Diagnostic Testing

New HPV Screening Kit Allows Women to Test at Home

New HPV Screening Kit Allows Women to Test at Home

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To obtain a kit, patients must first answer a few medical history questions to determine if they are appropriate candidates for at-home testing.

Point-of-Care Testing Methods Compared for Influenza Detection

Point-of-Care Testing Methods Compared for Influenza Detection

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Study authors aimed to assess the clinical impact of a POC PCR test (the Cobas LIAT Influenza A/B assay) for the diagnosis of influenza.

Trial Results Affected by Heterogeneous CAP Inclusion Criteria

Trial Results Affected by Heterogeneous CAP Inclusion Criteria

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The diagnostic criteria for community acquired pneumonia within randomized controlled trials are highly heterogeneous.

HIV/STI Counseling and Testing for Patients on PrEP

HIV/STI Counseling and Testing for Patients on PrEP

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Further efforts are needed to educate and prepare healthcare providers to prescribe PrEP and manage patients on PrEP to reduce the risk for acquiring HIV.

i-STAT Technology May Improve Detection of <i>Burkholderia pseudomallei</i>

i-STAT Technology May Improve Detection of Burkholderia pseudomallei

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The i-STAT assay may detect the Burkholderia pseudomallei capsule and the purified anticapsular polysaccharide more accurately than standard methods.

Partner-Delivered HIV Self-Testing Can Up Linkage to Care

Partner-Delivered HIV Self-Testing Can Up Linkage to Care

HIVST and reminder phone calls or financial incentives increase HIV testing, care.

Rapid Antimicrobial Susceptibility Testing on Urine Directly Accelerates Results

Rapid Antimicrobial Susceptibility Testing on Urine Directly Accelerates Results

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Rapid antimicrobial susceptibility testing by disc diffusion performed directly on urine samples shows less delay than standard method for diagnosis of UTI.

Mail-Based HPV Self-Tests in Appalachian Ohio Show Promise

Mail-Based HPV Self-Tests in Appalachian Ohio Show Promise

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Testing for human papillomavirus through a mail-based self-test holds promise as a means to reach underscreened women.

Not All Patients Prefer Delivery of STI/HIV Screening Results Via SMS

Not All Patients Prefer Delivery of STI/HIV Screening Results Via SMS

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The delivery of STI/HIV screening results via SMS is well accepted but does not suit all patients.

Influenza Point-of-Care Tests Influence Patient Outcomes

Influenza Point-of-Care Tests Influence Patient Outcomes

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Point-of-care testing for influenza has a role persons with influenza-like illnesses, particularly in emergency departments and during influenza epidemics, but tests are not a substitute for clinical assessment.

High Sensitivity, Specificity for Chlamydia Point-of-Care Test

High Sensitivity, Specificity for Chlamydia Point-of-Care Test

Polymerase chain reaction test has high sensitivity and specificity for vaginal swab samples.

Quick New Ebola Test Approved by FDA

Quick New Ebola Test Approved by FDA

A fast, single-use fingerstick test for infection with the Ebola virus has been approved by the FDA.

A Model to Predict Mortality and Disease Outcomes in C difficile Infection

A Model to Predict Mortality and Disease Outcomes in C difficile Infection

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This study presents a simple, widely available and inexpensive model for predicting C difficile infection severity and mortality to identify patients at risk at admission to the ED.

Viral Suppression in Children on ART Identified Via Quantitative HIV Antibody Levels

Viral Suppression in Children on ART Identified Via Quantitative HIV Antibody Levels

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For children receiving , HIV-1-specific antibody levels can be useful markers for measuring viral suppression or for low residual cell-associated HIV-1 DNA levels.

Evidence of Zika Congenital Syndrome in Pre-Term Newborn

Evidence of Zika Congenital Syndrome in Pre-Term Newborn

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Case-study demonstrates that epithelial cells are susceptible to congenitally acquired Zika virus.

New Assay Efficacious for Diagnosing Extrapulmonary Tuberculosis and Rifampin Resistance

New Assay Efficacious for Diagnosing Extrapulmonary Tuberculosis and Rifampin Resistance

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Xpert MTB/RIF may be helpful for confirming a diagnosis of extrapulmonary tuberculosis and can accurately detect resistance to rifampicin.

