Cardiovascular Disease

Elevated PCSK9 Levels Associated With Coronary Endothelial Dysfunction in PLWHIV

Elevated PCSK9 Levels Associated With Coronary Endothelial Dysfunction in PLWHIV

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Increased proprotein convertase subtilisin/kexin type 9 (PCSK9) levels in people with HIV may be related to abnormal coronary endothelial function.

HCV Treatment Linked to Reduced Risk of Incident CVD Events

HCV Treatment Linked to Reduced Risk of Incident CVD Events

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ERCHIVES (Electronically Retrieved Cohort of HCV Infected Veterans) was utilized to identify all patients who received HCV treatment for at least 7 weeks as well as a propensity-score matched group who did not receive treatment.

Variable Period of Risk for Myocardial Infarction and Stroke Following Sepsis

Variable Period of Risk for Myocardial Infarction and Stroke Following Sepsis

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Patients recovering from sepsis had an elevated risk for myocardial infarction or stroke in the first 4 weeks after hospital discharge compared to the general population.

Statins Increase Risk for Medically Attended Acute Respiratory Illness

Statins Increase Risk for Medically Attended Acute Respiratory Illness

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Elderly patients who have been inoculated with the influenza vaccine and who also use a statin are at a greater risk for medically attended acute respiratory illness.

High-Risk HPV Infection Linked With Cardiovascular Disease in Women

High-Risk HPV Infection Linked With Cardiovascular Disease in Women

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Women with high-risk human papillomavirus are at higher risk for developing cardiovascular disease than women without high-risk HPV

Sustained Hepatitis C Treatment Associated With Lower Risk for Cardiovascular Events

Sustained Hepatitis C Treatment Associated With Lower Risk for Cardiovascular Events

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Treatment for hepatitis C is associated with a reduction in cardiovascular events.

Continued Noninferiority of Doravirine to Efavirenz at Week 96

Continued Noninferiority of Doravirine to Efavirenz at Week 96

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The week 96 results of the DRIVE-AHEAD phase 3 noninferiority trial support noninferiority of doravirine to efavirenz in treatment-naive adults with HIV-1.

Abacavir Linked to Increased Risk for Cardiovascular Disease in PLWHIV

Abacavir Linked to Increased Risk for Cardiovascular Disease in PLWHIV

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Exposure to abacavir is associated with an increased risk for cardiovascular disease in individuals infected with HIV.

Carotid Artery Atherosclerosis Is Associated With Mortality in Adults With HIV

Carotid Artery Atherosclerosis Is Associated With Mortality in Adults With HIV

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Carotid artery plaque was predictive of mortality, with differences observed by sex and HIV serostatus.

Switch to Dolutegravir Regimen Improves Lipid Profile in HIV+ Patients

Switch to Dolutegravir Regimen Improves Lipid Profile in HIV+ Patients

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Immediate and deferred switching from a boosted protease inhibitor to a dolutegravir regimen in HIV + patients is found to be highly efficacious.

Bilirubin Levels May Be Predictive of Cardiovascular Disease in HIV

Bilirubin Levels May Be Predictive of Cardiovascular Disease in HIV

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Bilirubin appeared to be inversely associated with cardiovascular disease in individuals with HIV enrolled in the Veterans Aging Cohort Study.

Increased Risk for Abdominal Obesity Found in People Living With HIV

Increased Risk for Abdominal Obesity Found in People Living With HIV

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The Copenhagen Co-morbidity in HIV Infection (COCOMO) study assessed the association between risk factors for cardiovascular disease and HIV infection.

Influenza Vaccination May Reduce Mortality Risk in Heart Failure

Influenza Vaccination May Reduce Mortality Risk in Heart Failure

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A meta-analysis sought to determine the effect of influenza vaccination on cardiac-related mortality in patients with heart failure.

Pneumonia: Inflammation Linked to Cardiovascular Complications

Pneumonia: Inflammation Linked to Cardiovascular Complications

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Community-acquired pneumonia and other acute infections can cause or exacerbate cardiovascular complications.

Myopericarditis Risk in Adults Following Live Viral Vaccination Rare

Myopericarditis Risk in Adults Following Live Viral Vaccination Rare

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Findings confirm that cardiovascular complications related to commonly-administered, live viral vaccination are rare in adults.

