Topical pain relief:

Indications for: SYNERA

For local dermal analgesia for superficial venous access and superficial dermatological procedures (eg, excision, electrodessication, shave biopsy of skin lesions).

Adults and Children:

<3yrs: see full labeling. Apply to intact skin. ≥3yrs: Prior to venipuncture or IV cannulation: apply for 20–30mins. Superficial dermatological procedures (eg, excision, shave biopsy): apply for 30mins prior to procedure. Remove patch if irritation or burning sensation occurs. Do not cut patches or remove top cover (may cause thermal injury). Do not cover holes on top side of patch.

SYNERA Warnings/Precautions:

Risk of methemoglobinemia (esp. in G6PD deficiency, congenital or idiopathic methemoglobinemia, cardiac or pulmonary compromise, infants <6 months of age, concurrent exposure to oxidizing agents or metabolites); monitor. Avoid simultaneous or sequential application or for longer than recommended. Remove before undergoing MRI (contains iron powder). Avoid eyes, mucous membranes, broken or inflamed skin, inadvertent trauma (eg, scratching, rubbing, exposure to extreme temperatures). Effect on intradermal live vaccines undetermined. Severe hepatic disease or pseudocholinesterase deficiency. Acutely ill or debilitated. Elderly. Pregnancy. Nursing mothers: avoid direct infant exposure.

SYNERA Classification:

Topical anesthetic.

SYNERA Interactions:

Increased risk of methemoglobinemia when concurrently exposed to nitrates/nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, others. Toxicity may be potentiated by Class I antiarrhythmics (eg, tocainide, mexiletine). Additive effects with other products containing local anesthetics.

Adverse Reactions:

Local reactions (eg, erythema, blanching, edema), anaphylactoid reactions.

Generic Drug Availability:

NO

How Supplied:

Patches—1, 10

Pricing for SYNERA

70mg/70mg patch (Qty: 10)
Appx. price $182
GoodRx