Needle and syringe programs are a highly effective, low-cost intervention to reduce HCV transmission.
All articles by Virginia Schad, PharmD
Researchers found that to achieve the WHO goal for worldwide elimination of HBV, patients at risk for spontaneous HBsAg loss should be included in trials for treatments that are outside of current treatment criteria.
Treatment of HCV with grazoprevir plus elbasvir is effective in the acute phase of infection and therefore should be used in patients at high risk for HCV transmission.
Researchers found dose-related reductions in serum HBV DNA, RNA, and anti-HBV levels were achieved with the combined use of NVR 3-77 and pegIFN.
Patients with chronic HCV and renal dysfunction may be a difficult-to-treat population when considering ribavirin combination regimens.
Periodic monitoring of viral load in children with HIV will allow early identification of virologic failures and regimen change, thus avoiding accumulation of resistant strains and treatment failures.
Community-level interventions targeting food distress may improve the health of people living with HIV and reduce the risk for forward transmission.
Viral control is more prevalent in infected partners in HIV-serodiscordant couples compared with PLWHIV who are not in a similar relationship.
Interferon alfa may decrease chronic HCV, but high-quality randomized trials are needed.
Researchers demonstrated for the first time that the rs3077-T allele is associated with spontaneous hepatitis B virus seroclearance in a Caucasian population, a finding that has previously only been made in Asian populations.
Early treatment, especially before development of cirrhosis, significantly decreases morbidity and mortality associated with HCV infection.
Further efforts are needed to educate and prepare healthcare providers to prescribe PrEP and manage patients on PrEP to reduce the risk for acquiring HIV.
Both hepatitis C virus infection and alcohol-related diagnoses remained major risk factors for medical intensive care unit admission between 2010 and 2014, according to data from a national Veterans Affairs electronic health record system.
A new integrase inhibitors resistance pathway in HIV-2 infected patients has been identified rendering isolates that are highly resistant.
Early diagnosis of HIV is associated with higher viral loads compared to when individuals are diagnosed in later stages of the disease.
Findings show the safety of dapivirine use in early pregnancy and provide support for additional studies of the dapivirine ring at different gestational ages in order to confirm the safety of dapivirine ring use throughout pregnancy.
Findings suggest that the degree of liver fibrosis regression from direct-acting antiviral therapy is overestimated by transient elastography compared to liver biopsy.
Introducing certified health educator-driven routine opt-out rapid HIV screening and system-level modifications significantly increased HIV screening rates, rapid tests, and result receipt in youth.
Chronic hepatitis B virus infection may actually lower the risk for developing dyslipidemia.
Phase 4 study confirmed good safety profile for 2 doses of an inactivated hepatitis A vaccine (Avaxim® 80U Pediatric) in children age 12 months to 15 years in China.
Higher fibroblast growth factor-23 concentrations are independently associated with incident frailty among HIV-infected and -uninfected men, particularly among blacks.
Results provide an evidence base for effective pediatric advance care planning in pediatric, hospital-based HIV clinics to achieve quality improvement.
Pre-exposure prophylaxis is a highly effective element of the combination prevention approach in men who have sex with men.
Lamivudine is a low-cost, safe, and effective prophylaxis for white patients with non-Hodgkin lymphoma and resolved HBV infection undergoing rituximab-based chemotherapy.
Hispanic/Latina women with HIV infection receiving medical care face greater socioeconomic and language-related challenges than their male counterparts.
Significant fibrosis and cirrhosis can be predicted with high accuracy using noncommercial serum markers or transient elastography in hepatitis C virus.
Dedicated resources are needed to optimize HIV care for people living with HIV while they are in prison and link them to care following release.
A new nucleotide analog is a pangenotypic HCV nonstructural protein 5B inhibitor that is well tolerated when administered in single and multiple doses.
Low rates of HBsAg seroclearance were found in untreated and treated patients with chronic hepatitis B infection.
Investigators aimed to determine rates and predictors of cirrhosis and cirrhosis-related complications in patients with chronic hepatitis B infection.