Hepatitis C Eradication With DAAs Improves Carotid Atherosclerosis

Hepatitis C Eradication With DAAs Improves Carotid Atherosclerosis

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HCV eradication by DAA improves carotid atherosclerosis in patients with advanced fibrosis and compensated cirrhosis.

ARDS Risk High After Cardiac Surgery During Influenza Season

ARDS Risk High After Cardiac Surgery During Influenza Season

Undergoing cardiac surgery during the influenza season is associated with increased risk of ARDS.

FDA: Clarithromycin May Increase Long-Term Risk for Heart Problems, Death

FDA: Clarithromycin May Increase Long-Term Risk for Heart Problems, Death

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The recommendation was made after the FDA reviewed the results of a 10-year follow-up of the CLARICOR trial, which investigated the effects of clarithromycin in patients with stable coronary heart disease.

Viral respiratory infections associated with increased risk of acute myocardial infarction

In a self-controlled case series, patients were observed to have increased incidence of hospital admissions for acute myocardial infarction within 7 days of respiratory virus detection.

Low Adherence to Guidelines for Cardiovascular Care in HIV

Low Adherence to Guidelines for Cardiovascular Care in HIV

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A new study sought to qualify the adherence to evidence-based cardiovascular care guidelines for patients living with HIV.

Pulmonary Artery Systolic Pressure Higher in HIV-Infected Individuals

Pulmonary Artery Systolic Pressure Higher in HIV-Infected Individuals

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HIV-infected people with unsuppressed HIV virus or low CD4 cell counts had a higher prevalence of increased pulmonary artery systolic pressure than uninfected people.

Carotid Plaque, Risk of Vascular Disease Events Higher in HIV

Carotid Plaque, Risk of Vascular Disease Events Higher in HIV

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Findings show that HIV status was associated with an increased rate of incidental carotid plaque, noncalcified plaque, and high-risk plaque.

Abacavir ART Does Not Increase Risk for Myocardial Infarction or CVD

Abacavir ART Does Not Increase Risk for Myocardial Infarction or CVD

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Abacavir-containing antiretroviral therapy does not appear to confer an increased risk for myocardial infarction or coronary artery disease.

Do Traditional Risk Factors for CVD Play Larger Role in HIV-Positive Premenopausal Women?

Do Traditional Risk Factors for CVD Play Larger Role in HIV-Positive Premenopausal Women?

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Traditional risk factors may incur a higher risk for CVD in HIV-positive premenopausal women than HIV infection itself.

Increased CVD Risk Persists for Years After Treatment for Sepsis or Pneumonia

Increased CVD Risk Persists for Years After Treatment for Sepsis or Pneumonia

Cardiovascular disease risks persist for years after sepsis or pneumonia.

Hepatitis C Virus Infection and Cardiovascular Disease Risk

Hepatitis C Virus Infection and Cardiovascular Disease Risk

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Epidemiological data demonstrate a link between HCV infection and cardiovascular disease, whereas treatment studies suggest viral eradication may lower the risk for cardiovascular morbidity and mortality.

Predicting Cardiovascular Outcomes in Liver Transplant Candidates

Predicting Cardiovascular Outcomes in Liver Transplant Candidates

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Dobutamine stress perfusion echocardiography can detect microvascular perfusion abnormalities that predict cardiovascular outcomes in candidates for liver transplantation.

Respiratory Infections May Trigger Acute Myocardial Infarction

Respiratory Infections May Trigger Acute Myocardial Infarction

Risk of acute myocardial infarction is 17 times higher after respiratory infection.

Pitavastatin Lowers Cholesterol More Effectively Than Pravastatin in HIV

Pitavastatin Lowers Cholesterol More Effectively Than Pravastatin in HIV

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Pitavastatin reduced low-density lipoprotein cholesterol to a greater extent than pravastatin with a similar safety profile in patients with HIV and dyslipidemia.

Does Use of Azithromycin Increase Risk of Ventricular Arrhythmia?

Does Use of Azithromycin Increase Risk of Ventricular Arrhythmia?

Patients who took azithromycin weren't any more likely to develop ventricular arrhythmia than those taking amoxicillin.

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