors such as severity of infection on presentation and underlying comorbidities were the main factors influencing treatment decisions.

Dalbavancin Safe and Effective for ABSSSI in Patients With SIRS

Dalbavancin Safe and Effective for ABSSSI in Patients With SIRS

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Dalbavancin is an effective and well-tolerated treatment for ABSSSI, including in patients who met SIRS criteria.

Ceftaroline Fosamil Associated With Shorter ABSSSI-Related Hospital Stay

Ceftaroline Fosamil Associated With Shorter ABSSSI-Related Hospital Stay

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Compared with vancomycin, patients with ABSSSI treated with ceftaroline fosamil had significantly shorter length of hospital stay.

Effect of Omadacycline on Cardiac Parameters in ABSSSI and CABP

Effect of Omadacycline on Cardiac Parameters in ABSSSI and CABP

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Omadacycline was non-inferior to moxifloxacin for treatment of CABP and linezolid for treatment of ABSSSI.

Omadacycline Noninferior to Linezolid in ABSSSI Patients With High BMI, Diabetes

Omadacycline Noninferior to Linezolid in ABSSSI Patients With High BMI, Diabetes

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The goal of this post-hoc analysis of OASIS-1 study was to determine if BMI or T2D had any effect on the efficacy or safety of omadacycline relative to linezolid.

Intramuscular Benzathine Penicillin Reduced Incidence of Recurrent Cellulitis

Intramuscular Benzathine Penicillin Reduced Incidence of Recurrent Cellulitis

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Although intramuscular antibiotics had been suggested as a prevention strategy for recurrent cellulitis, the evidence is scarce.

Treating ABSSSI in Diabetes: Efficacy of Dalbavancin Examined

Treating ABSSSI in Diabetes: Efficacy of Dalbavancin Examined

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Dalbavancin has shown potent activity against gram-positive pathogens responsible for ABSSSI, including MRSA.

Fournier's Gangrene: Incidence, Risk Factors, and Adverse Outcomes

Fournier's Gangrene: Incidence, Risk Factors, and Adverse Outcomes

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Study suggests a higher incidence of Fournier's gangrene than previously described.

Cost Effectiveness of Dalbavancin, Oritavancin in Acute Skin Infections

Cost Effectiveness of Dalbavancin, Oritavancin in Acute Skin Infections

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Dalbavancin and oritavancin may make it possible to allow for earlier discharge and reduce health care costs without compromising efficacy.

Weight-Based Dosing of Clindamycin and TMP/SMX Improves Cellulitis Outcomes

Weight-Based Dosing of Clindamycin and TMP/SMX Improves Cellulitis Outcomes

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Weight-based dosing options for treatment may improve clinical outcomes in patients with cellulitis.

Rapid Decrease in Lesion Size and Pain With Delafloxacin in ABSSSI

Rapid Decrease in Lesion Size and Pain With Delafloxacin in ABSSSI

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Delafloxacin is comparable to vancomycin/aztreonam in the reduction of the signs and symptoms of ABSSSI.

Dalbavancin Safe, Efficacious for Skin Infections Regardless of Weight

Dalbavancin Safe, Efficacious for Skin Infections Regardless of Weight

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Subanalysis of a previously published randomized double-blind phase 3 trial in patients with ABSSSI found that dalbavancin was well-tolerated in obese patients.

Respiratory Infections, Repeat Surgeries Up SSI Risk in Total Joint Arthroplasty

Respiratory Infections, Repeat Surgeries Up SSI Risk in Total Joint Arthroplasty

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Total knee arthroplasty is more commonly linked to surgical site infection compared to total hip arthroplasty.

Skin Diseases Remain Common in Older Adults With HIV

Skin Diseases Remain Common in Older Adults With HIV

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Cutaneous manifestations are frequently associated with immune dysfunction in HIV.

Intravenous Ertapenem May Control Hidradenitis Suppurativa Symptoms

Intravenous Ertapenem May Control Hidradenitis Suppurativa Symptoms

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No durable control of Hidradenitis Suppurativa is seen with current management strategies including topical and/or oral antibiotics, immunomodulatory drugs, and local surgery.

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