antibiotics

Fluoroquinolone Use May Increase Risk for Aortic Aneurysm and Dissection

Fluoroquinolone Use May Increase Risk for Aortic Aneurysm and Dissection

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Additional studies are needed to investigate whether there are differences between individual fluoroquinolones with respect to the risk for aortic aneurysm.

It Costs $2.2 Billion a Year to Treat Antibiotic Resistance

It Costs $2.2 Billion a Year to Treat Antibiotic Resistance

The need for innovative new infection prevention programs, antibiotics, and vaccines to prevent and treat antibiotic-resistant infections is an international priority.

Novel Drug Combinations, Dosing Strategies Needed for <i>E faecalis</i> Bloodstream Infections

Novel Drug Combinations, Dosing Strategies Needed for E faecalis Bloodstream Infections

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Review highlights available treatment options and their limitations and provides direction for investigation of future novel combination therapies to further aid in the treatment of Enterococcus faecalis infective endocarditis.

CDC: Aggressive Action Needed to Contain Antibiotic Resistance

CDC: Aggressive Action Needed to Contain Antibiotic Resistance

Early aggressive action should be taken to prevent the spread of bacteria harboring unusual resistance genes.

Antibiotics, Acid-Suppressive Medications Tied to Allergic Disease

Antibiotics, Acid-Suppressive Medications Tied to Allergic Disease

The use of acid-suppressive medications and antibiotics during the first 6 months of infancy is tied to subsequent development of allergic disease.

2013 to 2016 Saw No Change in Antibiotic Prescribing Practices

2013 to 2016 Saw No Change in Antibiotic Prescribing Practices

Results suggest that inappropriate prescribing of antibiotics remains widespread, despite the concurrent release of several guideline-based best practices intended to reduce inappropriate antibiotic consumption.

Role of Vaccines in the Fight Against Antimicrobial Resistance

Role of Vaccines in the Fight Against Antimicrobial Resistance

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The potential role of vaccinations in combatting antimicrobial resistance (AMR) is currently undervalued. The distribution and development of new vaccines should be priorities in efforts to address the AMR crisis.

Firvanq Availability Replaces Need for Compounded Oral Vancomycin Solution

Firvanq Availability Replaces Need for Compounded Oral Vancomycin Solution

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FIRVANQ is commercially available in 25 and 50 mg/mL strengths in convenient 150 mL and 300 mL sizes.

<i>H pylori</i> Treatment Tied to Lower Metachronous Gastric Cancer Risk

H pylori Treatment Tied to Lower Metachronous Gastric Cancer Risk

Helicobacter pylori treatment is associated with a reduced rate of metachronous gastric cancer.

Brucellosis Treatment: Rifampicin vs Streptomycin

Brucellosis Treatment: Rifampicin vs Streptomycin

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The findings of this study indicated that rifampicin therapy significantly increased the risk of overall failure and relapse compared with streptomycin.

Lower Antibiotic Prescribing Rates Linked to Integrative Medicine Training

Lower Antibiotic Prescribing Rates Linked to Integrative Medicine Training

Additional treatment strategies for common primary care infections used by integrative medicine general practitioners should be explored to see if they could be used to assist in the fight against antimicrobial resistance.

Adjunctive Antibiotic Therapy Yields Modest Benefit in Uncomplicated Skin Abscesses

Adjunctive Antibiotic Therapy Yields Modest Benefit in Uncomplicated Skin Abscesses

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Trimethoprim and sulfamethoxazole or clindamycin confer a modest benefit for several important outcomes, but this is offset by a similar risk for adverse effects.

Treatment for MRSA Complicated Bacteremia and Infective Endocarditis

Treatment for MRSA Complicated Bacteremia and Infective Endocarditis

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Further studies are warranted to assess the efficacy and safety of fosfomycin plus imipenem against methicillin-resistant Staphylococcus aureus complicated infections.

Antibiotic Rotation in ICU Does Not Reduce Prevalence of Antibiotic-Resistant Bacteria

Antibiotic Rotation in ICU Does Not Reduce Prevalence of Antibiotic-Resistant Bacteria

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Findings from the study did not provide evidence that antibiotic mixing, compared with antibiotic cycling with 6-week cycling periods reduced the prevalence of carriage with antibiotic-resistant, Gram-negative bacteria in the ICU.

Effectiveness of Meropenem-Vaborbactam for Complicated UTI Treatment

Effectiveness of Meropenem-Vaborbactam for Complicated UTI Treatment

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Evaluating treatment with meropenem/vaborbactam to piperacillin-tazobactam in patients with complicated UTIs.

