Relationships Between Prescribing for UTI, E coli Bacteremia, Resistance
Investigators make the recommendation for use of nitrofurantoin when antibiotics for a UTI are necessary.
According to data published in the International Journal of Antimicrobial Agents, there is an association between general practitioners' prescribing habits for urinary tract infections (UTIs) and UTI-related Escherichia coli bacteremia incidence at the practice level, and higher prescribing of trimethoprim is associated with higher incidence of trimethoprim-resistant bacteremia.
This national ecologic study was carried out with data aggregated at the general practitioner practice level on all adult female patients with reported UTI-related E coli bacteremia in England from 2012 to 2014. A total of 20,274 patients were included from 5916 practices.