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MicroRNAs in Infectious Disease: Emerging Clinical Applications

MicroRNAs in Infectious Disease: Emerging Clinical Applications

MicroRNAs are currently under investigation for various clinical applications in infectious disease because of their role in host response to infection and effects on innate and adaptive immune pathways.

Diagnostics

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Evidence of Zika Congenital Syndrome in Pre-Term Newborn

Evidence of Zika Congenital Syndrome in Pre-Term Newborn

Case-study demonstrates that epithelial cells are susceptible to congenitally acquired Zika virus.

New Assay Efficacious for Diagnosing Extrapulmonary Tuberculosis and Rifampin Resistance

New Assay Efficacious for Diagnosing Extrapulmonary Tuberculosis and Rifampin Resistance

Xpert MTB/RIF may be helpful for confirming a diagnosis of extrapulmonary tuberculosis and can accurately detect resistance to rifampicin.

ALT-70 Model Provides Accurate Diagnosis of Lower Extremity Cellulitis

ALT-70 Model Provides Accurate Diagnosis of Lower Extremity Cellulitis

The widespread implementation of ALT-70 into clinical practice may help decrease misdiagnosis rates of lower-extremity cellulitis.

Tuberculosis Assessment More Efficient With Sputum Molecular Testing

Tuberculosis Assessment More Efficient With Sputum Molecular Testing

In patients with possible tuberculosis, sputum molecular testing may facilitate a more accurate and efficient assessment of disease.

Review of Diagnostic Tools for Necrotizing Soft Tissue Infections

Review of Diagnostic Tools for Necrotizing Soft Tissue Infections

The journal Annals of Emergency Medicine recently published an article reviewing the tools used to diagnose necrotizing soft tissue infection.

Aptima and RealTime Assay Have High Concordance in Monitoring HIV Viral Load

Aptima and RealTime Assay Have High Concordance in Monitoring HIV Viral Load

The Aptima assay has 6-sigma performance, high concordance with the RealTime reference assay, and is user friendly and efficient, making it a good choice for laboratories that perform routine monitoring of HIV-1 viral loads.

Suboptimal Diagnostics Affect Management of Tickborne Diseases

Suboptimal Diagnostics Affect Management of Tickborne Diseases

Diagnostic and surveillance limitations and lack of treatment options, vaccines hamper efforts.

Point-of-Care Anti-Toxoplasma Antibody Test Can Reduce Costs and Morbidity

Point-of-Care Anti-Toxoplasma Antibody Test Can Reduce Costs and Morbidity

The adoption of a point-of-care test to detect Toxoplasma gondii infection would substantially reduce costs and require significantly less infrastructure than conventional testing.

USPSTF Reaffirms Screening Recommendations for Syphilis in Pregnancy

USPSTF Reaffirms Screening Recommendations for Syphilis in Pregnancy

The USPSTF recommends screening all pregnant women for syphilis infection.

Zika Virus and Dengue Fever May Be Distinguished by Select Clinical Indicators

Zika Virus and Dengue Fever May Be Distinguished by Select Clinical Indicators

Diagnostic indicators including conjunctivitis, platelet count, and monocyte count can be used to reliably distinguish between Zika virus and dengue fever.

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