Study provides a portrait of wild-type AAV infection in the liver with an identification of molecular forms, viral genotypes, viral integrations, and helper virus relationship and with AAV insertions positive selected during HCC development on noncirrhotic liver, which challenges the concept of AAV as nonpathogenic.
The Hologic Panther Fusion® Open Access™ system, a successfully developed and validated multiplex PCR, laboratory-developed test performed comparably to or better than a commercial reference assay.
Two studies on hepatitis A and hepatitis B vaccination highlight opportunities to improve coverage of ≥2 doses of hepatitis A vaccine in children and hepatitis B vaccine series completion in adults.
Bloodstream infections are common in patients who have received a solid organ transplants.
HIV treatment and virologic failure, and sustained viral response at week 12 or 24 were not different among patients who did or did not undergo a switch in their antiretroviral therapy regimen prior to DAA treatment.
Hepatitis E seropositivity is higher in older adults and may represent an increased exposure risk over time; in contrast, the opioid crisis has caused a demographic shift in hepatitis C infection, which is now a predominately millennial disease.
Data on a prefusion respiratory syncytial virus fusion glycoprotein subunit vaccine antigen strongly support this vaccine’s development as a method of preventing the virus in infants by immunizing pregnant women.
Among individuals with acute myelogenous leukemia (AML), carbapenem-nonsusceptible gram-negative bacteremia (GNB) is associated with worse outcomes than carbapenem-susceptible GNB.
Cardiac implantable electronic device-related infective endocarditis is diagnosed in a third of patients with implantable device related infections.
A new scoring system for Drug Resistance in Pneumonia (DRIP) has demonstrated efficacy in improving pneumonia-related prescription trends, including a significant drop in broad-spectrum antibiotic prescriptions.
