Treatments

Biotherapeutics for the Prevention of <i>Clostridium difficile</i> Infection

Biotherapeutics for the Prevention of Clostridium difficile Infection

Experts review biotherapeutics for the prevention of C difficile infection, including probiotics, fecal microbiota transplantation, and nontoxigenic C difficile.

Improving QoL in Patients With Bronchiectasis and <i>Pseudomonas aeruginosa</i>

Improving QoL in Patients With Bronchiectasis and Pseudomonas aeruginosa

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High-doses of atorvastatin reduced inflammation and improved health-related quality of life in patients with bronchiectasis.

Efficacy of Bismuth-Based Quad Tx vs Levofloxacin Triple Tx for <i>H pylori</i>

Efficacy of Bismuth-Based Quad Tx vs Levofloxacin Triple Tx for H pylori

The addition of bismuth subcitrate to levofloxacin-based triple therapy is not associated with increased effectiveness in patients with Helicobacter pylori infection.

Novel Oral Antifungal Drug for Valley Fever Gets Fast Track Designation

Novel Oral Antifungal Drug for Valley Fever Gets Fast Track Designation

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The FDA has given Fast Track designation to an oral drug candidate for treating Valley Fever.

CMV Infection in Mothers and Infants: Diagnostic and Treatment Challenges

CMV Infection in Mothers and Infants: Diagnostic and Treatment Challenges

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Cytomeglovirus infection is associated with a range of diagnostic and treatment challenges and a relatively high transmission rate from the mother to the fetus.

Mortality in MDR TB Decreases With Directly Observed Therapy

Mortality in MDR TB Decreases With Directly Observed Therapy

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A decrease in all-cause mortality associated with multidrug-resistant tuberculosis (TB) can be correlated with an increase in directly observed therapy.

Meningococcal Disease Risk Linked to Eculizumab Despite Vaccination

Meningococcal Disease Risk Linked to Eculizumab Despite Vaccination

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Meningococcal disease risk has been linked to eculizumab despite previous vaccination.

No Benefits Seen for Adjunctive Clindamycin in Cellulitis

No Benefits Seen for Adjunctive Clindamycin in Cellulitis

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Results from atrial of clindamycin in cellulitis cast doubt on hospital guidelines.

Antimicrobial Dressing For Diabetic Foot Ulcers Improve Healing

Antimicrobial Dressing For Diabetic Foot Ulcers Improve Healing

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Using antimicrobial dressing instead of a non-antimicrobial dressing may increase healing of diabetic foot ulcers.

Amphotericin B Better Than Itraconazole in HIV-Linked Talaromycosis

Amphotericin B Better Than Itraconazole in HIV-Linked Talaromycosis

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Treatment with antifungal drug amphotericin B is superior to itraconazole for HIV-associated talaromycosis.

Herpes Zoster Risk May Increase With Common Rheumatoid Arthritis Drugs

Herpes Zoster Risk May Increase With Common Rheumatoid Arthritis Drugs

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Common rheumatoid arthritis drugs methotrexate and biologics may increase risk for herpes zoster.

New Penicillin G Dosing Schedule Improves Treatment for Erysipelas

New Penicillin G Dosing Schedule Improves Treatment for Erysipelas

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Frequent recurrence of erysipelas has been a major challenge to treatment. Investigators looked at adjustments to the dosing schedule to improve efficacy of an existing therapy.

Sepsis-Related Mortality Decreased With Rapid Implementation of Protocol

Sepsis-Related Mortality Decreased With Rapid Implementation of Protocol

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Rapid treatment of sepsis using mandated care bundles improves outcomes.

Treatments for Chronic Lyme Disease Can Carry Serious Risks

Treatments for Chronic Lyme Disease Can Carry Serious Risks

Serious bacterial infections have been documented during Lyme Disease treatment in some patients.

New Assay Targets Susceptibility to Ciprofloxacin in Gonorrhea

New Assay Targets Susceptibility to Ciprofloxacin in Gonorrhea

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In an effort to combat extensive drug-resistance in gonorrhea, a new assay identifies patients who may still have a response to an older, less reliable therapy.