 ALT-70 Model Provides Accurate Diagnosis of Lower Extremity Cellulitis

ALT-70 Model Provides Accurate Diagnosis of Lower Extremity Cellulitis

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The widespread implementation of ALT-70 into clinical practice may help decrease misdiagnosis rates of lower-extremity cellulitis.

Tuberculosis Assessment More Efficient With Sputum Molecular Testing

Tuberculosis Assessment More Efficient With Sputum Molecular Testing

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In patients with possible tuberculosis, sputum molecular testing may facilitate a more accurate and efficient assessment of disease.

Review of Diagnostic Tools for Necrotizing Soft Tissue Infections

Review of Diagnostic Tools for Necrotizing Soft Tissue Infections

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The journal Annals of Emergency Medicine recently published an article reviewing the tools used to diagnose necrotizing soft tissue infection.

Aptima and RealTime Assay Have High Concordance in Monitoring HIV Viral Load

Aptima and RealTime Assay Have High Concordance in Monitoring HIV Viral Load

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The Aptima assay has 6-sigma performance, high concordance with the RealTime reference assay, and is user friendly and efficient, making it a good choice for laboratories that perform routine monitoring of HIV-1 viral loads.

Suboptimal Diagnostics Affect Management of Tickborne Diseases

Suboptimal Diagnostics Affect Management of Tickborne Diseases

Diagnostic and surveillance limitations and lack of treatment options, vaccines hamper efforts.

Point-of-Care Anti-Toxoplasma Antibody Test Can Reduce Costs and Morbidity

Point-of-Care Anti-Toxoplasma Antibody Test Can Reduce Costs and Morbidity

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The adoption of a point-of-care test to detect Toxoplasma gondii infection would substantially reduce costs and require significantly less infrastructure than conventional testing.

USPSTF Reaffirms Screening Recommendations for Syphilis in Pregnancy

USPSTF Reaffirms Screening Recommendations for Syphilis in Pregnancy

The USPSTF recommends screening all pregnant women for syphilis infection.

Zika Virus and Dengue Fever May Be Distinguished by Select Clinical Indicators

Zika Virus and Dengue Fever May Be Distinguished by Select Clinical Indicators

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Diagnostic indicators including conjunctivitis, platelet count, and monocyte count can be used to reliably distinguish between Zika virus and dengue fever.

Regular Feedback May Optimize Blood Culture Sample Volumes in the PICU

Regular Feedback May Optimize Blood Culture Sample Volumes in the PICU

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Interventions that included the distribution of simple weight-stratified guidelines for recommended blood volume and feedback to physicians were effective in optimizing blood volume culture in a PICU.

Prognostic Biomarkers to Guide Antibiotic Therapy in Critically Ill Patients

Prognostic Biomarkers to Guide Antibiotic Therapy in Critically Ill Patients

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Proadrenomedullin and procalcitonin have demonstrated superiority to C-reactive protein for predicting mortality and guiding antimicrobial therapy in critically ill patients with fever.

Delays in Lactate Testing Associated With Delayed Antibiotics, Increased Mortality in Sepsis

Delays in Lactate Testing Associated With Delayed Antibiotics, Increased Mortality in Sepsis

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Delayed lactate measurement is associated with delayed antibiotic administration and increased mortality in patients with increased lactate levels.

Rapid Diagnostics Reduce Time to Optimal Antimicrobial Therapy in Children

Rapid Diagnostics Reduce Time to Optimal Antimicrobial Therapy in Children

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Time to optimal antimicrobial therapy for positive blood cultures was assessed in a pediatric population.

Platform Manufacturing May Speed Pandemic Vaccine Development

Platform Manufacturing May Speed Pandemic Vaccine Development

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With the advent of platform manufacturing technology, vaccines can be developed quickly to stop the spread of outbreaks.

Procalcitonin Is Effective Biomarker for Guiding Antibiotic Treatment in Sepsis

Procalcitonin Is Effective Biomarker for Guiding Antibiotic Treatment in Sepsis

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Researchers conducted a literature review to assess the effectiveness and safety of procalcitonin to guide treatment in patients with known or suspected sepsis.

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