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FDA Approves New Treatment for Onchocerciasis

FDA Approves New Treatment for Onchocerciasis

Moxidectin, a macrocyclic lactone, is an anthelmintic drug that selectively binds to the parasite's glutamate-gated chloride ion channels.

FDA Grant Orphan Drug Status to Brincidofovir for Smallpox

FDA Grant Orphan Drug Status to Brincidofovir for Smallpox

Brincidofovir is the Company's lead candidate, a nucleotide analog that has antiviral activity against variola virus, which causes smallpox.

Treatment for Prosthetic Joint Infections Gets FDA's QIDP Designation

Treatment for Prosthetic Joint Infections Gets FDA's QIDP Designation

PJI is a challenging complication of joint arthroplasty with few effective treatment options.

Children Typically Have 14 Simple Infections by Age 3 Years

Children Typically Have 14 Simple Infections by Age 3 Years

Children experience a median of 14 infections during their first three years of life, though there is large variation in incidence.

First Single-Dose Oral Therapy for Bacterial Vaginosis Launched

First Single-Dose Oral Therapy for Bacterial Vaginosis Launched

In both pivotal trials, a statistically significant greater percentage of treatment patients experienced clinical response vs those treated with placebo at 21 to 30 days following a single dose.

Infection Risk With Second-Generation Disease-Modifying Treatments in MS

Infection Risk With Second-Generation Disease-Modifying Treatments in MS

Investigators examined the association between infection-related medical encounters and disease-modifying treatments for multiple sclerosis.

FDA Panel Votes on Plazomicin for Complicated UTI, Bloodstream Infections

FDA Panel Votes on Plazomicin for Complicated UTI, Bloodstream Infections

The Committee voted unanimously (15-0) that substantial evidence on the safety and efficacy of plazomicin was presented for the treatment of cUTI but voted against its use (4-11) for the treatment of bloodstream infections in patients with limited or no treatment options.

Novel Drug Combinations, Dosing Strategies Needed for E faecalis Bloodstream Infections

Novel Drug Combinations, Dosing Strategies Needed for E faecalis Bloodstream Infections

Review highlights available treatment options and their limitations and provides direction for investigation of future novel combination therapies to further aid in the treatment of Enterococcus faecalis infective endocarditis.

Antiherpetic Medications May Reduce Risk for Dementia

Antiherpetic Medications May Reduce Risk for Dementia

Patients with herpes simplex virus infections may have a 2.56-fold increased risk for developing dementia, and using antiherpetic medications may decrease dementia risk.

Colistin Plus Meropenem Not Superior to Monotherapy for Carbapenem-Resistant Gram-Negative Bacteria

Colistin Plus Meropenem Not Superior to Monotherapy for Carbapenem-Resistant Gram-Negative Bacteria

Results strongly support the avoidance of colistin-carbapenem combination therapy for carbapenem-resistant A baumannii infections regardless of the infection source.

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