Vaccines

New AAP Policy on Patient Dismissal for Vaccine Refusal May "Erode Solidarity" Among Pediatricians

New AAP Policy on Patient Dismissal for Vaccine Refusal May "Erode Solidarity" Among Pediatricians

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Others have argued that dismissal is ethically problematic because it can deprive children of comprehensive pediatric care and undermine public health.

Study Supports Development of a Vaccine for Recurrent Vulvovaginal Candidiasis

Study Supports Development of a Vaccine for Recurrent Vulvovaginal Candidiasis

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Results support further development of NDV-3A vaccine and provide guidance for meaningful clinical endpoints for immunotherapeutic management of recurrent vulvovaginal candidiasis.

WHO Issues Position Paper for Typhoid Fever Vaccine

WHO Issues Position Paper for Typhoid Fever Vaccine

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The World Health Organization recommends vaccination in cases of confirmed outbreaks of typhoid fever, although data on the use of vaccines in controlling outbreaks are very limited and research to assess the value of vaccination in these cases is strongly recommended.

MenACWY-TT Vaccine Can Be Effectively Coadministered With Routine Pediatric Immunizations

MenACWY-TT Vaccine Can Be Effectively Coadministered With Routine Pediatric Immunizations

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Study showed that DTPa-HBV-IPV/Hib and PHiD-CV coadministered with MenACWY-TT in infants and toddlers were immunogenic with an acceptable reactogenicity profile.

HPV Vaccination May Offer Protection Against Cervical Precancer

HPV Vaccination May Offer Protection Against Cervical Precancer

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The authors concluded, "There is high-certainty evidence that HPV vaccines protect against cervical precancer in adolescent girls and young women aged 15 to 26," while also indicated that future studies should have long-term follow-up.

Effect of Pneumococcal Vaccination With PCV10 on All-Cause Acute Otitis Media

Effect of Pneumococcal Vaccination With PCV10 on All-Cause Acute Otitis Media

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In this whole-population study, researchers demonstrated a 22% vaccine effect of the 10-valent pneumococcal conjugate vaccine on all-cause acute otitis media.

Vaccine for Chikungunya Prevention Gets Fast Track Designation

Vaccine for Chikungunya Prevention Gets Fast Track Designation

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The Phase 2b study is in the process of enrolling 400 people to evaluate multiple dosing regimens. PaxVax expects the results in early 2019.

The 'Attitude Roots' Underlying Antivaccination Beliefs

The 'Attitude Roots' Underlying Antivaccination Beliefs

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Although efforts to debunk antivaccination beliefs often rely on fact-based strategies, emerging evidence suggests it may be more effective to target the psychological roots of these beliefs.

Are Vaccines Associated With Multiple Sclerosis Relapse?

Are Vaccines Associated With Multiple Sclerosis Relapse?

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Researchers found there are no associations between vaccinations and multiple sclerosis relapse flares.

FDA to Review Fluzone Quadrivalent 0.5mL Dose for Younger Patients

FDA to Review Fluzone Quadrivalent 0.5mL Dose for Younger Patients

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The sBLA included clinical data from a Phase 4 study that enrolled nearly 2000 children and assessed the safety and immunogenicity of the 0.5mL dose.

Single-Dose Ebola Vaccine Durable for 1 to 2 Years

Single-Dose Ebola Vaccine Durable for 1 to 2 Years

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Study provides new data on the durability of the humoral immune response up to 2 years after single-dose injection with rVSV-ZEBOV vaccine in a population of primarily European ancestry, and additional data on durability at 1 year after vaccination in 2 African populations.

Season and Year of Birth an Emergent Risk Factor for Rotavirus

Season and Year of Birth an Emergent Risk Factor for Rotavirus

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Researchers found being born in an odd calendar year, especially in the winter or fall seasons, emerged as a risk factor for rotavirus in the postvaccine era in the United States.

MenB Vaccine Gets Breakthrough Therapy Designation for Children Ages 1-9 Years

MenB Vaccine Gets Breakthrough Therapy Designation for Children Ages 1-9 Years

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The FDA has granted Breakthrough Therapy designation to Trumenba for immunization caused by Neisseria meningitidis group B in children.

CDC: Recommendations on the Use of Heplisav-B Published

CDC: Recommendations on the Use of Heplisav-B Published

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The CDC has published ACIP recommendations regarding the use of Heplisav-B.

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

ACOG: Updated Recommendations for Influenza Vaccination During Pregnancy

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This updated Committee Opinion includes more recent data on the safety and efficacy of influenza vaccination during pregnancy, as well as recommendations for treatment and postexposure chemoprophylaxis.

