antibiotics

Antibiotic Selection Pressure Causally Linked to Macrolide Resistome

Antibiotic Selection Pressure Causally Linked to Macrolide Resistome

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Communities randomly assigned to less frequent antibiotic use had significantly lower prevalence of genetic antibiotic resistance determinants.

No Reduction in Antibiotic Use With Procalcitonin-Guided Therapy in the ED

No Reduction in Antibiotic Use With Procalcitonin-Guided Therapy in the ED

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Procalcitonin-guided therapy did not reduce the number of antibiotic prescriptions among patients presenting to the ED with fever.

Generic Quality Indicators Developed for Responsible Antibiotic Usage

Generic Quality Indicators Developed for Responsible Antibiotic Usage

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A study was conducted with a goal of developing a set of generic quality indicators for the safe and appropriate use of antibiotic agents.

Ibuprofen Inferior to Pivmecillinam for Uncomplicated UTI in Women

Ibuprofen Inferior to Pivmecillinam for Uncomplicated UTI in Women

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A study evaluated whether uncomplicated UTIs in women could be treated without antibiotics.

Empirical Use of Antibiotics for Resistant Infections Not Associated With Survival

Empirical Use of Antibiotics for Resistant Infections Not Associated With Survival

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Researchers found no association between starting colistin before final culture results and survival at 14 and 28 days.

Removing Low-Risk Penicillin Allergy Label Leads to Healthcare Cost Savings

Removing Low-Risk Penicillin Allergy Label Leads to Healthcare Cost Savings

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Children deemed low risk who were tested for penicillin allergy tolerated the medication within the following year without serious adverse or allergic reactions.

Kidney Stones Linked to Oral Antibiotics

Kidney Stones Linked to Oral Antibiotics

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Use of certain antibiotics may be contributing to the rise of kidney stones among children and adults.

IV Combo Antibiotic Recalled Due to Potential for Decreased Potency

IV Combo Antibiotic Recalled Due to Potential for Decreased Potency

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The 36 recalled lots were manufactured by Hospira and marketed by Apotex.

Less Antibiotic Use Lowers Prevalence of Genetic Antibiotic Resistance Determinants

Less Antibiotic Use Lowers Prevalence of Genetic Antibiotic Resistance Determinants

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Reducing levels of antibiotic consumption in a population is an effective method for reducing the community prevalence of antibiotic resistance.

UTI Treatment Success in Women Greater With Nitrofurantoin vs Fosfomycin

UTI Treatment Success in Women Greater With Nitrofurantoin vs Fosfomycin

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Five-day nitrofurantoin may be a better alternative than single-dose fosfomycin for treating uncomplicated UTI in women.

Antibiotic Cycling, Mixing Does Not Prevent Gram-Negative Antibiotic Resistance

Antibiotic Cycling, Mixing Does Not Prevent Gram-Negative Antibiotic Resistance

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Findings do not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods, with third-generation or fourth-generation cephalosporins, piperacillin-tazobactam, and carbapenems reduces the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.

How Important Is the Timing of Antibiotics for Surviving Sepsis?

How Important Is the Timing of Antibiotics for Surviving Sepsis?

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Early antibiotic administration in treating infection has evident biological plausibility, however, time-sensitivity to outcomes appears to be most relevant in septic shock.

Critical Need to Reduce Pediatric Prophylactic Antimicrobial Prescriptions Worldwide

Critical Need to Reduce Pediatric Prophylactic Antimicrobial Prescriptions Worldwide

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Cross-sectional survey represents the first assessment of antimicrobial prescription practices for prophylaxis in pediatric patients hospitalized worldwide.

Fluoroquinolone Use May Increase Risk for Aortic Aneurysm and Dissection

Fluoroquinolone Use May Increase Risk for Aortic Aneurysm and Dissection

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Additional studies are needed to investigate whether there are differences between individual fluoroquinolones with respect to the risk for aortic aneurysm.

It Costs $2.2 Billion a Year to Treat Antibiotic Resistance

It Costs $2.2 Billion a Year to Treat Antibiotic Resistance

The need for innovative new infection prevention programs, antibiotics, and vaccines to prevent and treat antibiotic-resistant infections is an international priority.

