Zika Virus

Safety, Efficacy of 2 Zika Virus Vaccine Trials Reported

Safety, Efficacy of 2 Zika Virus Vaccine Trials Reported

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Two trials assessing different vaccination schedules and delivery methods for Zika virus vaccine reveal the vaccines to be safe, well tolerated, and immunogenic.

Epidemiology of Pediatric Zika Virus Infection in the United States

Epidemiology of Pediatric Zika Virus Infection in the United States

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Majority of children presented with only 2 of 4 main symptoms (fever, maculopapular rash, conjunctivitis, and/or arthralgia).

Zika Virus Persists in Tears of Convalescent Patients

Zika Virus Persists in Tears of Convalescent Patients

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Although detection of Zika virus from conjunctiva has been previously reported, presence of Zika virus RNA in conjunctiva at the late convalescent phase of the disease was not known.

Growing Body of Evidence Links Zika Virus With Guillain-Barré Syndrome

Growing Body of Evidence Links Zika Virus With Guillain-Barré Syndrome

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Evidence suggests a link between the Zika virus infection and Guillain-Barré Syndrome.

Zika Virus Preferentially Infects, Kills Glioblastoma Stem Cells

Zika Virus Preferentially Infects, Kills Glioblastoma Stem Cells

The Zika virus preferentially targets glioblastoma stem cells.

CDC Guidance Update for Possible Congenital Zika Infection

CDC Guidance Update for Possible Congenital Zika Infection

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This updated interim guidance is based on current, limited data about Zika virus infection, and reflects the information available as of September 2017.

Rapid Antigen Test Differentiates Zika and Dengue Cases

Rapid Antigen Test Differentiates Zika and Dengue Cases

A rapid immunochromatography approach can differentiate dengue and Zika virus cases

Zika Infection May Lead to High Risk of Neurologic Complications

Zika Infection May Lead to High Risk of Neurologic Complications

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The Zika virus may be associated with a high risk for neurologic complications in affected adults.

Breadth of Viruses Detectable in Semen Examined

Breadth of Viruses Detectable in Semen Examined

A new research letter claims that 27 viruses can be found in human semen.

Single Mutation Contributes to Fetal Microcephaly in Zika Virus

Single Mutation Contributes to Fetal Microcephaly in Zika Virus

A single serine to glutamin substitution (S139N) in the viral polyprotein substantially increased Zika virus infectivity in both human and mouse neural progenitor cells.

Safety, Immunogenicity of Investigational Zika Vaccine Examined

Safety, Immunogenicity of Investigational Zika Vaccine Examined

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Volunteer participants received either 1 mg or 2 mg doses of the GLS-5700 vaccine over 12 weeks.

Congenital Zika, Cobalamin C Deficiency: Retinal Changes Evaluated With SD-OCT

Congenital Zika, Cobalamin C Deficiency: Retinal Changes Evaluated With SD-OCT

Retinal maldevelopment associated with congenital Zika syndrome is similar to the maldevelopment seen with cobalamin C deficiency.

Zika Virus Skews Immunosuppression During Pregnancy, Inducing Rapid Viremia

Zika Virus Skews Immunosuppression During Pregnancy, Inducing Rapid Viremia

The Zika virus thrives in pregnant women by suppressing their already dampened immune systems and running roughshod over their body's natural defenses.

Detection of Zika Virus RNA in Semen

Detection of Zika Virus RNA in Semen

The Zika virus might not last in the semen of infected men as long as previously thought.

Low Risk of Oropharangeal Zika Virus Transmission in Monkeys

Low Risk of Oropharangeal Zika Virus Transmission in Monkeys

Zika virus doesn't appear to be transmitted through saliva in rhesus monkeys.

FDA Issues Emergency Use Authorization for Multiplex Zika Virus Test

FDA Issues Emergency Use Authorization for Multiplex Zika Virus Test

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The FDA issued an Emergency Use Authorization for the Center for Infection and Immunity-ArboViroPlex rRT-PCR Test for Zika virus detection.

New Vaccines May Protect Fetuses Against Zika Virus Infection

New Vaccines May Protect Fetuses Against Zika Virus Infection

Two experimental vaccines may help protect fetuses against the Zika virus.

Eye Abnormalities May Be First Sign of Congenital Zika Virus Infection

Eye Abnormalities May Be First Sign of Congenital Zika Virus Infection

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Infants exposed to the Zika virus in utero should have their eyes examined for possible virus-related abnormalities.

Can Testing Placental Tissue Confirm Zika Infection?

Can Testing Placental Tissue Confirm Zika Infection?

Zika infection can be ruled out or confirmed by testing fetal and placental tissue according to a study published in Morbidity and Mortality Weekly Report.

CDC: Increase in Number of Counties With Zika-Carrying Mosquitoes

CDC: Increase in Number of Counties With Zika-Carrying Mosquitoes

The number of US counties with Zika-carrying mosquitoes is up.

Rate of Birth Defects Nearly 5% With Zika Confirmed Pregnancies

Rate of Birth Defects Nearly 5% With Zika Confirmed Pregnancies

About 1 in 20 women in the US territories who were infected with Zika during pregnancy had babies with possible Zika-associated birth defects.

At Least 4 Different Introductions of Zika Lead to Outbreak in Florida

At Least 4 Different Introductions of Zika Lead to Outbreak in Florida

Research shows the 2016 Zika outbreak in Florida was linked to 4 separate events that introduced and spread the virus.

New Rapid, Low-Cost Test for Zika Virus Surveillance

New Rapid, Low-Cost Test for Zika Virus Surveillance

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A new rapid, low-cost test may enable on-site detection of Zika virus in mosquitoes and human blood and semen, allowing for more efficient disease surveillance and diagnosis.

Potential Exposure of Zika Infection Low in Pregnant Women

Potential Exposure of Zika Infection Low in Pregnant Women

US women traveling to active Zika virus areas may be less likely to get infected than expected.

Zika Outbreak in US Could Mean High Economic Burden

Zika Outbreak in US Could Mean High Economic Burden

A Zika virus infection outbreak in the United States could be very costly.

Ophthalmic Exam Recommended in Infants With Congenital Zika Syndrome

Ophthalmic Exam Recommended in Infants With Congenital Zika Syndrome

Zika virus may lead to lifelong vision impairment in affected infants.

Zika Virus May Trigger Epilepsy in Infants

Zika Virus May Trigger Epilepsy in Infants

Findings suggest the need to examine how and to what extent congenital Zika virus infection and resulting brain abnormalities are associated with seizures and/or epilepsy.

NIH Begins Phase 2 Zika Vaccine Trials

NIH Begins Phase 2 Zika Vaccine Trials

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The National Institute of Allergy and Infectious Diseases began phase 2/2b of a multisite clinical trial of an investigational vaccine against the Zika virus.

Protecting America's Blood Supply From Zika Virus

Protecting America's Blood Supply From Zika Virus

Blood banks in the US are taking precautionary measures to protect blood supplies from Zika virus transmission during the upcoming mosquito season.

Human Antibody Against Zika Virus Offering New Promise

Human Antibody Against Zika Virus Offering New Promise

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The structure of a human antibody bound to the Zika virus may help in the development of antiviral medications.

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