Communities randomly assigned to less frequent antibiotic use had significantly lower prevalence of genetic antibiotic resistance determinants.
Procalcitonin-guided therapy did not reduce the number of antibiotic prescriptions among patients presenting to the ED with fever.
A study was conducted with a goal of developing a set of generic quality indicators for the safe and appropriate use of antibiotic agents.
A study evaluated whether uncomplicated UTIs in women could be treated without antibiotics.
Researchers found no association between starting colistin before final culture results and survival at 14 and 28 days.
Children deemed low risk who were tested for penicillin allergy tolerated the medication within the following year without serious adverse or allergic reactions.
Use of certain antibiotics may be contributing to the rise of kidney stones among children and adults.
The 36 recalled lots were manufactured by Hospira and marketed by Apotex.
Reducing levels of antibiotic consumption in a population is an effective method for reducing the community prevalence of antibiotic resistance.
Five-day nitrofurantoin may be a better alternative than single-dose fosfomycin for treating uncomplicated UTI in women.
Findings do not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods, with third-generation or fourth-generation cephalosporins, piperacillin-tazobactam, and carbapenems reduces the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.
Early antibiotic administration in treating infection has evident biological plausibility, however, time-sensitivity to outcomes appears to be most relevant in septic shock.
Cross-sectional survey represents the first assessment of antimicrobial prescription practices for prophylaxis in pediatric patients hospitalized worldwide.
Additional studies are needed to investigate whether there are differences between individual fluoroquinolones with respect to the risk for aortic aneurysm.
The need for innovative new infection prevention programs, antibiotics, and vaccines to prevent and treat antibiotic-resistant infections is an international priority.
Review highlights available treatment options and their limitations and provides direction for investigation of future novel combination therapies to further aid in the treatment of Enterococcus faecalis infective endocarditis.
Early aggressive action should be taken to prevent the spread of bacteria harboring unusual resistance genes.
The use of acid-suppressive medications and antibiotics during the first 6 months of infancy is tied to subsequent development of allergic disease.
Results suggest that inappropriate prescribing of antibiotics remains widespread, despite the concurrent release of several guideline-based best practices intended to reduce inappropriate antibiotic consumption.
The potential role of vaccinations in combatting antimicrobial resistance (AMR) is currently undervalued. The distribution and development of new vaccines should be priorities in efforts to address the AMR crisis.
FIRVANQ is commercially available in 25 and 50 mg/mL strengths in convenient 150 mL and 300 mL sizes.
Helicobacter pylori treatment is associated with a reduced rate of metachronous gastric cancer.
The findings of this study indicated that rifampicin therapy significantly increased the risk of overall failure and relapse compared with streptomycin.
Additional treatment strategies for common primary care infections used by integrative medicine general practitioners should be explored to see if they could be used to assist in the fight against antimicrobial resistance.
Trimethoprim and sulfamethoxazole or clindamycin confer a modest benefit for several important outcomes, but this is offset by a similar risk for adverse effects.
Further studies are warranted to assess the efficacy and safety of fosfomycin plus imipenem against methicillin-resistant Staphylococcus aureus complicated infections.
Findings from the study did not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods reduced the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.
Evaluating treatment with meropenem/vaborbactam to piperacillin-tazobactam in patients with complicated UTIs.
The recommendation was made after the FDA reviewed the results of a 10-year follow-up of the CLARICOR trial, which investigated the effects of clarithromycin in patients with stable coronary heart disease.
Investigators identified patient, provider, and practice characteristics associated with antibiotic prescribing in an attempt to determine factors contributing to inappropriate antimicrobial use.
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