Prompt diagnosis of tick-borne diseases is essential but testing methods have been imprecise. Learn about some recent testing advances for Lyme disease and other tick-borne illnesses.
Researchers validated the clinical sensitivity of the T2Candida panel for the diagnosis of bloodstream infections caused by the 5 most common pathogenic Candida species.
Babesia parasites are transmitted by common deer ticks, with approximately 1000 to 2000 cases reported each year primarily in Northeastern and Midwestern states.
A novel method - Antibody Detection by Agglutination-PCR (ADAP) - was developed to diagnose HIV in oral fluid samples. ADAP is both highly sensitive and highly specific and may allow noninvasive early diagnosis of HIV in population-based screening efforts.
Adults aged 65 and older hospitalized with fever or respiratory symptoms during influenza season are less likely to undergo a provider-ordered influenza test than younger adults.
Investigators assessed the need for conducting routine voiding cystourethrograms in infants diagnosed with urinary tract infection.
The utilization of this tool could prevent severe complications secondary to delayed pneumonia diagnosis and treatment.
MRSA nares screening can be a stewardship tool to streamline empiric antibiotic therapy among those not nares colonized with MRSA.
No moderate- or high-level evidence was found that SEP-1 or its hemodynamic interventions increase survival in septic adults.
Polyomavirus JC-DNA assessment in plasma samples might complement progressive multifocal leukoencephalopathy diagnosis, especially when cerebrospinal fluid (CSF) is unavailable or polyomavirus JC-DNA is not detectable in CSF.
A study found that nontargeted screening using antigen-antibody tests identified previously undiagnosed HIV infection at a rate that exceeded the CDC screening threshold by severalfold.
Airborne influenza viruses may be safely and effectively eradicated with continuous low doses of far ultraviolet C light.
Systemic inflammatory response syndrome criteria may be more sensitive than quick sequential organ failure assessment for predicting mortality in patients with suspected infectionFebruary 07, 2018
The systemic inflammatory response syndrome (SIRS) criteria were poorly specific but more sensitive than quick Sequential Organ Failure Assessment (qSOFA), which supports the use of the SIRS criteria as a screening tool for patients with infection who are in danger of further decline.
A simple diagnostic test aids in the early and accurate detection of respiratory viral infection.
For febrile infants age 60 days and younger, urinalysis is highly sensitive and specific for diagnosing UTIs.
The Food and Drug Administration has granted clearance for UriVarx urinary tract infection test strips for use in patients with overactive bladder and urinary incontinence.
Urinalysis had ≥90% sensitivity and specificity in identifying urinary tract infection (UTI) among infants ≤60 days old with fever, regardless of presence of associated bacteremia. Sensitivity of urinalysis was slightly higher among infants with associated bacteremia compared to those without, however specificity remained constant.
Following vascular reconstruction, patients will receive postdischarge care that includes telehealth electronic monitoring.
Confirmatory testing is valuable and cost-effective for assessing HIV in infants considering false-positive rates of more than 10% when using nucleic acid amplification testing.
Chest X-rays do not differentiate between viral and bacterial pathogens, and they do not subsequently alter the course of treatment.
The FDA announced a new website that provides direct access to information about appropriate antibiotic choices.
A study evaluated whether influenza testing can be performed more comfortably by taking midturbinate swabs without compromising test sensitivity.
MicroRNAs are currently under investigation for various clinical applications in infectious disease because of their role in host response to infection and effects on innate and adaptive immune pathways.
A test-and-not-treat strategy may help areas in which loiasis is endemic and onchocerciasis is hypoendemic so that individuals who are not at risk for serious adverse events are safely given ivermectin treatment.
Successive negative HPV and cytology co-testing is linked decrease risks of cervical cancer.
A representative from the California Department of Public Health discusses latent TB infection testing and treatment recommendations and reasons why US physicians have been slow to test for and treat for the condition.
Although detection of Zika virus from conjunctiva has been previously reported, presence of Zika virus RNA in conjunctiva at the late convalescent phase of the disease was not known.
In critical care setting, thrombophlebitis can develop as a consequence of invasive procedures and, in case of bacteremia, it might represent a suitable medium that sustains bacterial growth and subsequent persistent endovascular infection.
Results from this study are novel with respect to the combined use of leukocyte count, procalcitonin, interleukin-6, and paraoxonase-1 activity for mortality prediction.
Diagnosing Lyme disease can be difficult because symptoms vary from one person to another and can resemble symptoms of other infectious diseases spread by ticks.
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Infectious Disease Advisor Articles
- Major Advances on Horizon for Tick-Borne Disease Testing
- Measles Vaccination After Third Dose of DTP Vaccine May Improve Child Survival
- Vegetation Size May Increase Mortality Risk in Infective Endocarditis
- FDA Approves Blood Screens for Tickborne Parasite
- Effect of Vaccine Antigen Exposure in First 23 Months of Life
- Substantial Variation in HIV Diagnoses Among Persons Aged 13 to 29 Years
- Obesity, Older Age, and Pretreatment Cirrhosis Delay Fibrosis Improvements in HCV
- Oseltamivir Does Not Increase Suicide Risk in Pediatric Population
- Hepatitis C Eradication With DAAs Improves Carotid Atherosclerosis
- CDC Reports Number of Noncongenital Zika Virus Cases in the United States