Antibiotic Resistance

Epidemiology of <i>K pneumoniae</i> Carbapenemase-Producing Enterobacteriaceae Infections in Children

Epidemiology of K pneumoniae Carbapenemase-Producing Enterobacteriaceae Infections in Children

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Patients with Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae infections have multisystem disease and exposure to carbapenems and aminoglycosides.

Piperacillin-Tazobactam vs Meropenem for Resistant Bloodstream Infections

Piperacillin-Tazobactam vs Meropenem for Resistant Bloodstream Infections

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For patients with Escherichia coli or Klebsiella pneumoniae bloodstream infections and ceftriaxone resistance, treatment with piperacillin-tazobactam compared with meropenem did not result in a non-inferior 30-day mortality.

Risk Factors for Multidrug-Resistant Pathogens in Pneumonia

Risk Factors for Multidrug-Resistant Pathogens in Pneumonia

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Previous antibiotic use and mechanical invasive ventilation were risk factors for multidrug-resistant pathogens in hospital-associated or ventilator-associated pneumonia.

Relationships Between Prescribing for UTI, <i>E coli</i> Bacteremia, Resistance

Relationships Between Prescribing for UTI, E coli Bacteremia, Resistance

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New data suggest an association between general practitioners' prescribing habits for urinary tract infections and UTI-related E coli bacteremia incidence.

High Rate of ED Visits for Children Linked With Antibiotic Adverse Effects

High Rate of ED Visits for Children Linked With Antibiotic Adverse Effects

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Many antibiotic adverse drug events led to emergency department visits, particularly among young children, highlighting a need for better communication regarding the risks of overprescribing.

Minimum Inhibitory Concentrations May Predict Risk of Relapse in Tuberculosis

Minimum Inhibitory Concentrations May Predict Risk of Relapse in Tuberculosis

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Higher minimum inhibitory concentration values of isoniazid or rifampin are associated with a greater risk of relapse in drug-susceptible tuberculosis than lower MICs.

Gram-Negative Bacteria Antibiotic Susceptibility for Pneumonia in the ICU

Gram-Negative Bacteria Antibiotic Susceptibility for Pneumonia in the ICU

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Antimicrobial agents ceftazidime/avibactam and amikacin provided the best overall coverage against Gram-negative organisms isolated from patients with pneumonia in the ICU.

Resistance to Antibiotic Treatments for <i>H pylori</i> Infection

Resistance to Antibiotic Treatments for H pylori Infection

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The resistance of Helicobacter pylori to antibiotics is increasing worldwide, with primary and secondary resistance to clarithromycin, metronidazole, and levofloxacin reaching levels higher than 15%.

Risk Factors for <i>Enterobacteriaceae</i> Bacteremia Identified

Risk Factors for Enterobacteriaceae Bacteremia Identified

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Extended-spectrum β-lactamase-producing Enterobacteriaceae in urine or feces is a substantial risk factor for subsequent EPE-bloodstream infection.

<i>E. coli</i> Subclone Responsible for Prescription Errors in Urgent Care Clinic

E. coli Subclone Responsible for Prescription Errors in Urgent Care Clinic

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The majority of mismatched prescribed antibiotics for suspected UTI at an urgent care clinic among patients 70+ years old or with diabetes or urinary catheterization is likely the result of the multidrug-resistant H30 subclone of Escherichia coli ST131.

Ceftazidime/Avibactam an Effective Option in Serious Gram-Negative Infections

Ceftazidime/Avibactam an Effective Option in Serious Gram-Negative Infections

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Ceftazidime/avibactam could be a suitable alternative to carbapenem-based regimens for certain serious Gram-negative infections.

Rapid Diagnostics Reduce Time to Optimal Antimicrobial Therapy in Children

Rapid Diagnostics Reduce Time to Optimal Antimicrobial Therapy in Children

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Time to optimal antimicrobial therapy for positive blood cultures was assessed in a pediatric population.

Less Antibiotic Use Lowers Prevalence of Genetic Antibiotic Resistance Determinants

Less Antibiotic Use Lowers Prevalence of Genetic Antibiotic Resistance Determinants

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Reducing levels of antibiotic consumption in a population is an effective method for reducing the community prevalence of antibiotic resistance.

2013 to 2016 Saw No Change in Antibiotic Prescribing Practices

2013 to 2016 Saw No Change in Antibiotic Prescribing Practices

Results suggest that inappropriate prescribing of antibiotics remains widespread, despite the concurrent release of several guideline-based best practices intended to reduce inappropriate antibiotic consumption.

Pristinamycin Effective, Well-Tolerated Treatment for <i>Mycoplasma genitalium</i>

Pristinamycin Effective, Well-Tolerated Treatment for Mycoplasma genitalium

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The increasing prevalence of macrolide resistance underscores the need for research focused on identifying a safe and effective treatment for Mycoplasma genitalium.

Trends of <i>S pneumoniae, H influenzae</i> Antibiotic Resistance in Children

Trends of S pneumoniae, H influenzae Antibiotic Resistance in Children

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Study analyzed the trends of nasopharyngeal carriage and antibiotic resistance of Streptococcus pneumoniae, Haemophilus influenza, and Moraxella catarrhalis isolated from young children with acute otitis media during a 16-year period.

FDA Announces New Website to Help Clinicians Make Appropriate Antibiotic Choices

FDA Announces New Website to Help Clinicians Make Appropriate Antibiotic Choices

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The FDA announced a new website that provides direct access to information about appropriate antibiotic choices.

Antimicrobial Resistance Research Threatened by Budget Cuts

Antimicrobial Resistance Research Threatened by Budget Cuts

Proposed budget cuts from the Trump administration can seriously hamper efforts to address antimicrobial resistance.

Are Antibiotic Stewardship Programs the Antidote to Antibiotic Overuse?

Are Antibiotic Stewardship Programs the Antidote to Antibiotic Overuse?

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Optimizing outcomes with an antibiotic stewardship programs requires a team approach that involves point-of-care providers.

Long-Term Behavioral Interventions on Inappropriate Antibiotic Prescribing

Long-Term Behavioral Interventions on Inappropriate Antibiotic Prescribing

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Inappropriate prescribing of antibiotics is a contributing factor in antibiotic resistance.

Combating Irrational and Inappropriate Antibiotic Prescribing Practices

Combating Irrational and Inappropriate Antibiotic Prescribing Practices

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A substantial portion of cases of antibiotic overprescription are linked to overdiagnosis of conditions such as sinusitis and otitis media without meeting diagnostic criteria and with high variability in diagnosis by race and by clinician.

Fluoroquinolone-Resistant <i>E coli</i>: Prominent Complication in Prostate Biopsy

Fluoroquinolone-Resistant E coli: Prominent Complication in Prostate Biopsy

The most common complication of prostate biopsy is infection, with mild bleeding also reported.

Challenges in Managing Hospital-Acquired Pneumonia

Challenges in Managing Hospital-Acquired Pneumonia

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Diagnosis is one of the primary difficulties in managing hospital acquired pneumonia.

Last-Resort Gonorrhea Treatment Sees Resistance in 66% of Countries

Last-Resort Gonorrhea Treatment Sees Resistance in 66% of Countries

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World Health Organization (WHO) reports treating gonorrhea is "much harder, and sometimes impossible, to treat" due to antibiotic resistance.

Decrease Rate of <i>S aureus</i> Resistance Seen With Certain Antibiotics

Decrease Rate of S aureus Resistance Seen With Certain Antibiotics

In recent years, Staphlococcus aureus infections have been more susceptible to key antibiotics.

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