Vaccines

New Hope For Immunity Against Polio: An Effective, Reduced-Dose Vaccine

New Hope For Immunity Against Polio: An Effective, Reduced-Dose Vaccine

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Three new aluminum hydroxide adjuvanted, reduced-dose, inactivated polio vaccines (IPV-Al) were found to be noninferior to standard IPV in healthy infants age 6 weeks.

Oral HPV Risk Substantially Reduced With HPV Vaccine

Oral HPV Risk Substantially Reduced With HPV Vaccine

The human papillomavirus (HPV) vaccine offers a higher degree of protection in oral HPV infections.

Boosting Vaccination Rates Among the Elderly

Boosting Vaccination Rates Among the Elderly

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A survey presented at the American Academy of Physician Assistants says a healthcare providers vaccination recommendation for elderly patients is greater than media influence.

Low MMR Vaccination Rates in US Adult Travelers

Low MMR Vaccination Rates in US Adult Travelers

More than half of eligible traveling Americans don't get the measles, mumps, rubella vaccine.

Influenza Vaccine Dose-Sparing Possible Without Compromising Safety

Influenza Vaccine Dose-Sparing Possible Without Compromising Safety

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A prospective multicenter study examined the optimal dose of seasonal trivalent influenza vaccines.

Cholera Vaccine Recommendations Issued by ACIP

Cholera Vaccine Recommendations Issued by ACIP

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Report provides new recommendations and guidance for vaccination providers and travelers about the use of lyophilized CVD 103-HgR (Vaxchora, PaxVax, Redwood City, California).

Pediatric Influenza Armamentarium Bolstered by New Investigational Vaccine

Pediatric Influenza Armamentarium Bolstered by New Investigational Vaccine

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Seqirus IIV4, an investigational quadrivalent inactivated influenza vaccine, was found to be noninferior to US-licensed comparator IIV4 in children aged 5 to 17 years.

Higher Risk for Pneumonia in HIV Does Not Mean Worse Outcomes

Higher Risk for Pneumonia in HIV Does Not Mean Worse Outcomes

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A Barcelona study found that patients with HIV required no special treatment for pneumonia compared with healthy individuals.

CDC: Ensuring a Continuous Yellow Fever Vaccine Supply in US

CDC: Ensuring a Continuous Yellow Fever Vaccine Supply in US

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Sanofi Pasteur submitted an investigational new drug application to the Food and Drug Administration of an alternative to the yellow fever vaccine, Stamaril, after recent shortages of YF-VAX.

Pertussis Booster Dose Safe in Pediatric Patients With IBD

Pertussis Booster Dose Safe in Pediatric Patients With IBD

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A booster dose of pertussis vaccine is safe and immunogenic for pediatric patients with inflammatory bowel disease.

Tdap Vaccine More Effective in Second Trimester of Pregnancy

Tdap Vaccine More Effective in Second Trimester of Pregnancy

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Maternal vaccination of tetanus-diphtheria-acellular pertussis (Tdap) was found to be more effective in the second rather than the third trimester of pregnancy.

NIH Begins Phase 2 Zika Vaccine Trials

NIH Begins Phase 2 Zika Vaccine Trials

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The National Institute of Allergy and Infectious Diseases began phase 2/2b of a multisite clinical trial of an investigational vaccine against the Zika virus.

Three Cases of Mumps Complications Investigated

Three Cases of Mumps Complications Investigated

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Patients who received at least 2 doses of the recommended measles-mumps-rubella vaccine still suffered complications during an outbreak at the University of Iowa.

AAFP Hoping to Boost Adult Vaccination Rates With Educational Videos

AAFP Hoping to Boost Adult Vaccination Rates With Educational Videos

The American Academy of Family Physicians created 3 online videos to educate vaccine-hesitant, adult patients on the benefits of vaccination.

Efficacy of H1N1 Influenza Vaccine Much Stronger in Children

Efficacy of H1N1 Influenza Vaccine Much Stronger in Children

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Vaccines used since the 2009 pandemic were found to be effective in the prevention of influenza and influenza-related hospitalization, particularly among children.

