Sandeep Khot, Author at Infectious Disease Advisor

Sandeep Khot

All articles by Sandeep Khot

Neuroleptic malignant syndrome

Neuroleptic Malignant Syndrome I. What every physician needs to know. Neuroleptic malignant syndrome (NMS) is a rare, potentially fatal complication of treatment with dopamine antagonists (e.g., neuroleptics such as haloperidol) or less commonly acute withdrawal of dopamine agonists (e.g., Parkinson’s medications such as carbidopa-levodopa). The classic clinical presentation is a tetrad of fever, muscle rigidity,…

Primary angiitis of the central nervous system

Primary angiitis of the central nervous system I. Problem/Condition. Cerebral vasculitis is a rare and enigmatic disorder defined by inflammation of the blood vessels of the leptomeninges, brain and/or spinal cord. Inflammation of the cerebral vessels leads to narrowing, occlusion and thrombosis which can then result in ischemia and necrosis. This inflammatory process is typically…

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