Antibiotics, Antimicrobial Resistance

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Re-Assessing Renal Dose Adjustments of Antibiotics: Expert Q&A

Re-Assessing Renal Dose Adjustments of Antibiotics: Expert Q&A

For patients with serious infectious diseases, the first 48 hours represent a critical window for antibiotic administration.

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Cefiderocol for the Treatment of Complicated Gram-Negative UTIs

Cefiderocol for the Treatment of Complicated Gram-Negative UTIs

For the treatment of complicated UTI in people with MDR gram-negative infections, treatment with cefiderocol may be noninferior to imipenem cilastatin.

Shorter Antibiotic Course Noninferior for Gram-Negative Bacteremia

Shorter Antibiotic Course Noninferior for Gram-Negative Bacteremia

A 7-day antibiotic course has demonstrated noninferiority compared with a 14-day course in treating uncomplicated gram-negative bacteremia.

Antibiotic Use in Neonatal Settings in Need of Improvement

Antibiotic Use in Neonatal Settings in Need of Improvement

Significant gaps exist between CDC recommendations to improve antibiotic use and antibiotic practices in neonates.

Antibiotic Recalled After Rubber Flecks Found in Reconstituted Vials

Antibiotic Recalled After Rubber Flecks Found in Reconstituted Vials

The issue was identified upon standard visual inspection before administration to the patient and was not observed prior to reconstitution.

Adjunctive Cefiderocol Treats XDR P aeruginosa Endocarditis

Adjunctive Cefiderocol Treats XDR P aeruginosa Endocarditis

Cefiderocol, a novel siderophore cephalosporin, may be successful in patients with persistently bacteremic nosocomial native aortic valve endocarditis.

MIC Levels of Resistance Affect H pylori Eradication

MIC Levels of Resistance Affect H pylori Eradication

Minimum inhibitory concentration levels of resistance to either clarithromycin or metronidazole may play a role in Helicobacter pylori therapy outcome.

Antibiotics May Be Beneficial in Children With Prolonged Wet Cough

Antibiotics May Be Beneficial in Children With Prolonged Wet Cough

In children with a prolonged wet cough, antibiotics may improve clinical cure and reduce progression of illness.

Infective Endocarditis Incidence Increased After 2007 AHA Recommendations

Infective Endocarditis Incidence Increased After 2007 AHA Recommendations

The 2007 AHA recommendation for antibiotic prophylaxis for only patients at high risk for infective endocarditis may result in increased incidence of the infection.

Antibiotic Prescribing for CAP May Differ in Pediatric Specialty Hospitals

Antibiotic Prescribing for CAP May Differ in Pediatric Specialty Hospitals

Compared with those at children's hospitals, children receiving CAP care at other hospital types are less likely to be treated as per national guidelines.

Broad-Spectrum Antimicrobial Combination for Corneal Infection Treatment

Broad-Spectrum Antimicrobial Combination for Corneal Infection Treatment

Combination polymyxin B/trimethoprim ophthalmic formulation containing rifampicin may represent a new agent for the treatment of bacterial keratitis.

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