Additional studies are needed to investigate whether there are differences between individual fluoroquinolones with respect to the risk for aortic aneurysm.
The need for innovative new infection prevention programs, antibiotics, and vaccines to prevent and treat antibiotic-resistant infections is an international priority.
Review highlights available treatment options and their limitations and provides direction for investigation of future novel combination therapies to further aid in the treatment of Enterococcus faecalis infective endocarditis.
Early aggressive action should be taken to prevent the spread of bacteria harboring unusual resistance genes.
The use of acid-suppressive medications and antibiotics during the first 6 months of infancy is tied to subsequent development of allergic disease.
Results suggest that inappropriate prescribing of antibiotics remains widespread, despite the concurrent release of several guideline-based best practices intended to reduce inappropriate antibiotic consumption.
The potential role of vaccinations in combatting antimicrobial resistance (AMR) is currently undervalued. The distribution and development of new vaccines should be priorities in efforts to address the AMR crisis.
FIRVANQ is commercially available in 25 and 50 mg/mL strengths in convenient 150 mL and 300 mL sizes.
Helicobacter pylori treatment is associated with a reduced rate of metachronous gastric cancer.
The findings of this study indicated that rifampicin therapy significantly increased the risk of overall failure and relapse compared with streptomycin.
Additional treatment strategies for common primary care infections used by integrative medicine general practitioners should be explored to see if they could be used to assist in the fight against antimicrobial resistance.
Trimethoprim and sulfamethoxazole or clindamycin confer a modest benefit for several important outcomes, but this is offset by a similar risk for adverse effects.
Further studies are warranted to assess the efficacy and safety of fosfomycin plus imipenem against methicillin-resistant Staphylococcus aureus complicated infections.
Findings from the study did not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods reduced the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.
Evaluating treatment with meropenem/vaborbactam to piperacillin-tazobactam in patients with complicated UTIs.
The recommendation was made after the FDA reviewed the results of a 10-year follow-up of the CLARICOR trial, which investigated the effects of clarithromycin in patients with stable coronary heart disease.
Investigators identified patient, provider, and practice characteristics associated with antibiotic prescribing in an attempt to determine factors contributing to inappropriate antimicrobial use.
For pregnant women in their first trimester, a 2011 Committee Opinion from the ACOG recommended that sulfonamides and nitrofurantoin may be prescribed only if other antimicrobial therapies are deemed clinically inappropriate.
Patient, practice, and provider characteristics are associated with inappropriate antimicrobial prescribing in the outpatient setting.
Study analyzed the trends of nasopharyngeal carriage and antibiotic resistance of Streptococcus pneumoniae, Haemophilus influenza, and Moraxella catarrhalis isolated from young children with acute otitis media during a 16-year period.
Iclaprim was noninferior to vancomycin with respect to the early clinical response at an early time point in the treatment of ABSSSI caused or suspected to be caused by gram-positive organisms.
Long-term oral macrolide administration may increase macrolide-resistant Propionibacterium acnes.
The CDC has released new data in its Antibiotic Resistance Investment Map on the progress in combating antibiotic resistance.
Developing alternative, non-antibiotic treatments for certain "self-limiting infections" may help preserve the effectiveness of antibiotics.
A new immunotherapy approach has shown promise in it's first-in-human trial for antibiotic-resistant bacteria.
Broad-spectrum antibiotics are not associated with better clinical or patient-centered outcomes compared with narrow-spectrum antibiotics in pediatric acute RTI.
Using whole-genome sequencing, investigators determined that genetically different plasmids from antibiotic-resistant strains emerged in Salmonella enterica serotype Typhimurium in the late 1950s, prior to the release of ampicillin for clinical use.
Compared with vancomycin, patients with ABSSSI treated with ceftaroline fosamil had significantly shorter length of hospital stay.
Researchers believe implementation of treatment guidelines for children with sickle cell disease with acute chest syndrome may decrease hospital readmission rates.
The recurrence of cellulitus can be prevented by antibiotic prophylaxis.
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