Vaccines

Pneumococcal <i>H Influenzae</i> Protein D Conjugate Vaccine Effective in Children

Pneumococcal H Influenzae Protein D Conjugate Vaccine Effective in Children

By

The burden of childhood and infant pneumonia can be effectively reduced through the use of the pneumococcal Haemophilus influenzae protein D conjugate vaccine.

Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

By

Repeated exposure to the influenza virus affects antibody quantity and quality, and strains selected for seasonal vaccines may not provide coverage sufficient for individuals frequently infected and/or vaccinated.

High Level of Population-Wide Immunity Enhances Disappearance of Sabin-2 Poliovirus

High Level of Population-Wide Immunity Enhances Disappearance of Sabin-2 Poliovirus

By

A high level of population-wide immunity at the time the oral polio vaccine 2 was withdrawn has helped to enhance the disappearance of Sabin-2 vaccine poliovirus.

HPV Vaccination Decreases High-Grade Cervical Lesions in Women

HPV Vaccination Decreases High-Grade Cervical Lesions in Women

By

From 2008 to 2015, both cervical intraepithelial neoplasia grades 2, 3 and adenocarcinoma in situ rates and cervical cancer screening declined in women age 18 to 24 years.

Improved Immune Response to Pneumococcal Vaccine in ANCA-Associated Vasculitis

Improved Immune Response to Pneumococcal Vaccine in ANCA-Associated Vasculitis

By

Suppressing cytomegalovirus may improve the immune response to a T cell-dependent pneumococcal vaccination in patients experiencing ANCA-associated vasculitis.

AAP Issues Updated Influenza Vaccine Recommendations

AAP Issues Updated Influenza Vaccine Recommendations

By

According to the Centers for Disease Control and Prevention (CDC), the 2017-2018 flu season was one of the most severe - excluding pandemics - on record.

Decline of Subacute Sclerosing Panencephalitis Mortality Linked With Increased Vaccinations

Decline of Subacute Sclerosing Panencephalitis Mortality Linked With Increased Vaccinations

By

Age-specific mortality from subacute sclerosing panencephalitis, the neurodegenerative disease caused by the measles virus, is reflective of changes in measles age distributions, and the condition could disappear in the United States if measles vaccination rates remain high.

China Withholding H7N9 Bird Flu Virus Samples From the United States

China Withholding H7N9 Bird Flu Virus Samples From the United States

Specimens of the rapidly evolving virus are needed to develop vaccines and treatments.

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

By

In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.

Prenatal Tdap Vaccination Not Linked to Autism Risk

Prenatal Tdap Vaccination Not Linked to Autism Risk

Prenatal Tdap vaccination is not associated with increased risk of autism spectrum disorder in offspring.

Safety and Immunogenicity of Tdap Vaccine Immunization During Pregnancy

Safety and Immunogenicity of Tdap Vaccine Immunization During Pregnancy

By

Immunization with Tdap vaccine during pregnancy results in higher levels of antibodies early in infancy but lower levels after the primary vaccine series.

Flu Vaccine Cuts Mortality in Rheumatoid Arthritis Patients

Flu Vaccine Cuts Mortality in Rheumatoid Arthritis Patients

Patients with rheumatoid arthritis, particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality.

HPV Vaccine Eliminates Advanced Skin Cancer in 97-Year-Old

HPV Vaccine Eliminates Advanced Skin Cancer in 97-Year-Old

The 9-valent HPV vaccine could be a therapeutic option for patients with cutaneous squamous cell carcinoma when surgical management is not an option.

Comparison of Live Attenuated vs Inactive Influenza Vaccine in Nursing Mothers

Comparison of Live Attenuated vs Inactive Influenza Vaccine in Nursing Mothers

By

Both LAIV and IIV are safe for nursing mothers, however, breast milk and serum antibody responses were higher for IIV.

Effects of Shortening the Pre-Exposure Intradermal Rabies Vaccination Schedule

Effects of Shortening the Pre-Exposure Intradermal Rabies Vaccination Schedule

By

In healthy adults, intradermal (ID) administration of a double dose of 0.1 mL (0.1 ID) of human diploid cell culture rabies vaccine over the course of 2 visits was safe and not inferior to the single-dose 3-visit ID schedule.

