Zika virus RNA is frequently present in the semen of men with symptomatic ZIKV infection and can persist for over 6 months.
Pregnant women may have about a 3-fold longer estimated median detection window for Zika virus RNA in serum.
A vaccine against Zika virus, once available and effectively deployed, may substantially reduce prenatal infections.
A Zika virus vaccine shown to be of moderate to high efficacy in eliminating prenatal infections provides 90% coverage.
Researchers estimated this risk among pregnant women with symptomatic Zika virus infection in French territories in the Americas.
Prompt identification may help reduce the risk for subsequent renal failure and minimize overall disease burden.
Animal model revealed a potential relationship between Zika virus infection and uteroplacental pathology that appears to affect oxygen delivery to the fetus during development.
A total of 5168 noncongenital Zika virus disease cases were reported from US states and the District of Columbia in 2016.
There was an increase in the number of birth defects potentially related to Zika virus infection from the first half of 2016 to the second half of 2016.
Although Zika virus is known to be transmitted by mosquitos, sexual contact, blood transfusion, or laboratory exposure, there is also evidence supporting maternal transmission to infants via breastfeeding, delivery, or close contact.
Severe functional limitations are reported among children with microcephaly and laboratory evidence of Zika virus infection in infancy.
Emerging neurotropic flaviviruses related to Zika virus may share Zika virus' capacity for transplacental transmission.
An investigational Zika virus vaccine was granted Fast Track designation by the FDA.
The hepatitis C treatment, sofosbuvir was found to be effective against Zika virus in a preclinical trial.
Microcephaly was associated with lack of maternal schooling, living without a partner, smoking during pregnancy, intrauterine growth restriction, vaginal delivery, and the pregnancy being the mother's first.
Two trials assessing different vaccination schedules and delivery methods for Zika virus vaccine reveal the vaccines to be safe, well tolerated, and immunogenic.
Majority of children presented with only 2 of 4 main symptoms (fever, maculopapular rash, conjunctivitis, and/or arthralgia).
Although detection of Zika virus from conjunctiva has been previously reported, presence of Zika virus RNA in conjunctiva at the late convalescent phase of the disease was not known.
Evidence suggests a link between the Zika virus infection and Guillain-Barré Syndrome.
The Zika virus preferentially targets glioblastoma stem cells.
This updated interim guidance is based on current, limited data about Zika virus infection, and reflects the information available as of September 2017.
A rapid immunochromatography approach can differentiate dengue and Zika virus cases
The Zika virus may be associated with a high risk for neurologic complications in affected adults.
A new research letter claims that 27 viruses can be found in human semen.
A single serine to glutamin substitution (S139N) in the viral polyprotein substantially increased Zika virus infectivity in both human and mouse neural progenitor cells.
Volunteer participants received either 1 mg or 2 mg doses of the GLS-5700 vaccine over 12 weeks.
Retinal maldevelopment associated with congenital Zika syndrome is similar to the maldevelopment seen with cobalamin C deficiency.
The Zika virus thrives in pregnant women by suppressing their already dampened immune systems and running roughshod over their body's natural defenses.
The Zika virus might not last in the semen of infected men as long as previously thought.
Zika virus doesn't appear to be transmitted through saliva in rhesus monkeys.
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