FDA: Clarithromycin May Increase Long-Term Risk for Heart Problems, Death

FDA: Clarithromycin May Increase Long-Term Risk for Heart Problems, Death

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The recommendation was made after the FDA reviewed the results of a 10-year follow-up of the CLARICOR trial, which investigated the effects of clarithromycin in patients with stable coronary heart disease.

Characteristics Associated With Inappropriate Antibiotic Prescribing

Characteristics Associated With Inappropriate Antibiotic Prescribing

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Investigators identified patient, provider, and practice characteristics associated with antibiotic prescribing in an attempt to determine factors contributing to inappropriate antimicrobial use.

Antibiotic Prescribing Habits for UTI in Pregnant Women

Antibiotic Prescribing Habits for UTI in Pregnant Women

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For pregnant women in their first trimester, a 2011 Committee Opinion from the ACOG recommended that sulfonamides and nitrofurantoin may be prescribed only if other antimicrobial therapies are deemed clinically inappropriate.

Inappropriate Antibiotic Treatment Tied to Patient, Provider Characteristics

Inappropriate Antibiotic Treatment Tied to Patient, Provider Characteristics

Patient, practice, and provider characteristics are associated with inappropriate antimicrobial prescribing in the outpatient setting.

Trends of <i>S pneumoniae, H influenzae</i> Antibiotic Resistance in Children

Trends of S pneumoniae, H influenzae Antibiotic Resistance in Children

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Study analyzed the trends of nasopharyngeal carriage and antibiotic resistance of Streptococcus pneumoniae, Haemophilus influenza, and Moraxella catarrhalis isolated from young children with acute otitis media during a 16-year period.

Iclaprim Comparable With Vancomycin for Gram-Positive Acute Bacterial Skin Infections

Iclaprim Comparable With Vancomycin for Gram-Positive Acute Bacterial Skin Infections

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Iclaprim was noninferior to vancomycin with respect to the early clinical response at an early time point in the treatment of ABSSSI caused or suspected to be caused by gram-positive organisms.

Long-Term Macrolide Use Increases Risk of Resistant <i>P acnes</i>

Long-Term Macrolide Use Increases Risk of Resistant P acnes

Long-term oral macrolide administration may increase macrolide-resistant Propionibacterium acnes.

CDC: New Data Show Progress in Combating Antibiotic Resistance

CDC: New Data Show Progress in Combating Antibiotic Resistance

The CDC has released new data in its Antibiotic Resistance Investment Map on the progress in combating antibiotic resistance.

Alternative Therapeutics for Mild Infections May Help to Retain Antibiotic Efficacy

Alternative Therapeutics for Mild Infections May Help to Retain Antibiotic Efficacy

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Developing alternative, non-antibiotic treatments for certain "self-limiting infections" may help preserve the effectiveness of antibiotics.

New Immunotherapy Approach Shows Promise in Fight Against Antibiotic Resistance

New Immunotherapy Approach Shows Promise in Fight Against Antibiotic Resistance

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A new immunotherapy approach has shown promise in it's first-in-human trial for antibiotic-resistant bacteria.

Acute RTI in Children: Broad- vs Narrow-Spectrum Antibiotics

Acute RTI in Children: Broad- vs Narrow-Spectrum Antibiotics

Broad-spectrum antibiotics are not associated with better clinical or patient-centered outcomes compared with narrow-spectrum antibiotics in pediatric acute RTI.

Genome Sequencing Identifies Early Ampicillin Resistance

Genome Sequencing Identifies Early Ampicillin Resistance

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Using whole-genome sequencing, investigators determined that genetically different plasmids from antibiotic-resistant strains emerged in Salmonella enterica serotype Typhimurium in the late 1950s, prior to the release of ampicillin for clinical use.

Ceftaroline Fosamil Associated With Shorter ABSSSI-Related Hospital Stay

Ceftaroline Fosamil Associated With Shorter ABSSSI-Related Hospital Stay

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Compared with vancomycin, patients with ABSSSI treated with ceftaroline fosamil had significantly shorter length of hospital stay.

Guideline-Adherent Antibiotics Decrease Readmission for Acute Chest Syndrome

Guideline-Adherent Antibiotics Decrease Readmission for Acute Chest Syndrome

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Researchers believe implementation of treatment guidelines for children with sickle cell disease with acute chest syndrome may decrease hospital readmission rates.

Antibiotic Prophylaxis May Help Prevent Recurrent Cellulitis

Antibiotic Prophylaxis May Help Prevent Recurrent Cellulitis

The recurrence of cellulitus can be prevented by antibiotic prophylaxis.

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