Case-study demonstrates that epithelial cells are susceptible to congenitally acquired Zika virus.
Since 2015, California has seen many travel-related Zika virus cases, and as the population of mosquitos that spread the virus continue to expand across the state, there is a significant risk for new Zika cases.
Approximately 14% of children who were born to mothers with confirmed or possible Zika virus infection during pregnancy were identified during infancy or early childhood as having a Zika-associated birth defect.
In an updated interim guidance, the CDC now recommends that couples wait at least 3 months before attempting to conceive after possible Zika virus exposure in the male.
Multiple reports of Zika virus and West Nile virus are being investigated by Alabama health officials.
Many children of mothers with evidence of confirmed or possible Zika virus infection during pregnancy do not undergo all recommended evaluations.
Diagnostic indicators including conjunctivitis, platelet count, and monocyte count can be used to reliably distinguish between Zika virus and dengue fever.
Infectious disease experts from Emory University School of Medicine recommend that patients contemplating travel to Zika-affected areas consult with their care providers regarding travel plans and potential Zika virus testing.
Individual blood donations will no longer need to be tested for the Zika virus.
Aedes mosquitoes in California can spread the Zika virus.
Symptomatic pediatric patients infected with Zika virus generally have a mild, often nonspecific symptoms not requiring hospitalization.
Most children with Zika virus (ZIKV) infection have fever, rash, and facial or neck erythema.
Screening blood donations for Zika virus in the United States is costly with low yield.
Vector-borne diseases represent an increasing problem in the United States, with a more than 2-fold increase in the number of annual reports from 2004 to 2016.
Zika virus RNA is frequently present in the semen of men with symptomatic ZIKV infection and can persist for over 6 months.
Pregnant women may have about a 3-fold longer estimated median detection window for Zika virus RNA in serum.
A vaccine against Zika virus, once available and effectively deployed, may substantially reduce prenatal infections.
A Zika virus vaccine shown to be of moderate to high efficacy in eliminating prenatal infections provides 90% coverage.
Researchers estimated this risk among pregnant women with symptomatic Zika virus infection in French territories in the Americas.
Prompt identification may help reduce the risk for subsequent renal failure and minimize overall disease burden.
Animal model revealed a potential relationship between Zika virus infection and uteroplacental pathology that appears to affect oxygen delivery to the fetus during development.
A total of 5168 noncongenital Zika virus disease cases were reported from US states and the District of Columbia in 2016.
There was an increase in the number of birth defects potentially related to Zika virus infection from the first half of 2016 to the second half of 2016.
Although Zika virus is known to be transmitted by mosquitos, sexual contact, blood transfusion, or laboratory exposure, there is also evidence supporting maternal transmission to infants via breastfeeding, delivery, or close contact.
Severe functional limitations are reported among children with microcephaly and laboratory evidence of Zika virus infection in infancy.
Emerging neurotropic flaviviruses related to Zika virus may share Zika virus' capacity for transplacental transmission.
An investigational Zika virus vaccine was granted Fast Track designation by the FDA.
The hepatitis C treatment, sofosbuvir was found to be effective against Zika virus in a preclinical trial.
Microcephaly was associated with lack of maternal schooling, living without a partner, smoking during pregnancy, intrauterine growth restriction, vaginal delivery, and the pregnancy being the mother's first.
Two trials assessing different vaccination schedules and delivery methods for Zika virus vaccine reveal the vaccines to be safe, well tolerated, and immunogenic.
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