Designer Protein Halts Influenza Virus From Infecting Cells

Designer Protein Halts Influenza Virus From Infecting Cells

A designer protein stopped the influenza virus from infecting cells in culture and protected mice after being exposed to heavy doses of the virus, according to a new study.

FDA Approves New Dosing Option for Raltegravir in Treating HIV-1

FDA Approves New Dosing Option for Raltegravir in Treating HIV-1

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The FDA approved higher dose of Isentress for the treatment of HIV-1 infection in adults and pediatric patients.

FDA: New Oral Powder Formulation Approved for HIV Treatment

FDA: New Oral Powder Formulation Approved for HIV Treatment

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Norvir, an oral powder formulation to treat HIV-1 patients, has been approved by the FDA.

Adherence to Antiretroviral Therapy Increased From 2001 to 2010

Adherence to Antiretroviral Therapy Increased From 2001 to 2010

More Americans with HIV are adhering to antiretroviral therapy regimens.

New Drugs Added to the WHO 2017 Essential Medicines List

New Drugs Added to the WHO 2017 Essential Medicines List

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The WHO issued a new list of essential medicines for 2017, adding new treatments for HIV, hepatitis C virus, and tuberculosis.

 High Rate of SVR Across All HCV Genotypes With Three-Drug Combo

High Rate of SVR Across All HCV Genotypes With Three-Drug Combo

A combination pill of sofosbuvir, velpatasvir, and voxilaprevir is nearly 100% effective in curing hepatitis C in patients whose disease returned after treatment with direct-acting antiviral agents.

 Medication Nonadherence May be Due to Side Effects in Chronic Disease

Medication Nonadherence May be Due to Side Effects in Chronic Disease

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Data cited unpleasant side effects as the only statistically significant factor that influenced medication nonadherence in patients with chronic diseases.

Low Rates of Infection, Lymphopenia With Teriflunomide Treatment for MS

Low Rates of Infection, Lymphopenia With Teriflunomide Treatment for MS

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Studies sought to describe the effects of teriflunomide treatment on lymphocyte counts and infection rates in relapsing forms of multiple sclerosis (MS).

Ridinilazole Beats Standard of Care in Phase 2 <i>C difficile</i> Study

Ridinilazole Beats Standard of Care in Phase 2 C difficile Study

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Recurrent Clostridium difficile infection is associated with a significant economic and mortality burden, but new treatment shows promise.

Treating Uncomplicated Cellulitis: Is Adding TMP/SMX Beneficial?

Treating Uncomplicated Cellulitis: Is Adding TMP/SMX Beneficial?

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Adding trimethoprim-sulfamethoxazole to cephalexin treatment for cellulitis does not benefit outcomes compared to cephalexin alone.

HIV RNA Replication in Semen Occurs During Antiretroviral Therapy

HIV RNA Replication in Semen Occurs During Antiretroviral Therapy

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Study looks at the decay of HIV viral load in the genital tract by comparing the effect of different drug families on treatment-naive HIV-infected patients.

Plant Bulbs Found to Carry Triazole-Resistant <i>Aspergillus fumigatus</i>

Plant Bulbs Found to Carry Triazole-Resistant Aspergillus fumigatus

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Researchers find that the spread of triazole-resistant Aspergillus fumigatus is linked to plant bulbs.

Does Sepsis Risk Increase With Short-term Oral Corticosteroid Use?

Does Sepsis Risk Increase With Short-term Oral Corticosteroid Use?

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An increased risk in sepsis was linked to short-term oral corticosteroid use.

Pneumonia Risk Higher in Asthma Patients Using Inhaled Corticosteroid

Pneumonia Risk Higher in Asthma Patients Using Inhaled Corticosteroid

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Use of inhaled corticosteroids is linked to increased risk of pneumonia in patents with asthma.

Efficacy of Antibiotic Regimens Compared for Treating PID

Efficacy of Antibiotic Regimens Compared for Treating PID

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A Cochrane review of antibiotic treatments for pelvic inflammatory disease found no definitive evidence that one treatment was more effective or safer than the other.

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