John Browning, Author at Infectious Disease Advisor

John Browning

All articles by John Browning

Chronic Mucocutaneous Candidiasis (candidiasis of unspecified site), unspecified disorder of immune mechanism)

Are You Confident of the Diagnosis? Chronic mucocutaneous candidiasis (CMC) is a heterogeneous group of disorders in which persistent or recurrent fungal infections of nail beds, skin, and mucosal surfaces occur in primary or secondary immunodeficiencies. It presents as recurring infections of the skin and mucous membranes with yeasts, mostly Candida albicans. The different CMC…

Aplasia Cutis Congenita (congenital skin anomaly)

Are You Confident of the Diagnosis? Aplasia cutis congenita (ACC) refers to any case in which there is congenital absence of skin at birth. The incidence is estimated to be between 0.5 and 1 in 10,000 newborns. It may be due to any number of causes, ranging from epidermolysis bullosa to incomplete closure of the…

Candidiasis (Candidosis)

Candidiasis, candidosis, Are You Confident of the Diagnosis? What you should be alert for in the history Candida albicans and other Candida species are fungal infections commonly involved in human disease. Clinical disease may be as varied as mucocutaneous infections, chronic mucocutaneous candidiasis, candidemia and sepsis, and invasive infections of internal organs. The mortality rate…

Adams-Oliver syndrome

Adams-Oliver Syndrome (AOS) 757.39 (congenital skin anomaly) Are You Confident of the Diagnosis? Adams-Oliver syndrome (AOS) is a rare congenital disorder characterized by aplasia cutis congenita (ACC) of the vertex scalp, limb defects, and cutis marmorata telangiectatica congenita (CMTC) (Figure 1 , Figure 2 , Figure 3 , Figure 4 ). It was first described…

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