Promising Early Results With P27A Candidate Vaccine for Malaria Prevention

Promising Early Results With P27A Candidate Vaccine for Malaria Prevention

By

Early findings show that the P27A candidate vaccine for malaria prevention appeared to be safe and induced a strong immunogenic response with parasite growth inhibitory capacity.

Public Health Vaccine Opposition Growing in the United States

Public Health Vaccine Opposition Growing in the United States

Inverse association identified between NME rate and MMR vaccine coverage of kindergarteners

Multidose Hepatitis Vaccine Adherence in US Adults May Be Suboptimal

Multidose Hepatitis Vaccine Adherence in US Adults May Be Suboptimal

By

Adherence and completion to multidose vaccine schedules for hepatitis A, B, and A-B are low, thereby rendering vaccination ineffective.

Immunogenicity of Co-Administered Herpes Zoster, Pneumonia Vaccine Assessed

Immunogenicity of Co-Administered Herpes Zoster, Pneumonia Vaccine Assessed

By

A new study found no immunologic interference with the co-administration of Shingrix vaccine and the PCV 23 in adult patients

Human Challenge Studies in Infectious Disease: Despite Need for Rigorous Oversight, Studies Are Vital

Human Challenge Studies in Infectious Disease: Despite Need for Rigorous Oversight, Studies Are Vital

By

Barriers to challenge studies include ethical guidelines indicating that the generation of scientific knowledge should never supersede the rights and interests of research subjects.

HPV Vaccine Under Priority Review for Expanded Age Range

HPV Vaccine Under Priority Review for Expanded Age Range

By

Specifically, the types the vaccine protects against are HPV 16, 18, 31, 33, 45, 52, 58 (which cause ~90% of cervical cancer cases worldwide), and types 6 and 11 which case genital warts.

CDC: Get Vaccinated for Measles Before Traveling

CDC: Get Vaccinated for Measles Before Traveling

By

The CDC recommends 2 doses of the MMR vaccine, which provides 97% protection against measles, prior to international travel.

Varicella Zoster Vaccine Effective for Hematopoietic Stem Cell Transplant Recipients

Varicella Zoster Vaccine Effective for Hematopoietic Stem Cell Transplant Recipients

By

In a phase 3 clinical trial, early vaccination effectively prevented herpes zoster in auto-HSCT recipients.

Increase in Requirement for Influenza Vaccinations at Non-VA Hospitals

Increase in Requirement for Influenza Vaccinations at Non-VA Hospitals

At non VA hospitals, but not in VA hospitals, there was an increase in mandatory influenza vaccination requirements for health care personnel from 2013 to 2017.

No New Adverse Events Reported for DTaP Vaccination

No New Adverse Events Reported for DTaP Vaccination

No new or unexpected safety issues have been identified in association with DTaP vaccines in the US

Platform Manufacturing May Speed Pandemic Vaccine Development

Platform Manufacturing May Speed Pandemic Vaccine Development

By

With the advent of platform manufacturing technology, vaccines can be developed quickly to stop the spread of outbreaks.

CDC: Administration Errors Reported With New Shingles Vaccine

CDC: Administration Errors Reported With New Shingles Vaccine

By

Between October 20, 2017 and February 20, 2018, the Vaccine Adverse Event Reporting System (VAERS) received 155 reports involving RZV, with 13 (8%) involving an administrative error.

New AAP Policy on Patient Dismissal for Vaccine Refusal May "Erode Solidarity" Among Pediatricians

New AAP Policy on Patient Dismissal for Vaccine Refusal May "Erode Solidarity" Among Pediatricians

By

Others have argued that dismissal is ethically problematic because it can deprive children of comprehensive pediatric care and undermine public health.

Study Supports Development of a Vaccine for Recurrent Vulvovaginal Candidiasis

Study Supports Development of a Vaccine for Recurrent Vulvovaginal Candidiasis

By

Results support further development of NDV-3A vaccine and provide guidance for meaningful clinical endpoints for immunotherapeutic management of recurrent vulvovaginal candidiasis.

WHO Issues Position Paper for Typhoid Fever Vaccine

WHO Issues Position Paper for Typhoid Fever Vaccine

By

The World Health Organization recommends vaccination in cases of confirmed outbreaks of typhoid fever, although data on the use of vaccines in controlling outbreaks are very limited and research to assess the value of vaccination in these cases is strongly recommended.

Sign Up for Free e-newsletters