Vector-borne Illness

Feature Article

Placental Malaria and Risk of Malaria Infection in Childhood

Placental Malaria and Risk of Malaria Infection in Childhood

Placental malaria during pregnancy may raise the risk of malaria infection in childhood by promoting maternal microchimerism, in which the fetus acquires noninherited maternal cells during pregnancy. Maternal microchimerism may be the mechanism by which the fetus develops tolerance to malaria antigens, leading to an impaired malaria-specific immune response.

Featured Quiz

Fever, Malaise Following International Travel: A Case Study

A 15-year-old African American girl is admitted to the emergency department complaining of fever, vomiting, headache, back pain, and chills.

Latest News

FDA Grants Accelerated Approval for First US Chagas Disease Treatment

FDA Grants Accelerated Approval for First US Chagas Disease Treatment

The FDA has granted accelerated approval for benznidazole as the first US treatment of Chagas disease in children ages 2 to 12 years.

Second Dose of Tetravalent Dengue Vaccine Candidate Shows Enhanced Immunogenicity

Second Dose of Tetravalent Dengue Vaccine Candidate Shows Enhanced Immunogenicity

A tetravalent dengue vaccine candidate (TDV) was found to be safe and immunogenic in an ongoing phase 2 trial. A second TDV dose induced enhanced immunogenicity against DENV-3 and DENV-4 in children who were seronegative before vaccination, supporting the initiation of phase 3 trial to evaluate the efficacy and safety of TDV given in a 2-dose schedule 3 months apart.

Investigational Malaria Vaccine Shows Durable Response to Multiple Strains

Investigational Malaria Vaccine Shows Durable Response to Multiple Strains

3 IV doses of PfSPZ vaccine conferred protection after immunization against different Pf strains of malaria than the one the vaccine came from.

NIH Begins Study on a Universal Mosquito-Borne Diseases Vaccine

NIH Begins Study on a Universal Mosquito-Borne Diseases Vaccine

Investigational vaccine is designed to trigger an immune response to mosquito saliva rather than to a specific virus or parasite carried by mosquitoes.

Screening Reduces Risk of Transfusion-Transmitted Babesiosis

Screening Reduces Risk of Transfusion-Transmitted Babesiosis

Blood-donation screening for antibodies to and DNA from B microti was associated with a decrease in the risk of transfusion-transmitted babesiosis.

Most Promising Malaria Vaccine Offered Only Short-Lived Protection in Young Children

Most Promising Malaria Vaccine Offered Only Short-Lived Protection in Young Children

Children in study were given three doses, but manufacturer now says four doses needed.

Human Rabies Death Highlights Need for Better Education on Bat Exposure for Public

Human Rabies Death Highlights Need for Better Education on Bat Exposure for Public

A 2015 fatal human rabies case that took weeks to identify in an elderly woman after a bat encounter underscores the need for better public health outreach.

Whole Blood Pathogen Reduction System Prevents Malaria Via Transfusion

Whole Blood Pathogen Reduction System Prevents Malaria Via Transfusion

Plasmodium inactivation in whole blood reduces incidence of transfusion-transmitted malaria.

Prolonged Antibiotic Treatment Has No Added Benefit in Lyme Disease

Prolonged Antibiotic Treatment Has No Added Benefit in Lyme Disease

Longer-term antibiotic treatment does not have additional benefits on health-related quality of life among patients with symptoms attributed to Lyme disease.

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