FDA Approves Extended Shelf Life for Egg-Free Influenza Vaccine

FDA Approves Extended Shelf Life for Egg-Free Influenza Vaccine

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Flublok Quadrivalent, an influenza vaccine, was approved an extended shelf life of 6 to 9 months by the FDA.

Pneumonia Rate in Children Decreased With PCV10 Vaccine

Pneumonia Rate in Children Decreased With PCV10 Vaccine

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The rate of pneumonia decreased with the introduction of the 10-valent pneumococcal conjugate vaccine (PCV10) in vaccine-eligible children and older, unvaccinated children.

Wide Variation in Flu Vaccination Coverage by Industry and Occupation

Wide Variation in Flu Vaccination Coverage by Industry and Occupation

There was variation in flu vaccination coverage by industry and occupation, with high coverage in the health care industries and occupations.

Vaccination Reduces Influenza-associated Death in Children and Adolescents

Vaccination Reduces Influenza-associated Death in Children and Adolescents

Vaccination reduces influenza-associated death in children with overall effectiveness of 65%.

Maternal Tdap Vaccination Highly Protective Against Infant Pertussis

Maternal Tdap Vaccination Highly Protective Against Infant Pertussis

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Maternal Tdap vaccination was found to be highly protective against pertussis in newborns.

Adolescent HPV Vaccination Rates Improve With Parental Self-Persuasion

Adolescent HPV Vaccination Rates Improve With Parental Self-Persuasion

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Self-persuasion method facilitates HPV vaccination better than external persuasion in low literacy, safety-net settings.

CDC: Nearly Half of US Adults Infected With HPV

CDC: Nearly Half of US Adults Infected With HPV

HPV vaccine has the potential to reverse the epidemic and prevent thousands of cancers in the United States each year.

New Guideline on HPV Vaccine for Cervical Cancer Prevention

New Guideline on HPV Vaccine for Cervical Cancer Prevention

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The American Society of Clinical Oncology issued new recommendations based on 4 levels of resource settings on human papillomavirus vaccination for cervical cancer prevention.

Quadrivalent HPV Vaccine Safe During Pregnancy

Quadrivalent HPV Vaccine Safe During Pregnancy

Exposure to the quadrivalent human papillomavirus vaccine during pregnancy shows no increased risk of major adverse pregnancy outcomes.

Novel Vaccine Improves Shedding and Lesion Rates in HSV-2

Novel Vaccine Improves Shedding and Lesion Rates in HSV-2

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A randomized trial shows that a candidate HSV-2 vaccine had a favorable safety profile and led to reduced shedding and lesion rates in human participants.

Tetravalent <i>E coli</i> Vaccine Safe, Immunogenic in Women With Recurrent UTI

Tetravalent E coli Vaccine Safe, Immunogenic in Women With Recurrent UTI

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Phase 1b trial finds tetravalent E coli bioconjugate vaccine candidate in women with recurrent UTI safe and immunogenic.

Review of <i>Clostridium difficile</i> Vaccines in Development

Review of Clostridium difficile Vaccines in Development

Drs Kociolek and Shulman, from the division of infectious diseases at the Ann & Robert H. Lurie Children's Hospital of Chicago in Illinois, review all the current vaccine candidates in development for Clostridium difficile infection.

Influenza Vaccine Safe During Any Trimester of Pregnancy

Influenza Vaccine Safe During Any Trimester of Pregnancy

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Researchers found that the influenza vaccine, when given to pregnant women, does not affect weeks' gestation of the infant at birth or the infant's birth weight.

Plague Vaccine Granted Orphan Drug Designation

Plague Vaccine Granted Orphan Drug Designation

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FDA has granted Orphan Drug designation to the recombinant rF1V plague vaccine for pre-exposure prophylaxis of Yersinia pestis infection, also known as, the plague.

Immunity Persists for Ebola Vaccines at One Year

Immunity Persists for Ebola Vaccines at One Year

A strategy of preemptive use of an AD26.ZEBOV followed by MVA-BN-Filo immunization schedule in at-risk populations may offer advantages over reactive use of single-dose vaccine regimens.

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