Treatment Regimens and Recommendations for HIV/HCV Coinfection
Experts discuss the management of drug-drug interactions in patients receiving treatment for HIV and HCV coinfection.
All articles by Crystal Wong, MD
DAAs Effective for HCV in Patients With Thalassemia
Researchers compared the safety and efficacy of sofosbuvir plus ledipasvir vs pegylated interferon and ribavirin for 12 weeks in patients with thalassemia major and hepatitis C virus genotype 1 or 4.
New Scoring System Predicts In-Hospital Mortality in Critically Ill Children With Sepsis
A new organ dysfunction scoring system that predicts in-hospital mortality was validated in critically ill children admitted to the pediatric intensive care unit.
Azithromycin Prevents COPD Exacerbations in H pylori Seropositive Patients
Azithromycin is more likely to reduce exacerbations of COPD among patients with antibodies against Helicobacter pylori.
New WHO Guidelines for Hepatitis B Virus Vaccine
The World Health Organization published a position paper with updated recommendations on the use of the hepatitis B vaccine regarding target groups, immunization schedules, and storage and distribution.
Update on Safe, Effective Treatments for Latent Tuberculosis Infection
A recent update of a meta-analysis evaluating treatments for latent tuberculosis infection found that several regimens, including those with a low pill burden and short duration, were safe and effective.
Mycoplasma genitalium: Challenges in Diagnosis and Treatment
While Mycoplasma genitalium is emerging as one of the most common causes of sexually transmitted infections, and is often underrecognized and treated with ineffective antibiotics.
Genetic Marker Correlates With Severe Influenza Outcomes
A newly identified genetic polymorphism was associated with increased rates of mortality and severe clinical outcomes from influenza infection and lower levels of resident lung CD8+ T cells, particularly in individuals of European descent.
Hepatitis C Virus Infection and Cardiovascular Disease Risk
Epidemiological data demonstrate a link between HCV infection and cardiovascular disease, whereas treatment studies suggest viral eradication may lower the risk for cardiovascular morbidity and mortality.
New WHO Guidelines for Managing Pretreatment HIV Drug Resistance
New WHO guidelines address the issue of how to manage pretreatment human immunodeficiency virus drug resistance (HIVDR) in countries where the prevalence of HIVDR is 10% or higher.
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