Subsequent risk increased with infections requiring hospitalization, treatment with anti-infective agents.
For patients with septic shock and high circulating endotoxin levels, adding polymyxin B hemoperfusion treatment did not improve 28-day mortality rate.
Treatment for cutaneous leishmaniasis caused by Leishmania braziliensis, using 15% paromomycin-Aquaphilic, was superior to a negative vehicle control.
Nearly all isolates from infants with botulism in Californian are susceptible to most clinically used antibiotics.
Addiction Medicine Consultation Improves Antibiotic Compliance in Patients with Opioid Use DisordersDecember 03, 2018
Patients with opioid use disorders who required hospitalization with lengthy antibiotic therapy had better outcomes with addiction medicine consultation.
Investigators examined tolerability, effectiveness, and safety profile of topical antibacterial agent ozenoxacin in adults and children with impetigo.
For patients with serious infectious diseases, the first 48 hours represent a critical window for antibiotic administration.
Antibiotic use in children <24 months of age is associated with a slightly higher body weight at 5 years of age.
A transient resistance to rifampin may emerge in patients after taking rifaximin.
Six-week antibiotic treatment is sufficient for early, spinal surgery site infections.
Azithromycin and amoxicillin-clavulanate are equally effective for resolving nonsevere bronchiectasis in children.
A novel service to target appropriate antimicrobial prescription and improve antibiotic stewardship shows potential according.
Adding glycopeptide to the spacer in 2-stage exchange procedures for periprosthetic joint infections reduces positive cultures during re-implantation.
Almost half of parents report saving leftover antibiotics, and almost three-quarters of these parents subsequently divert the antibiotics.
Despite notable advances in medical care, infections due to Pseudomonas aeruginosa remain problematic and are a major public health concern.
Contepo, an investigational epoxide intravenous (IV) antibiotic, has broad spectrum activity against Gram-negative and Gram-positive pathogens, including multi-drug resistant strains such as ESBL-producing Enterobacteriaceae.
Prescription of antibiotics, acid-suppressing meds in first two years of life linked to childhood obesity.
A merger of data from 2 reviews found no place for antibiotics in adults with uncomplicated acute rhinosinusitis.
Probiotics provided to reduce the risk for common acute infections may be associated with reduced antibiotic use in infants and children.
There is considerable variability in the geographic availability of antibiotics.
Patients with Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae infections have multisystem disease and exposure to carbapenems and aminoglycosides.
For patients with Escherichia coli or Klebsiella pneumoniae bloodstream infections and ceftriaxone resistance, treatment with piperacillin-tazobactam compared with meropenem did not result in a non-inferior 30-day mortality.
The 68-year-old patient reported having a fever for 1 week followed by progressive, painful swelling on the right side of his neck for 2 months.
For infants with uncomplicated, late-onset GBS bacteremia, a shortened IV course of antibiotic therapy is sometimes prescribed and is associated with low rates of disease recurrence and treatment failure.
Daily prophylaxis with TMP-SMX was not associated with change in risk for skin and soft tissue or sino-pulmonary infections, or pharyngitis in children.
The inappropriate use of antibiotics as prophylaxis and treatment in acute pancreatitis is common, highlighting the efforts required for antibiotic stewardship.
In acute ischemic or hemorrhagic stroke, prophylactic antibiotics reduce the overall infection rate, but do not reduce the risk for pneumonia, death, or dependency.
Antipseudomonal combination therapy has shown poorer efficacy than antipseudomonal monotherapy in individuals with suspected pseudomonal pneumonia.
Treatment with intravenous and oral delafloxacin, a fluoroquinolone antibiotic with gram-negative and gram-positive activity, was comparable to vancomycin/aztreonam in improving clinical signs and symptoms in acute bacterial and skin structure infections.
No significant differences in clinical cure rates were observed between short-course and prolonged-course antimicrobial therapy in patients with intraabdominal infections.
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Infectious Disease Advisor Articles
- Topical Antibacterial Agent Effective for Treatment of Impetigo
- Novel H pylori Eradication Therapy Effective in Phase 3 Trial
- Polymyxin B Hemoperfusion Does Not Change Mortality Rate in Septic Shock
- Addiction Medicine Consultation Improves Antibiotic Compliance in Patients with Opioid Use Disorders
- Guideline Adoption for Childhood Community-Acquired Pneumonia