Antibiotics

No Effect of IDU on Postoperative Mortality in Infective Endocarditis

No Effect of IDU on Postoperative Mortality in Infective Endocarditis

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Early postoperative mortality may not differ between infective endocarditis caused by IDU and non- IDU causes.

Fecal Microbiota Transplantation and Vancomycin for Recurrent <i>C difficile</i>

Fecal Microbiota Transplantation and Vancomycin for Recurrent C difficile

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The combination of vancomycin and fecal microbiota transplantation was found to be superior to fidaxomicin or vancomycin for patients with recurrent CDI.

Practices Vary in Treating Adult <i>Staphylococcus aureus</i> Bacteremia

Practices Vary in Treating Adult Staphylococcus aureus Bacteremia

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Practices vary among clinicians in diagnosing and managing Staphylococcus aureus bacteremia in adults.

ASSET Score Provides Reliable Indication for IV Antibiotics in Children With Cellulitis

ASSET Score Provides Reliable Indication for IV Antibiotics in Children With Cellulitis

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The Area, Systemic features, Swelling, Eye, Tenderness Score shows reliability, and applicability for use of IV antibiotics in a child with cellulitis.

FDA to Review 2 Antibacterial Agents for Potentially Life-Threatening Infections

FDA to Review 2 Antibacterial Agents for Potentially Life-Threatening Infections

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Both filings have been granted Priority Review by the Agency.

Prolonged Intermittent Renal Replacement Therapy May Result in Suboptimal Colistin Level

Prolonged Intermittent Renal Replacement Therapy May Result in Suboptimal Colistin Level

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Prolonged intermittent renal replacement therapy may eliminate as much as half of the daily dose of colistin in patients who are critically ill.

Ceftaroline Every 8 Hours Noninferior to 12 Hour Dosing

Ceftaroline Every 8 Hours Noninferior to 12 Hour Dosing

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Ceftaroline 600 mg every 8 hours has demonstrated tolerability in individuals with complicated skin and soft tissue infection.

Scenario-Based Survey of Empiric Antibiotic Treatment Thresholds

Scenario-Based Survey of Empiric Antibiotic Treatment Thresholds

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80 to 90% pathogen coverage was acceptable to physicians as a threshold for managing patients with mild and severe sepsis from bacterial infections.

Review Shares Best Practices for Evaluating Penicillin Allergy

Review Shares Best Practices for Evaluating Penicillin Allergy

Verifying reported allergies necessary to improve outcomes, prevent antibiotic resistance

Bacteria Bystanders Play Important Role in Antibiotic Resistance Development

Bacteria Bystanders Play Important Role in Antibiotic Resistance Development

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It is vital to consider the antibiotic exposures of "bystander" pathogens, in addition to the target organism, and consequences on antibiotic resistance.

Infections, Antibiotics Associated With Subsequent Increased Risk for Mental Disorders in Youth

Infections, Antibiotics Associated With Subsequent Increased Risk for Mental Disorders in Youth

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The risk for mental disorders increased after severe infections requiring hospitalizations in children.

Inappropriate Antibiotic Rx Common in Privately Insured

Inappropriate Antibiotic Rx Common in Privately Insured

Less than half of all outpatient antibiotic prescription fills by privately insured nonelderly adults and children in the United States are appropriate or potentially appropriate.

Unique Presentation of SJS in a Female Patient Treated With TMP-SMX

Unique Presentation of SJS in a Female Patient Treated With TMP-SMX

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The patient, who presented to the clinical office complaining of dysuria, was diagnosed with a urinary tract infection and was prescribed TMP-SMX.

Antibiotics Often Inappropriately Prescribed for Bronchiolitis in ED

Antibiotics Often Inappropriately Prescribed for Bronchiolitis in ED

Most children younger than 2 years with bronchiolitis seen in U.S. emergency departments and prescribed antibiotics have no documented bacterial coinfection.

Cefiderocol for the Treatment of Complicated Gram-Negative UTIs

Cefiderocol for the Treatment of Complicated Gram-Negative UTIs

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For the treatment of complicated UTI in people with MDR gram-negative infections, treatment with cefiderocol may be noninferior to imipenem cilastatin.

