Covid 19 News & Insights

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COVID19 antibodies

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for the latest Covid-19 news, updates and clinical insights to better understand Covid-19’s impact on patient health.

Fluvoxamine May Reduce COVID-19 Hospitalizations and ED Visits

Fluvoxamine is safe for treating non-hospitalized patients with COVID-19 and may lead to a reduction in hospitalizations and fewer emergency department (ED) visits, according to a meta-analysis published in the Journal of Infection and Public Health. Fluvoxamine, a selective serotonin reuptake inhibitor which has been used for the treatment of depression, has an anti-inflammatory effect.…

Pfizer, BioNTech Submit EUA Request for Bivalent COVID-19 Vaccine in Younger Children

Pfizer and BioNTech have submitted an application to the Food and Drug Administration (FDA) requesting Emergency Use Authorization (EUA) of the Omicron BA.4/BA.5-adapted bivalent COVID-19 vaccine as the third 3-µg dose in the 3-dose primary series for children 6 months through 4 years of age. Due to the high level of respiratory illnesses currently circulating…

SGLT-2i Use Before COVID-19 May Reduce Adverse Outcomes in Patients With Diabetes

HealthDay News — For patients with diabetes subsequently diagnosed and hospitalized with COVID-19, use of a sodium-glucose cotransporter-2 inhibitor (SGLT-2i) before COVID-19 infection is associated with lower COVID-19-related adverse outcomes, according to a systematic review and network meta-analysis published online Dec. 6 in JAMA Network Open. Zheng Zhu, from the Shengli Clinical Medical College of Fujian…

GOUT-36 Rule Predicts Risk for Flares in Patients With Comorbid Gout and COVID-19

The GOUT-36 rule was found to predict gout flares, which occurred in 18% of patients with comorbid gout hospitalized for COVID-19 infection and an increased hospital stay by 3 days, according to study findings published in The Journal of Rheumatology. Researchers conducted a multicenter retrospective cohort study between March 2020 and December 2021 across 3…

Dynamically Updating Models Can Improve Prediction of COVID-19 Survival

HealthDay News — Dynamically updating models can improve prediction of 28-day survival in hospitalized COVID-19 patients, according to a study published online Nov. 10 in Nature Communications. Todd J. Levy, from the Feinstein Institutes for Medical Research at Northwell Health in Manhasset, New York, and colleagues developed a framework for continuously monitoring and updating prognostic models…

Does Tralokinumab Treatment in Atopic Dermatitis Affect COVID-19 and Vaccination?

Tralokinumab treatment in patients with moderate to severe atopic dermatitis (AD) does not produce new safety concerns and does not present evidence of SARS-CoV-2 vaccine reduced effectiveness, according to research letter findings published in the Journal of the American Medical Association Dermatology. Immunomodulatory drugs such as tralokinumab, an IgG4 monoclonal antibody that neutralizes interleukin 13,…

Maternal Antibodies Higher After COVID-19 Vaccination vs Infection In Pregnancy

COVID-19 vaccination during pregnancy is associated with increased concentrations of maternal immunoglobulin (Ig) G, cord blood IgG, and higher transfer ratio; however, maternal IgG concentrations decrease over time after both COVID-19 vaccination and infection. These study results were published in Clinical Infectious Diseases. Researchers conducted a prospective cohort study among women who were infected with…

Study Looks at Extent of Residual Lung Abnormalities After COVID-19 Hospitalization

HealthDay News — Residual lung abnormalities are estimated in up to about 11.7 percent of patients discharged following COVID-19-related hospitalization, according to a study published online Dec. 2 in the American Journal of Respiratory and Critical Care Medicine. Iain Stewart, Ph.D., from Imperial College London, and colleagues estimated the prevalence of residual lung abnormalities in people…

PTSD, Psychiatric Disorders Tied to Higher Risk for Severe COVID-19 Outcomes

HealthDay News — Veterans with posttraumatic stress disorder (PTSD) and other psychiatric disorders have a heightened risk for severe adverse outcomes with COVID-19, according to a study published online Nov. 22 in Translational Psychiatry. Kristen Nishimi, Ph.D., from the University of California in San Francisco, and colleagues used data from 228,367 U.S. Department of Veteran Affairs…

Molnupiravir May Be Effective Against COVID-19 in Vaccinated, Unvaccinated Adults

Molnupiravir may have antiviral activity against COVID-19 infection among both vaccinated and unvaccinated adults infected with a variety of SARS-CoV-2 variants, according to study findings published in the Lancet Infectious Diseases. Researchers conducted a randomized, double-blind, placebo-controlled, phase 2 trial between November 2020 and March 2022 across 5 sites in the United Kingdom. They evaluated…