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MicroRNAs in Infectious Disease: Emerging Clinical Applications

MicroRNAs in Infectious Disease: Emerging Clinical Applications

MicroRNAs are currently under investigation for various clinical applications in infectious disease because of their role in host response to infection and effects on innate and adaptive immune pathways.

Diagnostics

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Delays in Lactate Testing Associated With Delayed Antibiotics, Increased Mortality in Sepsis

Delays in Lactate Testing Associated With Delayed Antibiotics, Increased Mortality in Sepsis

Delayed lactate measurement is associated with delayed antibiotic administration and increased mortality in patients with increased lactate levels.

Rapid Diagnostics Reduce Time to Optimal Antimicrobial Therapy in Children

Rapid Diagnostics Reduce Time to Optimal Antimicrobial Therapy in Children

Time to optimal antimicrobial therapy for positive blood cultures was assessed in a pediatric population.

Platform Manufacturing May Speed Pandemic Vaccine Development

Platform Manufacturing May Speed Pandemic Vaccine Development

With the advent of platform manufacturing technology, vaccines can be developed quickly to stop the spread of outbreaks.

Procalcitonin Is Effective Biomarker for Guiding Antibiotic Treatment in Sepsis

Procalcitonin Is Effective Biomarker for Guiding Antibiotic Treatment in Sepsis

Researchers conducted a literature review to assess the effectiveness and safety of procalcitonin to guide treatment in patients with known or suspected sepsis.

Predictors of Post-Chikungunya Chronic Polyarthralgia

Predictors of Post-Chikungunya Chronic Polyarthralgia

Researchers reported on the first outbreak of an Asian lineage of chikungunya virus in Aruba.

Early Flow Cytometry Predictive of Clinical Deterioration in Sepsis

Early Flow Cytometry Predictive of Clinical Deterioration in Sepsis

Increased circulating immature granulocytes at the acute phase of sepsis are linked to clinical worsening, especially when associated with T-cell lymphopenia.

Simple Blood-Based PCR Test Can Predict Progression to Tuberculosis

Simple Blood-Based PCR Test Can Predict Progression to Tuberculosis

Study identifies and validates a simple PCR-based test from accessible blood samples that predicts TB in heterogeneous African populations with intermediate to high TB burdens.

Pediatric Pneumonia: Sensitivity of Lung Ultrasound vs Chest Radiography

Pediatric Pneumonia: Sensitivity of Lung Ultrasound vs Chest Radiography

Lung ultrasound was more effective in diagnosing pediatric community-acquired pneumonia than chest radiography.

Molecular Laboratory Test Can Discriminate Sepsis From Noninfectious SIRS

Molecular Laboratory Test Can Discriminate Sepsis From Noninfectious SIRS

The SeptiCyteTM LAB may be an effective complementary diagnostic tool to clinical assessment of critically ill adult patients in discriminating between sepsis and noninfectious systemic inflammation syndrome.

New Rabies Test Could Radically Change Testing and Treatment

New Rabies Test Could Radically Change Testing and Treatment

A new rapid rabies test for animals could revolutionize screening and spare humans unnecessary painful treatment.

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