The burden of childhood and infant pneumonia can be effectively reduced through the use of the pneumococcal Haemophilus influenzae protein D conjugate vaccine.
Repeated exposure to the influenza virus affects antibody quantity and quality, and strains selected for seasonal vaccines may not provide coverage sufficient for individuals frequently infected and/or vaccinated.
A high level of population-wide immunity at the time the oral polio vaccine 2 was withdrawn has helped to enhance the disappearance of Sabin-2 vaccine poliovirus.
From 2008 to 2015, both cervical intraepithelial neoplasia grades 2, 3 and adenocarcinoma in situ rates and cervical cancer screening declined in women age 18 to 24 years.
Suppressing cytomegalovirus may improve the immune response to a T cell-dependent pneumococcal vaccination in patients experiencing ANCA-associated vasculitis.
According to the Centers for Disease Control and Prevention (CDC), the 2017-2018 flu season was one of the most severe - excluding pandemics - on record.
Age-specific mortality from subacute sclerosing panencephalitis, the neurodegenerative disease caused by the measles virus, is reflective of changes in measles age distributions, and the condition could disappear in the United States if measles vaccination rates remain high.
Specimens of the rapidly evolving virus are needed to develop vaccines and treatments.
In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.
Prenatal Tdap vaccination is not associated with increased risk of autism spectrum disorder in offspring.
Immunization with Tdap vaccine during pregnancy results in higher levels of antibodies early in infancy but lower levels after the primary vaccine series.
Patients with rheumatoid arthritis, particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality.
The 9-valent HPV vaccine could be a therapeutic option for patients with cutaneous squamous cell carcinoma when surgical management is not an option.
Both LAIV and IIV are safe for nursing mothers, however, breast milk and serum antibody responses were higher for IIV.
In healthy adults, intradermal (ID) administration of a double dose of 0.1 mL (0.1 ID) of human diploid cell culture rabies vaccine over the course of 2 visits was safe and not inferior to the single-dose 3-visit ID schedule.
Early findings show that the P27A candidate vaccine for malaria prevention appeared to be safe and induced a strong immunogenic response with parasite growth inhibitory capacity.
Inverse association identified between NME rate and MMR vaccine coverage of kindergarteners
Adherence and completion to multidose vaccine schedules for hepatitis A, B, and A-B are low, thereby rendering vaccination ineffective.
A new study found no immunologic interference with the co-administration of Shingrix vaccine and the PCV 23 in adult patients
Human Challenge Studies in Infectious Disease: Despite Need for Rigorous Oversight, Studies Are VitalJune 18, 2018
Barriers to challenge studies include ethical guidelines indicating that the generation of scientific knowledge should never supersede the rights and interests of research subjects.
Specifically, the types the vaccine protects against are HPV 16, 18, 31, 33, 45, 52, 58 (which cause ~90% of cervical cancer cases worldwide), and types 6 and 11 which case genital warts.
The CDC recommends 2 doses of the MMR vaccine, which provides 97% protection against measles, prior to international travel.
In a phase 3 clinical trial, early vaccination effectively prevented herpes zoster in auto-HSCT recipients.
At non VA hospitals, but not in VA hospitals, there was an increase in mandatory influenza vaccination requirements for health care personnel from 2013 to 2017.
No new or unexpected safety issues have been identified in association with DTaP vaccines in the US
With the advent of platform manufacturing technology, vaccines can be developed quickly to stop the spread of outbreaks.
Between October 20, 2017 and February 20, 2018, the Vaccine Adverse Event Reporting System (VAERS) received 155 reports involving RZV, with 13 (8%) involving an administrative error.
Others have argued that dismissal is ethically problematic because it can deprive children of comprehensive pediatric care and undermine public health.
Results support further development of NDV-3A vaccine and provide guidance for meaningful clinical endpoints for immunotherapeutic management of recurrent vulvovaginal candidiasis.
The World Health Organization recommends vaccination in cases of confirmed outbreaks of typhoid fever, although data on the use of vaccines in controlling outbreaks are very limited and research to assess the value of vaccination in these cases is strongly recommended.
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Infectious Disease Advisor Articles
- The Misuse of Antibiotics in Acute Pancreatitis Appears Widespread
- ART Reduces Neurocognitive Impairment in Patients Living With HIV
- Polio-Like Condition in Children on Rise in the United States
- Pneumococcal H Influenzae Protein D Conjugate Vaccine Effective in Children
- Mental Health Problems in Adolescents With HIV: Overview & Expert Interview
- Epidemiology of K pneumoniae Carbapenemase-Producing Enterobacteriaceae Infections in Children
- Social Support Important in Short-Term Care for Older Adults With HIV
- High-Dose Influenza Vaccination May Benefit Transplant Recipients
- Low-Dose Methotrexate: No Effect on Endothelial Function in Patients Treated for HIV
- Updated HCV Treatment Guidelines for 2018 Published by AASLD-IDSA