Indications for INFED:

Iron deficiency where oral therapy is unsatisfactory or impossible.

Adults and Children:

<4mos: not recommended. Give by IV or deep IM inj into upper outer quadrant of buttock only. Administer 0.5mL test dose first; if no signs/symptoms of anaphylactic-type reactions, may give full therapeutic dose. ≥4mos: Iron deficiency anemia: determine total dose based on hemoglobin and body weight (see full labeling). Iron replacement for blood loss: Replacement iron (in mg) = blood loss (in mL) × hematocrit. Max daily doses: <5kg: 0.5mL (25mg), <10kg: 1mL (50mg), ≥10kg: 2mL (100mg).

INFED Contraindications:

Anemias not associated with iron deficiency.

Boxed Warning:

Risk for anaphylactic-type reactions.

INFED Warnings/Precautions:

Monitor for signs/symptoms of anaphylactic-type reactions, esp. in patients with history of drug allergies, asthma; have epinephrine available. Avoid large IV doses: higher incidence of adverse events. Severe hepatic impairment. Avoid during acute phase of infectious kidney disease. Dialysis. Cardiovascular disease. May reactivate quiescent rheumatoid arthritis. Neonates. Pregnancy. Nursing mothers.

INFED Classification:


INFED Interactions:

Concomitant ACE inhibitors may increase the risk for anaphylactic-type reactions. May falsely elevate serum bilirubin or decrease serum calcium levels.

Adverse Reactions:

See full labeling. Anaphylactic reactions (may be fatal; even if test dose was tolerated), cardiovascular events, pruritus, GI upset, arthralgia, arthritis, inj site reactions, others; possible IM inj site tumors, sepsis in neonates.

Generic Drug Availability:


How Supplied:

Vials (2mL)—10

Pricing for INFED

2ml of 50mg/ml vial (Qty: 1)
Appx. price $36