Nearly all isolates from infants with botulism in Californian are susceptible to most clinically used antibiotics.
Cefiderocol was noninferior to imipenem-cilastatin in patients with complicated UTI who were at risk for multidrug-resistant infections.
A transient resistance to rifampin may emerge in patients after taking rifaximin.
Poor clinical outcomes linked to extended spectrum cephalosporin-resistant Enterobacteriaceae.
Despite notable advances in medical care, infections due to Pseudomonas aeruginosa remain problematic and are a major public health concern.
Resistance of gram negative bacteria to some cephalosporins has emerged as a significant threat over the last few decades as a results of ESBL enzymes.
Patients with Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae infections have multisystem disease and exposure to carbapenems and aminoglycosides.
For patients with Escherichia coli or Klebsiella pneumoniae bloodstream infections and ceftriaxone resistance, treatment with piperacillin-tazobactam compared with meropenem did not result in a non-inferior 30-day mortality.
Previous antibiotic use and mechanical invasive ventilation were risk factors for multidrug-resistant pathogens in hospital-associated or ventilator-associated pneumonia.
New data suggest an association between general practitioners' prescribing habits for urinary tract infections and UTI-related E coli bacteremia incidence.
Many antibiotic adverse drug events led to emergency department visits, particularly among young children, highlighting a need for better communication regarding the risks of overprescribing.
Higher minimum inhibitory concentration values of isoniazid or rifampin are associated with a greater risk of relapse in drug-susceptible tuberculosis than lower MICs.
As infections from drug-resistant microbes continue to rise, the development of new antibiotics has declined since the golden age of antibiotic discovery in the mid-20th century.
Neil Clancy, MD, from the VA Pittsburgh Health Care System, shares highlights from ASM Microbe 2018.
The frequency of relapse-free cure from multidrug-resistant tuberculosis is higher than previously anticipated.
Antimicrobial agents ceftazidime/avibactam and amikacin provided the best overall coverage against Gram-negative organisms isolated from patients with pneumonia in the ICU.
Nonsusceptibility to first-line antibiotics is associated with decreased survival in gram-negative bloodstream infections.
Researchers performed a cross-sectional study that included multiple year pooled data (2003 to 2011) from the National Ambulatory Medical Care Survey and the National Hospital Ambulatory Medical Care Survey.
The resistance of Helicobacter pylori to antibiotics is increasing worldwide, with primary and secondary resistance to clarithromycin, metronidazole, and levofloxacin reaching levels higher than 15%.
Some types of bacteria are developing tolerance of alcohol-based hand sanitizers used in hospitals.
Approximately 6% of all patients presenting at an emergency department during a one year period with a UTI were diagnosed with an ESBL-producing Enterobacteriaceae infection.
Extended-spectrum β-lactamase-producing Enterobacteriaceae in urine or feces is a substantial risk factor for subsequent EPE-bloodstream infection.
The majority of mismatched prescribed antibiotics for suspected UTI at an urgent care clinic among patients 70+ years old or with diabetes or urinary catheterization is likely the result of the multidrug-resistant H30 subclone of Escherichia coli ST131.
A new multi-drug resistant clone of Escherichia coli — ST1193 — has emerged in multiple US cities.
Ceftazidime/avibactam could be a suitable alternative to carbapenem-based regimens for certain serious Gram-negative infections.
Communities randomly assigned to less frequent antibiotic use had significantly lower prevalence of genetic antibiotic resistance determinants.
Procalcitonin-guided therapy did not reduce the number of antibiotic prescriptions among patients presenting to the ED with fever.
A study was conducted with a goal of developing a set of generic quality indicators for the safe and appropriate use of antibiotic agents.
Between 1999 and 2012, Acinetobacter baumannii antibiotic resistance increased in children.
Time to optimal antimicrobial therapy for positive blood cultures was assessed in a pediatric population.
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