Amit Akirov, MD, Author at Infectious Disease Advisor

Risk of stroke after herpes zoster in patients with autoimmune diseases

How Can Herpes Zoster Events Be Managed in Patients With RA and PsA Receiving Tofacitinib?

By

Amit Akirov, MD

January 14, 2022

Researchers evaluated the management of herpes zoster in patients with rheumatoid arthritis and psoriatic arthritis receiving tofacitinib treatment.

General Infectious Disease

Cabozantinib Shows Promise for Renal Cell Carcinoma With Brain Metastases

By

Amit Akirov, MD

December 2, 2021

The researchers sought to assess the safety and efficacy of cabozantinib to treat brain metastases in patients with metastatic renal cell carcinoma.

COVID19

A Shared Genetic Link Between Alzheimer Disease and Severe COVID-19

By

Amit Akirov, MD

November 22, 2021

In an effort to further investigate the link between OAS1 gene and AD, researchers sequenced genetic data from a cohort of patients with sporadic AD and those without.

General Infectious Disease

Influenza Infection Linked to Long-Term Increased Risk for Parkinson Disease

By

Amit Akirov, MD

November 18, 2021

Researchers sought to examine whether prior influenza or other infections are associated with Parkinson disease more than 10 years after infection.

COVID19

Anti-CD20 Therapy for Immune-Mediated Diseases Linked to Increased Mortality Risk in COVID-19

By

Amit Akirov, MD

November 15, 2021

Researchers examined whether treatment with CD20 inhibitors resulted in worse COVID-19 outcomes among patients with immune-mediated diseases.

A stroke is the most frequent neurologic complication of APS, and produces the most serious consequences.4 They can occur in any vascular region of the brain, and women are more likely to be affected than men. Patients who are APL-positive also tend to be younger compared with other patients with stroke who are APL-negative, with at least 20% of these strokes occurring in people <45 years. People who have APS secondary to SLE may be at higher risk for stroke.6 The risk for recurrence in primary APS may be higher, but this is not well established.4,5

Practice Management

Racial and Ethnic Disparities in Stroke Thrombolysis Use Are Declining

By

Amit Akirov, MD

November 11, 2021

Researchers analyzed the temporal trend in racial and ethnic differences in the use of intravenous thrombolysis after stroke between 2009 and 2018 in a representative sample of adults in the US.

COVID19

T-Cell and Humoral Response to SARS-CoV-2 Vaccine in Patients With MS on Ocrelizumab

By

Amit Akirov, MD

October 15, 2021

Researchers sought to determine the T-cell and antibody response to the SARS-CoV-2 vaccine in patients with multiple sclerosis treated with ocrelizumab, compared with healthy individuals.

COVID19

The Effect of MS Treatments on SARS-CoV-2 Vaccines and the Humoral Response

By

Amit Akirov, MD

October 13, 2021

Researchers determined the impact of other disease-modifying treatments in multiple sclerosis and the effect of delaying anti-CD20 infusion on the humoral response to COVID-19 vaccines.

COVID19

Study Reveals Histopathologic Findings in the Muscle and Nerve in Patients With Severe COVID-19

By

Amit Akirov, MD

September 16, 2021

Researchers analyzed the autopsies of patients who died from COVID-19 to understand the pathophysiology of COVID-19-related myopathy.

Patient in hospital wearing mask receiving IV medicine

COVID19

Does Anakinra Have a Role in the Treatment of Severe COVID-19?

By

Amit Akirov, MD

September 14, 2021

Authors of a commentary assessed the role of IL-1 receptor antagonism, specifically anakinra, in the treatment of patients with severe COVID-19.

Amit Akirov, MD

All articles by Amit Akirov, MD

How Can Herpes Zoster Events Be Managed in Patients With RA and PsA Receiving Tofacitinib?

Cabozantinib Shows Promise for Renal Cell Carcinoma With Brain Metastases

A Shared Genetic Link Between Alzheimer Disease and Severe COVID-19

Influenza Infection Linked to Long-Term Increased Risk for Parkinson Disease

Anti-CD20 Therapy for Immune-Mediated Diseases Linked to Increased Mortality Risk in COVID-19

Racial and Ethnic Disparities in Stroke Thrombolysis Use Are Declining

T-Cell and Humoral Response to SARS-CoV-2 Vaccine in Patients With MS on Ocrelizumab

The Effect of MS Treatments on SARS-CoV-2 Vaccines and the Humoral Response

Study Reveals Histopathologic Findings in the Muscle and Nerve in Patients With Severe COVID-19

Does Anakinra Have a Role in the Treatment of Severe COVID-19?

Outcomes Similar With CPAP, Oxygen Therapy for Severe COVID-19