Novel Drug Combinations, Dosing Strategies Needed for <i>E faecalis</i> Bloodstream Infections

Novel Drug Combinations, Dosing Strategies Needed for E faecalis Bloodstream Infections

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Review highlights available treatment options and their limitations and provides direction for investigation of future novel combination therapies to further aid in the treatment of Enterococcus faecalis infective endocarditis.

CDC: Aggressive Action Needed to Contain Antibiotic Resistance

CDC: Aggressive Action Needed to Contain Antibiotic Resistance

Early aggressive action should be taken to prevent the spread of bacteria harboring unusual resistance genes.

Antibiotics, Acid-Suppressive Medications Tied to Allergic Disease

Antibiotics, Acid-Suppressive Medications Tied to Allergic Disease

The use of acid-suppressive medications and antibiotics during the first 6 months of infancy is tied to subsequent development of allergic disease.

2013 to 2016 Saw No Change in Antibiotic Prescribing Practices

2013 to 2016 Saw No Change in Antibiotic Prescribing Practices

Results suggest that inappropriate prescribing of antibiotics remains widespread, despite the concurrent release of several guideline-based best practices intended to reduce inappropriate antibiotic consumption.

Role of Vaccines in the Fight Against Antimicrobial Resistance

Role of Vaccines in the Fight Against Antimicrobial Resistance

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The potential role of vaccinations in combatting antimicrobial resistance (AMR) is currently undervalued. The distribution and development of new vaccines should be priorities in efforts to address the AMR crisis.

Firvanq Availability Replaces Need for Compounded Oral Vancomycin Solution

Firvanq Availability Replaces Need for Compounded Oral Vancomycin Solution

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FIRVANQ is commercially available in 25 and 50 mg/mL strengths in convenient 150 mL and 300 mL sizes.

<i>H pylori</i> Treatment Tied to Lower Metachronous Gastric Cancer Risk

H pylori Treatment Tied to Lower Metachronous Gastric Cancer Risk

Helicobacter pylori treatment is associated with a reduced rate of metachronous gastric cancer.

Brucellosis Treatment: Rifampicin vs Streptomycin

Brucellosis Treatment: Rifampicin vs Streptomycin

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The findings of this study indicated that rifampicin therapy significantly increased the risk of overall failure and relapse compared with streptomycin.

Lower Antibiotic Prescribing Rates Linked to Integrative Medicine Training

Lower Antibiotic Prescribing Rates Linked to Integrative Medicine Training

Additional treatment strategies for common primary care infections used by integrative medicine general practitioners should be explored to see if they could be used to assist in the fight against antimicrobial resistance.

Adjunctive Antibiotic Therapy Yields Modest Benefit in Uncomplicated Skin Abscesses

Adjunctive Antibiotic Therapy Yields Modest Benefit in Uncomplicated Skin Abscesses

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Trimethoprim and sulfamethoxazole or clindamycin confer a modest benefit for several important outcomes, but this is offset by a similar risk for adverse effects.

Treatment for MRSA Complicated Bacteremia and Infective Endocarditis

Treatment for MRSA Complicated Bacteremia and Infective Endocarditis

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Further studies are warranted to assess the efficacy and safety of fosfomycin plus imipenem against methicillin-resistant Staphylococcus aureus complicated infections.

Antibiotic Rotation in ICU Does Not Reduce Prevalence of Antibiotic-Resistant Bacteria

Antibiotic Rotation in ICU Does Not Reduce Prevalence of Antibiotic-Resistant Bacteria

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Findings from the study did not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods reduced the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.

Effectiveness of Meropenem-Vaborbactam for Complicated UTI Treatment

Effectiveness of Meropenem-Vaborbactam for Complicated UTI Treatment

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Evaluating treatment with meropenem/vaborbactam to piperacillin-tazobactam in patients with complicated UTIs.

FDA: Clarithromycin May Increase Long-Term Risk for Heart Problems, Death

FDA: Clarithromycin May Increase Long-Term Risk for Heart Problems, Death

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The recommendation was made after the FDA reviewed the results of a 10-year follow-up of the CLARICOR trial, which investigated the effects of clarithromycin in patients with stable coronary heart disease.

Characteristics Associated With Inappropriate Antibiotic Prescribing

Characteristics Associated With Inappropriate Antibiotic Prescribing

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Investigators identified patient, provider, and practice characteristics associated with antibiotic prescribing in an attempt to determine factors contributing to inappropriate antimicrobial use.

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