Clinical Benefit Observed With Colchicine in Hospitalized COVID-19 Patients
The open-label, prospective study (GRECCO-19) assessed the effect of treatment with low-dose colchicine on cardiac and inflammatory biomarkers as well as clinical outcomes.
All articles by Cassandra Pardini, PharmD
CDC: Penicillin-, Ciprofloxacin-Resistant Meningococci Detected in US
The CDC has reported observing a significant increase in the number of meningococcal disease cases with isolates containing a blaROB-1 β-lactamase enzyme gene, conferring resistance to penicillin antibiotics and, in some cases, ciprofloxacin as well.
Adenovirus Type 5 Vectored COVID-19 Vaccine Tolerable, Immunogenic in Phase 1 Study
A total of 108 healthy adult volunteers 18 to 60 years old (mean age, 36.3 years old) with no history of COVID-19 infection were enrolled in the study.
Immune Globulin Therapy Linked to Heart Function Recovery in COVID-Related Multisystem Inflammatory Syndrome
The use of immune globulin therapy appears to benefit children who experience acute heart failure caused by coronavirus disease 2019 (COVID-19)-related multisystem inflammatory syndrome, according to the findings of a case series recently published in Circulation.
Antihypertensive Medication Use Not Linked to Risk for COVID-19
“There was no association between any single medication class and an increased likelihood of a positive test,” the study authors reported. They added, “None of the medications examined was associated with a substantial increase in the risk of severe illness among patients who tested positive.”
Successful Management of Severe COVID-19 in Otherwise Healthy Pediatric Patient
Sustained improvement was noted after the administration of tocilizumab, an interleukin-6 antagonist.
NIH Treatment Guidelines for COVID-19 Released
Recommendations on the management of coronavirus disease 2019 (COVID-19) were recently released by the National Institutes of Health (NIH) to help guide clinicians caring for patients with COVID-19.
UTI Recurrence in Pediatric Patients: Antibiotic Treatment Duration Examined
In pediatric patients, the duration of antibiotic treatment for uncomplicated UTI was not significantly associated with UTI recurrence.
Several Antibiotics Linked to Hypoglycemia Despite Accounting for Glucose-Lowering Medications
Several antibiotics were found to be associated with hypoglycemia even after accounting for concomitant use of glucose-lowering medications.
Nebulized Normal Saline Evaluated for Acute Viral Bronchiolitis
Nebulized normal saline, which is often used as a placebo in clinical trials evaluating therapies for acute viral bronchiolitis, may be an active treatment for this condition.
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