Talia Kahn

All articles by Talia Kahn

Adrenal cancer

I. What every physician needs to know Though adrenal tumors are relatively common in the general population, adrenocortical carcinoma (ACC) is a rare malignancy with a relatively poor prognosis. The pathogenesis of ACC is not well understood. Mutations which inactivate the TP53 tumor suppressor gene or lead to over expression of IGF-II are frequently seen…

Adrenal adenoma

I. What every physician needs to know Each adrenal gland (also known as suprarenal gland) is essentially two separate and distinct endocrine glands – the cortex and the medulla. The adrenal cortex consists of three concentric zones. The outer zone is the glomerulosa, which secretes mineralocorticoid; the intermediate zone is the fasciculata, which secretes glucocorticoids,…

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