Hereditary angioedema:

Indications for FIRAZYR:

For acute attacks of hereditary angioedema (HAE).

Adult Dosage:

≥18yrs: 30mg SC in abdominal area; may give additional doses at intervals of at least 6hrs if response inadequate or symptoms recur. Max 3 doses/24hrs.

Children Dosage:

<18yrs: not established.

FIRAZYR Warnings/Precautions:

Advise patients to seek medical attention after treating laryngeal attack given the potential for airway obstruction. Elderly. Labor & delivery. Pregnancy. Nursing mothers.

FIRAZYR Classification:

Bradykinin B2 receptor antagonist.

FIRAZYR Interactions:

May attenuate the antihypertensive effect of ACE inhibitors.

Adverse Reactions:

Inj site reactions, pyrexia, transaminase increase, dizziness, rash.

Drug Elimination:

Renal.

Generic Drug Availability:

NO

How Supplied:

Single-use prefilled syringe (3mL)—1, 3