Are You Confident of the Diagnosis? Intrahepatic cholestasis of pregnancy (ICP) is defined by: (1) generalized pruritus, with or without jaundice, with no history of exposure to hepatitis or hepatotoxic drugs, (2) the absence of primary lesions on the skin (Figure 1), (3) biochemical abnormalities consistent with cholestasis, (4) disappearance of signs and symptoms following…
Are You Confident of the Diagnosis? Pruriticurticarial papules and plaques of pregnancy (PUPPP) tend to occur during the later third trimester or the immediate postpartum period. Rarely, they may be seen any time after the first trimester. PUPPP tends to be more common in primiparous women, women with large-for-date babies and those patients carrying twins…
Are You Confident of the Diagnosis? Prurigo of pregnancy (PP) is the most contested classification of the pregnancy dermatoses. The features of this disorder have historically been ill-defined. Its current classification includes papular dermatitis and pruritic folliculitis, which are considered by some to be separate disease processes. It is postulated that prurigo of pregnancy is…
Are You Confident of the Diagnosis? What you should be alert for in the history Gestational pemphigoid classically presents during the second or third trimester, but 25% of cases have been reported to occur during the immediate postpartum period. It typically presents with the sudden onset of severe pruritus, followed by urticarial lesions on the…
