Suppressing cytomegalovirus may improve the immune response to a T cell-dependent pneumococcal vaccination in patients experiencing ANCA-associated vasculitis.
Investigators retrospectively reviewed the patients' medical records and MRI images and assessed the associations between the MRI findings and neurologic outcomes, specifically neurodevelopmental achievement, epilepsy, and sensorineural hearing loss.
In this review, David C. Helfgott, MD, editorial advisory board member for Infectious Disease Advisor, focuses on infectious complications from the use of monoclonal antibodies for malignancy.
Findings provide an alternative explanation for virus acquisition and shedding in seroimumne pregnant women that contrasts with proposed mechanisms that argue that reactivation of persistent infection in seroimmune women leads to infection and virus shedding.
Investigators sought to determine the association between antiretroviral therapy and cytomegalovirus infection in individuals with HIV, as well as the potential impact of both on neurocognitive performance.
Middle-aged woman who received a heart transplant 1 year ago because of dilated cardiomyopathy now presents with mild fever and generalized weakness.
The FDA has approved letermovir for the treatment and prevention of cytomegalovirus.
Cytomeglovirus infection is associated with a range of diagnostic and treatment challenges and a relatively high transmission rate from the mother to the fetus.
Phase 3 study showed positive results for Merck's letermovir in prevention of CMV infection in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant.
An expert Q&A with Florian Kern, PhD, deputy director of research at Brighton and Sussex Medical School in the UK, who makes the case that cytomegalovirus is a major driver of cardiovascular disease in patients with rheumatoid arthritis.
Mortality in patients with rheumatic disease is associated with high cytomegalovirus titers.
Identifying optimal bronchoalveolar fluid CMV viral load threshold holds potential for diagnosing CMV pneumonia in immunocompromised patients.
Subclinical CMV replication during early infection of HIV associated with lower CD4/CD8 ratio during suppressive ART.
While universal screening for congenital CMV is more cost-effective than current standard of care, concerns about CMV screening remain.
A latent cytomegalovirus infection causes chronic infection phenotype in CD8+ cells.
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Infectious Disease Advisor Articles
- Predicative Factors for Relapse in Adult Bacterial Osteomyelitis
- Zika Vaccine Cost-Effective for Young Adults and Childbearing-Age Women
- Cefiderocol for the Treatment of Complicated Gram-Negative UTIs
- Stethoscope Cleaning Standards May Not Eliminate Bacterial Contamination
- Higher Viral Control in Women With HIV in Serodiscordant Relationships
- Antibiotic Use in Neonatal Settings in Need of Improvement
- Shorter Antibiotic Course Noninferior for Gram-Negative Bacteremia
- Rapid Antimicrobial Susceptibility Testing on Urine Directly Accelerates Results
- Antibiotics May Be Beneficial in Children With Prolonged Wet Cough
- Emergency Department Overcrowding Associated With Delayed Antibiotics in Patients With Sepsis
- HIV-Positivity Not Associated With Higher Household Influenza Transmission
- Bacteria Bystanders Play Important Role in Antibiotic Resistance Development
- Many New Cancer Patients Unaware of Their Hepatitis Status
- Worse Outcomes in Community-Acquired Pneumonia Linked to Higher FGF21 Levels
- Bacterial Pneumonia-Complicating Influenza: Risks, Morbidity, and Mortality