Vector-borne Illness

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Malaria Therapy During Pregnancy Needs a Translational Booster

Malaria Therapy During Pregnancy Needs a Translational Booster

First trimester treatment for malaria could change with the results of 1 of the most robust meta-analyses to date that compared artemisinin-based therapy vs quinine.

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Fever, Malaise Following International Travel: A Case Study

A 15-year-old African American girl is admitted to the emergency department complaining of fever, vomiting, headache, back pain, and chills.

Latest News

Synovial Fluid Cell Counts Do Not Accurately Differentiate Arthritis Types

Synovial Fluid Cell Counts Do Not Accurately Differentiate Arthritis Types

Accurate and rapid diagnostics methods are needed to inform initial clinical decision making for patients with hip monoarthritis.

Vaccine for Chikungunya Prevention Gets Fast Track Designation

Vaccine for Chikungunya Prevention Gets Fast Track Designation

The Phase 2b study is in the process of enrolling 400 people to evaluate multiple dosing regimens. PaxVax expects the results in early 2019.

Vector-Borne Diseases Up More Than 2-Fold From 2004 to 2016

Vector-Borne Diseases Up More Than 2-Fold From 2004 to 2016

Vector-borne diseases represent an increasing problem in the United States, with a more than 2-fold increase in the number of annual reports from 2004 to 2016.

CDC Recommends Additional Malaria Treatment Option During Pregnancy

CDC Recommends Additional Malaria Treatment Option During Pregnancy

Women in the United States with uncomplicated malaria during the first trimester of pregnancy should be treated with the currently recommended options of either mefloquine or quinine plus clindamycin. However, when neither of these options is available, artemether-lumefantrine should be considered for treatment.

Inhaled Nitric Oxide Protects From Fine Motor Impairment in Severe Malaria

Inhaled Nitric Oxide Protects From Fine Motor Impairment in Severe Malaria

As long-term neurocognitive deficits can occur as a result of severe malaria, researchers assessed the potential neuroprotective effect of inhaled nitric oxide on children with the infection.

Previous West Nile Virus Infection May Cause Neurologic Abnormalities

Previous West Nile Virus Infection May Cause Neurologic Abnormalities

Many patients with a previous West Nile virus infection have abnormalities on neurologic examination several years after they were infected.

FDA Grants Accelerated Approval for First US Chagas Disease Treatment

FDA Grants Accelerated Approval for First US Chagas Disease Treatment

The FDA has granted accelerated approval for benznidazole as the first US treatment of Chagas disease in children ages 2 to 12 years.

Placental Malaria and Risk of Malaria Infection in Childhood

Placental Malaria and Risk of Malaria Infection in Childhood

Placental malaria during pregnancy may raise the risk of malaria infection in childhood by promoting maternal microchimerism, in which the fetus acquires noninherited maternal cells during pregnancy. Maternal microchimerism may be the mechanism by which the fetus develops tolerance to malaria antigens, leading to an impaired malaria-specific immune response.

Investigational Malaria Vaccine Shows Durable Response to Multiple Strains

Investigational Malaria Vaccine Shows Durable Response to Multiple Strains

3 IV doses of PfSPZ vaccine conferred protection after immunization against different Pf strains of malaria than the one the vaccine came from.

NIH Begins Study on a Universal Mosquito-Borne Diseases Vaccine

NIH Begins Study on a Universal Mosquito-Borne Diseases Vaccine

Investigational vaccine is designed to trigger an immune response to mosquito saliva rather than to a specific virus or parasite carried by mosquitoes.

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