Adult Caregivers Likely to Receive Influenza Vaccination From Pediatric Clinics

Adult Caregivers Likely to Receive Influenza Vaccination From Pediatric Clinics

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Adult caretaker influenza vaccination cocooning programs can prove beneficial and financially successful in private practice models where external funding is limited or not available.

Inactivated Quadrivalent Flu Vaccine Highly Efficacious in Children Aged 6-35 Months

Inactivated Quadrivalent Flu Vaccine Highly Efficacious in Children Aged 6-35 Months

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Study adds to the body of existing evidence to support universal vaccination of all children from 6 months of age, irrespective of risk status, to prevent influenza in this age group and to reduce the spread of influenza in the general population.

Efficacy of Adjuvanted vs Conventional Quadrivalent Flu Vaccine Compared

Efficacy of Adjuvanted vs Conventional Quadrivalent Flu Vaccine Compared

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MF59 adjuvanted, quadrivalent influenza vaccine (aQIV) was found to be more efficacious in preventing influenza than a non-adjuvanted conventional influenza vaccine in children aged 6 through 23 months.

An Effective Zika Vaccine May Eliminate Prenatal Infections

An Effective Zika Vaccine May Eliminate Prenatal Infections

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A vaccine against Zika virus, once available and effectively deployed, may substantially reduce prenatal infections.

Herpes Zoster in Healthy Children Linked to Varicella-Zoster Vaccination

Herpes Zoster in Healthy Children Linked to Varicella-Zoster Vaccination

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The morphology of the lesions included erythematous papules, pseudovesicles, and plaques, with associated pain in 2 and pruritus in 3 patients; systemic symptoms ranged from none to low‐grade fevers, upper respiratory symptoms, and joint pain.

Increased Risk for Acute Respiratory Illness Following Influenza Vaccine in Children

Increased Risk for Acute Respiratory Illness Following Influenza Vaccine in Children

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Among children there was an increased risk for acute respiratory illness caused by noninfluenza respiratory pathogens following influenza vaccination compared to unvaccinated children during the same period.

A Zika vaccine could virtually eliminate prenatal infections

A Zika virus vaccine shown to be of moderate to high efficacy in eliminating prenatal infections provides 90% coverage.

Improving Efforts to Prepare for Influenza Epidemics

Improving Efforts to Prepare for Influenza Epidemics

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Although substantial emphasis is placed on vaccinations in considering how to limit the spread of influenza, simple hygienic methods have been found to be the most effective and should be more widely supported.

Findings Support Nonavalent HPV Vaccine Use in Women With HIV

Findings Support Nonavalent HPV Vaccine Use in Women With HIV

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The HR-HPV types covered by the nonavalent HPV vaccine had similar clearance rates to HR-HPV types not included, and women infected with multiple anogenital HR-HPV types had lower rates of clearance than women infected with only 1 type.

Children With ASD, Younger Siblings Are Undervaccinated

Children With ASD, Younger Siblings Are Undervaccinated

Compared with the general population, children with autism spectrum disorder and their younger siblings are undervaccinated.

MenACWY-TT Vaccine Evaluated in Patients With Anatomic/Functional Asplenia

MenACWY-TT Vaccine Evaluated in Patients With Anatomic/Functional Asplenia

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Study evaluated the immunogenicity and safety of 1 and 2 doses of the quadrivalent meningococcal serogroups A, C, W, Y tetanus toxoid-conjugate vaccine in individuals with functional or anatomic asplenia.

Stronger Recommendations by PCPs for Herpes Zoster Vaccination Needed

Stronger Recommendations by PCPs for Herpes Zoster Vaccination Needed

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From January to March 2017, the researchers distributed a cross-sectional online survey to all physicians in the Division of General Internal Medicine and Clinical Innovation at NYULH, across 5 different practice settings. A total of 138 (out of 530) responded (26%).

Role of Vaccines in the Fight Against Antimicrobial Resistance

Role of Vaccines in the Fight Against Antimicrobial Resistance

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The potential role of vaccinations in combatting antimicrobial resistance (AMR) is currently undervalued. The distribution and development of new vaccines should be priorities in efforts to address the AMR crisis.

Vaccine Lessens Incidence of Herpes Zoster Complications in Immuncompetent Older Adults

Vaccine Lessens Incidence of Herpes Zoster Complications in Immuncompetent Older Adults

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Researchers reviewed clinical trial data to evaluate the efficacy of herpes zoster subunit vaccine in preventing complications, hospitalizations, and deaths.

Recombinant Influenza Vaccine Found to Be Safe in Children

Recombinant Influenza Vaccine Found to Be Safe in Children

Researchers compared the safety and immunogenicity of the quadrivalent, recombinant influenza vaccine vs the inactivated influenza vaccine in children and adolescents 6 to 17 years of age.

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