Shorter Antibiotic Course Noninferior for Gram-Negative Bacteremia

Shorter Antibiotic Course Noninferior for Gram-Negative Bacteremia

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A 7-day antibiotic course has demonstrated noninferiority compared with a 14-day course in treating uncomplicated gram-negative bacteremia.

Antibiotic Use in Neonatal Settings in Need of Improvement

Antibiotic Use in Neonatal Settings in Need of Improvement

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Significant gaps exist between CDC recommendations to improve antibiotic use and antibiotic practices in neonates.

Adjunctive Cefiderocol Treats XDR <i>P aeruginosa</i> Endocarditis

Adjunctive Cefiderocol Treats XDR P aeruginosa Endocarditis

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Cefiderocol, a novel siderophore cephalosporin, may be successful in patients with persistently bacteremic nosocomial native aortic valve endocarditis.

Antibiotic Recalled After Rubber Flecks Found in Reconstituted Vials

Antibiotic Recalled After Rubber Flecks Found in Reconstituted Vials

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The issue was identified upon standard visual inspection before administration to the patient and was not observed prior to reconstitution.

MIC Levels of Resistance Affect <i>H pylori</i> Eradication

MIC Levels of Resistance Affect H pylori Eradication

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Minimum inhibitory concentration levels of resistance to either clarithromycin or metronidazole may play a role in Helicobacter pylori therapy outcome.

Antibiotics May Be Beneficial in Children With Prolonged Wet Cough

Antibiotics May Be Beneficial in Children With Prolonged Wet Cough

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In children with a prolonged wet cough, antibiotics may improve clinical cure and reduce progression of illness.

Infective Endocarditis Incidence Increased After 2007 AHA Recommendations

Infective Endocarditis Incidence Increased After 2007 AHA Recommendations

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The 2007 AHA recommendation for antibiotic prophylaxis for only patients at high risk for infective endocarditis may result in increased incidence of the infection.

Antibiotic Prescribing for CAP May Differ in Pediatric Specialty Hospitals

Antibiotic Prescribing for CAP May Differ in Pediatric Specialty Hospitals

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Compared with those at children's hospitals, children receiving CAP care at other hospital types are less likely to be treated as per national guidelines.

Broad-Spectrum Antimicrobial Combination for Corneal Infection Treatment

Broad-Spectrum Antimicrobial Combination for Corneal Infection Treatment

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Combination polymyxin B/trimethoprim ophthalmic formulation containing rifampicin may represent a new agent for the treatment of bacterial keratitis.

Emergency Department Overcrowding Associated With Delayed Antibiotics in Patients With Sepsis

Emergency Department Overcrowding Associated With Delayed Antibiotics in Patients With Sepsis

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Crowding in the emergency department was associated with the timely administration of antibiotics for patients presenting with sepsis.

GI Microbiota and Carbapenem-Resistant Pseudomonas aeruginosa Colonization Risk

GI Microbiota and Carbapenem-Resistant Pseudomonas aeruginosa Colonization Risk

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Decreases in abundance of several taxa may be linked to increased risk for carbapenem-resistant P aeruginosa colonization-acquisition ICU patients.

IDSA Issues Updated Guidelines on Outpatient Parenteral Antimicrobial Therapy

IDSA Issues Updated Guidelines on Outpatient Parenteral Antimicrobial Therapy

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The Infectious Diseases Society of America has updated their 2004 clinical practice guideline on outpatient parenteral antimicrobial therapy.

Unnecessary Antibiotic Use Linked to Lack of Testing and Unspecified Diagnosis

Unnecessary Antibiotic Use Linked to Lack of Testing and Unspecified Diagnosis

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The unnecessary use of antibiotics is associated with an unspecified diagnosis and a lack of microbial testing.

Bacterial Vaginosis Treatment Does Not Reduce Late Miscarriages, Preterm Birth

Bacterial Vaginosis Treatment Does Not Reduce Late Miscarriages, Preterm Birth

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No evidence for reduction in risk for late miscarriage or spontaneous preterm birth as a result of screening and treatment for bacterial vaginosis.

In Vivo Activity of Cefiderocol Against Resistant Gram-Negative Bacteria

In Vivo Activity of Cefiderocol Against Resistant Gram-Negative Bacteria

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The activity of siderophore cephalosporin cefiderocol against carbapenem-resistant gram-negative Enterobacteriaceae was determined and published as a brief report.

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